The frequency of hypertension and obesity in a sample of the rural indigenous population (457 people aged 20 years and older) of the Republic Sakha (Yakutia) was studied. It was found that 40% of the surveyed population had arterial hypertension. Obesity was revealed in 14% of males and 19% of females, abdominal obesity in 42 and 55%, respectively. Blood pressure level positively correlates with body mass index and the waist circumference. Information content of these indicators at identifying individuals with high risk of hypertension did not differ. The prevalence of abdominal type of obesity requires the study of its contribution to morbidity and mortality from chronic non-communicable diseases, constitutional features of a given population and the subsequent possible development of specific ethnic criteria for obesity.

The article provides the authors’ data on the correlation of HLA аntigens with lipid indices in psoriasis patients in the Khabarovsk Krai. The study of psoriasis patients revealed the increased incidence of HLA- A 1 (p <0,001), -B13 (p <0,001), -B 17 (p < 0.001) and negative HLA-A28 (p < 0.001), -B7 ( p <0,01), -Cw 3 (p <0,01), -Cw 4 (p < 0.01).

The study shows the connection of total lipids, triglycerides and total cholesterol indices with the increased frequency of HLA-A 1 (p <0,001), -B13 (p <0,001), -B17 (p < 0.001) in psoriasis patients.

The authors have developed an alternative method of extrapleural surgical collapse thoracoplasty for the treatment of destructive forms of pulmonary tuberculosis. The proposed operational technique meets all requirements of surgical collapse operations in the treatment of respiratory tuberculosis, at the same time has a high cosmetic efficacy and significantly less traumatic in contrast to previously developed traditional ways of thoracoplasty at pulmonary tuberculosis.

We used populational one-shot study materials obtained within the project <HAPIEE> in 2002-2005 (“Determinants of cardiovascular diseases in Eastern Europe: a cohort study”). In 73.2% (6875) of sample (9397 prs) aged 45-69 years we studied respiratory function: triple measurement of forced expiratory volume in 1 second (FEV1), forced vital capacity (FVC). In studying the possibility of bronchial obstruction syndrome (BOS) for individuals with a history of smoking in relation to non-smokers it was found that in male smokers BOS formed in 3.2 times more often, in women - smokers – in 1.7 times more often than in non-smokers; in men - ex-smokers BOS formed in two times more often, in female ex-smokers – in 2.1 times more often than in non-smokers; in periodically smoking persons there was no tendency to BOS. At the analysis of population indices we revealed negative correlation of BOS components (FEV1, FEV1/FVC) with smoker index. The results showed that smoking history, intensity and duration of smoking affect the BOS formation.

In order to verify the lunasensor theory of brain aging presumptive functionally related morphological markers sensitive to the changes of the moon phases were selected in the model experiment on rats using methods of quantitative light microscopy. Histological evidences of the ability of morphological markers to change some of its properties in various phases of the moon were obtained.

The influence of frequency of an ischemic (coronary) heart disease (ICD) was analyzed. The frequency of heart ischemic attacks and insults had been compared with a level of geomagnetic activity in Yakutsk - the Far North in Russia. Founded data confirmed influence of geomagnetic indignation and geomagnetic storms: In the periods without geomagnetic indignation (186,3 days) in year (Yakutsk), number of heart ischemic attacks (2.9 times) and brain insults (3,29 time) are less than in the days of geomagnetic storms. This data has interest for the experts of the Far North, who plan of prevent actions against to heart and brain ischemic mortality.

In order to evaluate the effectiveness of forecasting algorithms of infectious-toxic shock and DIC at pneumonia, we did a comparative analysis of the two groups of patients. It was revealed that the proposed diagnostic algorithms for the prediction of the infectious-toxic shock and DIC help the practitioners, including at the stage of primary health care in the early stages of development to suspect the possibility in a patient with pneumonia potentially fatal complications, which allows to adjust medical and diagnostic tactics, more accurately resolve transportation of the patient, to determine the indications for hospitalization, including to the emergency department and intensive care.

This work reviews aspects of the research tools and the quality of life of children with chronic gastroduodenal pathology.

The article presents the clinical observations of short episodes of losses of consciousness among the Civil aviation specialists, which make a threat to the flights safety. From 2000 to 2011 192 episodes were recorded. In 29.17 % of cases epileptic seizures were diagnosed, in 70.83 % - transient disorders of consciousness of non-epileptic origin. Results of a comprehensive survey showed features of clinical manifestations among the various categories of aviation professionals. At the deciding a question on the professional serviceableness at the medical-flight examination an individual and a balanced approach is necessary that takes into account gender, age, etiology, previous medical examination, etc.

The questions of adequate medical training, using new forms of organization and technology training, establishment of modern management services that ensure the efficient management of staff performance were discussed.

In order to improve the quality of care for neonates with surgical diseases we examined the primary causes of newborn deaths in the period from 1992 to 2011 according to the children’s surgical department of Yakutsk data. In 77% of cases the causes of adverse outcomes in neonates with surgical pathology were conditionally preventable. We identified the main organizational direction, which led to a reduction in mortality of infants with surgical pathology in 3, 5 times during the 2 study period. Basic medical and organizational moments of regional model improving medical care for newborns with surgical pathology are antenatal diagnosis of malformations and prenatal consultation by pediatric surgery, competent and timely transportation of the newborns from regions, centralization assist in the level 3 hospital, introduction of modern diagnostic and treatment algorithms, methods of minimally invasive surgery.

The study is based on results of energy value and macronutrient composition of breast milk research and its relationship to diet of lactating women of different ethnic groups living in the Republic Sakha (Yakutia). We revealed that the energy value and the macronutrient composition of breast milk to a large extent were determined by ethnicity and region of residence of women.

The analysis of the main indicators of the primary disability of the adult population in the Republic Sakha (Yakutia) in the period from 2009 to 2012 was done. The primary disability of the working population in the same period, including a comparative perspective by districts (uluses) was separately analyzed.

The article reviews the literature on the problem of hemodynamic and water balance in pregnant women with preeclampsia, anesthetic management of this category of patients. Understanding the degree of dysfunction of organs and systems in pregnancy associated with preeclampsia is extremely important for anesthesiologist, because it affects the tactics of the patient, the choice of anesthesia and therapy program.

The article reviews the literature on the history and development of medicine and health in the Far East of Russia. It is noted that the available scientific research and publication does not provide a complete picture of healthcare development in the Russian Far East, because they not cover all territorial, historical, chronological and socio- economic framework of this process. Moreover, the development of medical specializations, including dental services, covered not enough, perfunctorily within the whole health care system. There is required a deep analysis of the early development of dental care, taking into account the geographical, social and political conditions that would avoid the mistakes of the past, to find the optimal path of development and to provide quality and affordable dental care at various social levels.

This review presents and summarizes the results of recent studies on dehydroepiandrosterone (DHEA) which plays an important role in longevity regulation. During ontogenesis DHEA and DHEA-sulfate content steadily declines. At the same time, the mechanisms regulating secretion of these hormones and factors determining their age dynamics remain largely unsolved. The paper presents different mechanisms of regulation of adrenal secretion of DHEA and DHEA-sulfate involving adrenocorticotropic hormone (ACTH), prolactin, luteinizing hormone and insulin.

The literary review points out the fact that different races (European, Afro-Americans, Mongoloids) are subject to one or another form of glaucoma owing to the certain anatomic features of eyes. The carried-out literary review revealed variability of incidence and prevalence of the primary glaucoma (PG) not only among various races, but also in each of them, and also showed the relevance of epidemiological surveys in various ethnic groups.

Within the program of pediatrics service modernization in the Republic Sakha (Yakutia) in 10 arctic districts: Anabarsky, Abyjsky, Oleneksky, Bulunsky, Ust-Yansky, Allaikhovsky, Nizhne-Kolymsky, Sredne-Kolymsky, Zhigansky and Kobyasky fixed automated systems of prophylactic examination are set. In this article the results of using given technologies are presented. The article presents some results of using this technology.

The authors made a comparative analysis of the clinical characteristics of the two groups of Vilyuisky encephalomyelitis (VE) patients to assess the role of inflammatory responses in the development of neurodegenerative processes in this disease. In our paper we show that at inflammatory onset of the disease younger age debut of disease and more expressed clinical symptoms are observed.

Inflammatory reactions make complications and exacerbate the severity of the clinical course of the disease, accelerating neurodegeneration in patients with primary encephalopathy (a special form of encephalopathy, which leads to the VE development).

The authors proved high informative content of the computed tomography (CT), on the basis of the study of diagnostic informative content of radiographic research methods used in the survey of children and adolescents on primary pulmonary tuberculosis. CT diagnostic significance indicators exceed informative content of traditional radiographic techniques (radiography and linear tomography) in 2-2.5 times. A comparative assessment of radiation doses received during conventional radiological methods and CT is given. The authors revealed the dependence of the received radiation dose from the age, the highest radiation burden falls on young children and adolescents. In the result of the research, a high radiation dose at linear tomography at low diagnostic informative content was defined, thus indicating the need to abandon this method at testing children and adolescents to primary tuberculosis, in favor of CT.

In the present article we presented the study results of the dynamics of injury indicators of different etiology among children of the Sakha Republic (Yakutia). We marked increase in the number of home, school and beating injuries among children. At analyzing the age characteristics of injuries we revealed the greatest number of home injuries among children in the age period from 2 years to 5 years, street injuries in children from 7 to 13 years. We also marked seasonality of the street and car injury with the increase in spring and summer (March-May - June-August). Seasonality of bite injuries in the summer (June -July-August) was noted

The case of ultrasonic diagnostics of congenital heart disease – a syndrome of the lack of a pulmonary artery valve I option in term of pregnancy 23 weeks is presented. By ultrasonic research of heart and the main vessels a substantial pulmonary trunk and arteries distension is revealed, pulmonary valves are visualized in the form of rudimentary structures, high ventricular septal defect, and dextraposition of aorta were found. Other developmental anomalies weren’t revealed. After prenatal consultation in the conditions of medical genetic consultations the family made the decision on pregnancy interruption. By pathoanatomical research the prenatal ultrasonic diagnosis was confirmed.

Production of the northern domestic and trade animals, nature gifts has a high nutritional value because it contains large amounts of proteins, fats, minerals, vitamins and biologically active agents (BAA). Therefore it is a valuable national resource, on the rational use of which it should be paid special attention.