The purpose of research. The analysis of prevalence and clinical features of the 2-type diabetes mellitus (DM2) in Yakutia.
Material and methods. The database “ The State register of diabetes in RS (Y)”, the demographic data of population census. Results. Steady distribution of diabetes due to DM2 is revealed, and besides among agricultural uluses in places of traditionally prevailing residing of the Yakut population their greater rate of growth is observed. Relative decrease in frequency of later complications and the expressed sexual disproportion of patients are also marked. The basic later complications negatively influencing on the quality of life are cardiovascular frustrations (heart attacks and insults) and nephropathy (Chronic renal insufficiency).
The conclusion. The regional register of diabetes is the effective tool of monitoring of the population morbidity and an estimation of quality of the treatment-and-prophylactic help of patients of endocrinologic profile, allowing to carry out the control over an epidemiological situation and to provide acceptance of administrative decisions in sphere of public health services.

The purpose of research. To study features of distribution of multifocal malignant tumors and to reveal groups of patients with the raised risk of development of the second malignant tumor in conditions of the Far North.
Material and methods. The retrospective analysis of case records, outpatient cards of 194 patients with tumors for the period 2001-2005 is lead.
Results of research. In RS (Y) the standardized parameter of malignant neoplasms morbidity of population for 2005 has made at men 270,8 0/0000, that is higher on 5,6 % of a level for 1995 (256,50/0000), and at women on 3,6 % (accordingly 176,2 and 170,10/0000). In the beginning of the analyzed period (2001) the parameter of multifocal malignant tumors morbidity on 100 000 of population corresponded 3,30/0000. For five years term the specified parameters exceeded initial levels in 1,7 times (6,00/0000). From them 36,8 % of tumor cases have been defined as synchronous.
The conclusion. Growth of multifocal malignant tumors morbidity in RS (Y) is caused by wide introduction in a clinical practice of highly effective medical products. The increase in life expectancy of patients causes probability of occurrence in them of new (metachronic) tumors. At men enhanced attention demand the persons cured in occasion of malignant tumors of skin, lung, stomach and kidney, at women - a mammary gland, skin, colon and genitals.

Aim. This analysis represents a study of the course of arterial hypertension in the Chernobyl nuclear power station’s liquidators during recent twenty years after accident.
Material and methods. 536 liquidators of the Chernobyl nuclear disaster and 480 patients without radiation’s anamnesis were examined. Differences in course of arterial hypertension between two groups were compared. Appraisal of the results of cliniconeurologic, laboratory and instrumental methods of study were done 10, 15, 20 years later after the accident.
Results. This study demonstrates that liquidators of the Chernobyl nuclear disaster belong to the high-risk group of the early development of arterial hypertension. The clinical course of arterial hypertension is complicated with discirculatory encephalopathy, ischemic disease, and pulse disturbance. Feebly marked stage of arterial hypertension is associated with more serious form of discirculatory encephalopathy.

The purpose of research. Studying within 3 years of diagnostic categories of a myocardial infarction (MI), prodromal period of the diseased.
Material and methods. Research was spent under WHO programs «The Register of an acute myocardial infarction» in Yakutsk among the population at the age of 25-64 years. Since 01.01.2004 till 31.12.2006 in Yakutsk 799 cases of MI are registered.
Results. The diagnostic category “possible MI” is met much more often than “defined MI”. In both diagnostic categories in overwhelming majority of cases the typical clinical picture of disease was observed. But at the same time in a category “defined” myocardial infarction in a significant amount of cases there are also atypical forms of disease. Most often MI develops in house conditions, at the same time MI occurrence was more often on work, in the street - at men or in house conditions - at women. More than at half patients with MI had an arterial hypertension (АH) by strict criteria, in half of cases – angina pectoris (AP), and at every third - old MI. 60, 7 % of male patients are smokers in the present or the past. Distinctions in the characteristic of a painful syndrome during the 2-week period preceding an attack, between groups of the survived and died, are not noted. At the same time more often were met: At died – sudden arrhythmias, a short wind and exacerbation of AP; at the survived - exacerbation of AP and for the first time occurred angina.
The conclusion. Monitoring has shown that within 3 years the MI clinic has not changed and basically is manifested by a typical clinical picture. The fact of presence of considerable number of the diseased having in anamnesis АH, AP, old MI and also intensive smokers that speaks about weakness of preventive work among the population, alerts much.

Within the framework of the Republican program of monitoring of congenital developmental anomalies the analysis of congenital heart diseases at newborns and children under a year from 2003 till 2007 is lead. It is established that mean indices of congenital heart diseases at children under a year with inclusion in number of CHA OOW exceed the Russian parameters.
The basic contribution to quantity of CHA is caused by defects of septa. A plenty of pregnant women have extra genital diseases which can be reason of fetus CHA. The comparative analysis has shown, that at present ecological factors, most probably, do not render influence on frequency of CHA, probably, the genetic and social reasons have crucial importance.

Authors research of 22 patients, 12 patients with visceroptosis, confirmed by X-rey examination and 10 person without a pathology of thick intestines are characteristic is surveyed. Thus, the data Doppler ultrasonic researches at patients with visceroptosis, have revealed decrease in speed of a blood-groove in a belly aorta and top mesenteric arteries in standing position on 16,6 sm/sec. and 20,1 sm/sec accordingly, it is more than. than in control group. These data specify that patients with visceroptosis test chronic abdominal ischemia connected to infringement of a blood-groove in mesenteric vessels, owing to deviation small guts with formation of sites pathological angulations of arteries.

This work is based on results of ultrasonic research of 213 patients with an acute cholecystitis in conditions of the central regional hospital. The base of research is new method of ultrasonic diagnostics with using dopplerography. In result improved forecast in choosing operating tactics of patients with acute cholecystitis.

The purpose of research. Studying of efficiency and safety of pharmacological abortion.
Materials and methods. 200 patients who have chosen a medicamentous method of interruption of undesirable pregnancy of early terms and 50 women of reproductive age, chosen vacuum-aspiration were surveyed.
Results. The given researches confirm that medicamentous abortion is alternative to a surgical method of interruption of pregnancy. Advantages of the given method are: the efficiency which has reached of 95 % at early terms of pregnancy; safety, good tolerance by patients.