The review of the literature is based on the critical analysis of 30 sources, taking up questions of pathology of the Far North indigenous population. The role of a natural inhabitancy, a traditional way of life and a feeding character on formation of health parameters of the Arctic populations is shown.

The aim was to determine the concentration of anti-inflammatory cytokines (IL-1Ra, IL-4 and IL-10) in the serum of patients with parainfluenza. We examined 19 patients with moderate parainfluenza aged 15-54 years who have the disease run a positive, without complications. Blood were taken during the acute period of disease and reconvalescent. Served as control blood of healthy donors (n = 18). Defined increase in all investigated cytokines in the acute period of disease and during convalescence. We set the activation level of anti-inflammatory “cytokine network” throughout the disease, indirectly indicating the high activity of effector cells of blood, synthesizing data cytokines. The results were used to create an expert system “Quick diagnosis and prognosis of ARVI”.

The authors analyzed the effectiveness of therapy four schemes of basic therapy in 97 children with localized scleroderma. As a result, developed a different approach to the appointment of the basic therapy, taking into account the clinical current of disease.

In work are presented given complex diagnostics of the forms, gravity, complications, chosenned factors of the risk bronchopulmonary dysplasia.

The atopic dermatitis in modern conditions is a serious medical and social problem that is caused by its prevalence, a chronic relapsing current, possibility of formation of early physical inability, is in most cases accompanied by psychosomatic disturbances and characterized by depression of quality of life.

We analyzed the indices of vegetative nerve system with complex technical program ORTO Valeo in male adolescents (Russians and Tyvins), the inhabitants of Saryg-Sep village of Tyva Republic. We revealed varieties in vegetative regulation in adolescents of different ethnic groups at rest and in orthostasis. In Russian boys both at rest and in orthostasis sympathetic influences of VNS prevailed. Baseline vegetative tonus was characterized by domination of regulation of sympathetic type. In the Tyvins the most frequent type of baseline vegetative tonus was vagotony. Eutonia was frequent as well, which proves high efficiency of vegetative regulation processes in them.

The aim of the study was to examine the frequency and structure of arrhythmias and heart conduction disorders in patients with uncontrolled asthma. Was analyzed 245 records of patients with bronchial asthma, among whom 28 (11.4%) patients with mild, 122 (49,8%) - moderate, and - 95 (38,8%) severe.
The analysis suggests that more than half of patients with asthma, there is an abnormal heart rhythm, among which the predominant change in automaticity of sinus node (sinus tachycardia). With increasing severity BA, there has been an increase in frequency and structure of the conduction disturbances.

The authors have studied clinical and morphological signs of some forms of Lichen rubber planus (LRP) of the mucous lining in the oral cavity that have significant diagnostic value. They have also conducted a comparative analysis of the morphological picture depending on clinical course of the disease.

The work purpose was studying of indicators of a hemostasis in population of Russian and the Buryat at pregnant women with arterial hypertensions.
Hemostasis indicators on sets of reagents firms “Technologies-standards” (Russia) on programmed optic-mechanical коагулометре «Minilab701» at 271 pregnant women without hypertensions of the Buryat and Russian population and 269 pregnant women with an arterial hypertensions of the given populations were analyzed. At pregnant women of Russian population with arterial hypertensions adaptive mechanisms which promote maintenance of indicators прокоагулянтов practically at one level that it is not observed in the Buryat population are noted. The most indicative concerning an arterial hypertensions in the Buryat population in the first and second trimesters of pregnancy is протромбиновое time, in the end of pregnancy of change aggregations with universal индуктором concern soluble complexes мономеров fibrin, to time of curling and duration of a bleeding.

It was analysed case histories of 1205 servicemen at the age of 16 to 57 with community-acquired pneumonia being treated in the pulmonological department of the Branch № 1 of the Federal State Establishment (FSE) “321 District Military Clinical Hospital (DMCH)” of the Ministry of Defense (MD) of the Russian Federation in Novosibirsk in 2003-2005. Productive cough, painful and asthenic syndromes predominated in the clinical picture of servicemen with community-acquired pneumonia; normal and low grade fever of the body were registered more often. In the majority of the examined patients changes in the percussion sound weren’t revealed, on auscultation with the same frequency it was auscultated vesicular, weakened and hard respiration; particularly in the half of cases râles were absent, in their presence there were moist râles and crepitation.

In the present work experimental data about influence of natural zeolite on parameters of defensive behavior in the modular device with use in experiment of white laboratory rats are presented. The obtained data testifies that among the experimental individuals who are in conditions of tool stress, 76% prefer a choice to food in which the mineral additive in the form of the crushed zeolite contains, and indicators of behavioural activity are optimized at the given category of animals.

Results of checkups and treatment of 71 patients with esophageal cancer were analysed. Clinical symptoms of illness, results of instrumental methods of research, immediate and long-term results of surgical treatment, and data about complications of immediate post-operational period, immediate and long-term results of operative therapy are provided.

The presented work is based on the analysis results of complex conservative and surgical treatment 50 patients with the infected forms of pancreatic necrosis, were on treatment in surgical branches of Republican hospital №2 - Center of emergency Republic of Sakha (Yakutia) during the period with 2008 for 2011.
During research it was possible to adapt and improve the scheme of antibacterial therapy applied in treatment pancreatogenic infections in a versatile surgical hospital.
Monitoring carrying out antibacterialresistens and efficiency of antibacterial therapy substantially raises probability of a favorable outcome in treatment of patients with pancreatogenic an infection.

Presents the results of the morphological changes in the cornea by intrastromal implantation of amnion in an experimental model of endothelial epithelial corneal dystrophy in the rabbit.

This article defines urgency of the problem of brittle bones. It describes approaches of surgical correction of this pathology in children, offers original method of surgical treatment of clinical aspects of brittle bones using titanium nickelide materials. The advantage of materials consists in bioinertness and high resistibility. Use of titanium nikelide implants in brittle bones treatment process reduces recovery period and improves quality of life of patients.

At this article the analysis of deaths causes in the Republic of Sakha (Yakutia) is presented. Revealed the leading role of external factors as causes of death. Analyzed by age, gender and social differences.

One of the main causes of maternal mortality are obstetric hemorrhage. A feature of obstetric hemorrhage is sudden and their massiveness. In recent years, new technologies are introduced to conserve blood in clinical practice. This paper describes the first clinical experience, during which the method of reinfusion of autoerythrocytes by using apparatus Cell Saver 5 is used for Caesarean section for a patient with an extremely high risk of bleeding in a Perinatal Center of the RH №1-National Medical Center of MH of RS(Y).

The authors studied possibilities of application of immunohistochemical method in diagnostics of peripheral lymph nodes tuberculosis. it was found out that the method allowed to increase frequency of mycobacterium tuberculosis revealing in comparison with the other methods in 2 times.

Questions of introduction of a new form of the organization of the ophthalmological aid which will allow to satisfy requirements for cataract surgery are considered, to liquidate the turns on planned operative treatment for patients with a cataract in the Republic Sakha (Yakutia).

The paper describes accounting data and experiences of a pediatric intensive consulting care brigade of the Territorial centre of medicine disasters Republics Sakha (Yakutia) by the Russian Federation in 2007-2009 yare are analyzed. The structure of diseases is studied; the estimation of the specialized help on places and during transportation is spent. It is revealed, that 25,6 % of departures are made at respiratory insufficiency, at an infectious-inflammatory syndrome-22,2%, at a syndrome of sharp cerebral insufficiency-20,2%. The overwhelming majority of children with a surgical pathology (about 85 %) are victims with a burn trauma. Brigade work in region demands perfection and modernization.

Presentation of an analysis of expert evaluation of medical care provided to patients of the rheumatological department in healthcare organizations in Yakutsk city. The results of expert evaluation found groups of medical errors, which have conditional value of the risk index of medical errors in the delivery of outpatient care.

Research of system of medical maintenance of pupils child – youthful sports schools of a city of Yakutsk according to the Republican center of physiotherapy exercises and sports medicine is conducted. Problems of organizational character in medical maintenance of young sportsmen are revealed: a severe shortage of medical shots and insufficient it is material – technical base, both in the republican center, and at child-youthful schools; absence of the medical block at sports schools; absence of continuity between the center of physiotherapy exercises both sports medicine and an out-patient-polyclinic link.
The offered system of perfection of medical maintenance of pupils child – youthful sports schools, including system of selection of children for employment by various sports at municipal level will allow to improve quality of rendering of medical aid and to lower level of disease of young sportsmen without additional financial expenses.

Social-economic position to families is an important factor, including upon mothers’ pregnancy current and level of newborns’ health. Middle term of stating on account at Khabarovsk territory is about 19,31± 0,56 weeks. Middle level of evaluation on Apgar scale is 7,68±0,24 between newborns of the observed women. The positive communication between the period of stating on account and evaluation on the Apgar scale (r=0,76±0,11) has been proved as well as the positive connection between the physiological pregnancy and frequency of breastfeeding (r=0,87±0,11).

Here, we report results of long-term complex epidemiological and microbiological monitoring of yersinioses in Yakutia. The circulating pathogenic yersinia strains were screened for presence of the major virulence genes. A persistence of human- and rodent- non-pathogenic Y. enterocolitica biotype 1А and Y. kristensenii in the internal organs of the most prevalent rodent species was detected.

The epidemiological situation of tuberculosis, combined with HIV-infection in the Irkutsk region is unfavorable because of the regions with the largest incidence of both infections. The study of medical and social characteristics of revealed that TB patients combined with HIV infection are in most cases, the were not social and adopted persons (75.5%). According to the appealability (74.8%) combined pathology is revealed in health care establishments. TB develops on HIV-infection background (91.6%) and is characterized by an increase in the proportion of heavy and acutely progressive forms (37.3%).

Conditions of placing and feature of a food of the military men serving in territory of the Irkutsk region are studied. Essential infringements of sanitary-and-hygienic norms of household arrangement of military men are revealed. Low caloric content and imbalance of a food allowance is established. Results of research testify to necessity of correction of system of safety of military service for health of young men.

This article present information about children was treated in Pediatric center of National medical center of the Republic of Sakha Yakutia with 2001 to 2010 and analysis of the levels of morbidity. This results of analysis is present that for this periods is raised morbidity rate of the some diseases group, in republic provide organization work for medical examination children. Detected that for this period is raised ecology-association diseases.

The research analyzes road accidents (RA) in the Sakha Republic (Yakutia) for the period 2001-2010. This includes major causes of accidents on the republic’s roads, their frequency split for different regions, as well as road accident mortality. It has been revealed that the road accident mortality on M-56 federal motorway is 2-2.5 times higher than in population aggregates.

Illegitimate births in the Republic of Sakha (Yakutia) increased by 6.4% for the last decade. The increase of the fertility out of wedlock in a group of young mothers (under 20) is an important social problem.
It was found that pregnancy was complicated for 72.3% mothers of unregistered marriage. Among the diseases of children born outside marriage, there were birth defects, intrauterine growth retardation, morphofunctional immaturity, prolonged jaundice. Perinatal CNS involvement is twice higher than that of children born in wedlock. Every fourth illegitimate child is born prematurely.
However till now, despite scientifically-practical importance of a problem, obvious deficiency of works, devoted to this group of the raised medicine-social risk.

The article represents an overview of the literature on fetal alcohol syndrome. Also here is presented diagnostics criteria, recognition of facial features, perspective of treatment.

On this article present a date of the health cares system modernization in Republic of Sakha Yakutia. Present the optimal scheme of the dynamic examination children living on the rural territory using automatic technology and organization medical expedition.

As a result of pharmacoeconomic analysis found that the greatest costs associated with the treatment of severe manifestations of allergic reactions to drugs. In the treatment of allergic reactions of moderate forms of economically viable single intramuscular injection of «Suprastin», then in children under one year application of the «Fenkarol», in children over the year – «Parlazin».

In most cases, atrial septal defect closure of the heart can be treated in childhood before the age of five. In practice there are some cases when patients can be diagnosed with this illness in adulthood. Such patients could not have consultations with doctors using large diagnostic capabilities of modern equipment of the clinic. Such case is described in this article.

To analyze cervical esophagogastroanastomosis strictures development pattern and critical periods after gastric tube esophagoplasty for benign esophageal diseases, to estimate endoscopic interventions efficacy at anastomosis. Patients after esophagogastroplasty need early follow-ups for timely anastomotic stricture detection and correction.

In the department of the Yakutsk Republican Ophthalmologic Clinic (YROC) the intraocular lenses Acrysof IQ Restor +3,0 have been implanted to patients with complicated cataract .
Our experience of implantation of diffractional and refractional lenses Acrysof IQ Restor +3,0 testifies that given IOL model allow to achieve pure sight as afar as closely, and in the average distance as well.