The comparative analysis of indices of individually typological constitutional peculiarities of athletes and male teenagers not involved in sport was carried out. The results revealed that athletic trainings do not affect anthropometric indices, Caucasian boys are more advanced than their Mongoloid peers in physical development (p <0,05). Higher prevalence rate of Ketle and Rohrer’s indices at athletes as well as normal BMI and best indicators of heart rate, blood pressure and vital capacity were noted among athletes as compared with the another group .

The analysis of comorbidity of reflux disease and metabolic syndrome at Yakut and Russian population showed that gastroesophageal reflux disease in patients with the metabolic syndrome, regardless of nationality differs by polymorphic clinical course, a higher rate of dyspeptic and extraesophageal symptoms.

The research detected a leptin level at patients with ischemic heart disease subject to the course of stenocardia (stable or instable). We established that destabilization of the IBS course is characterized by elevation of leptin level and increase of a number of its correlation relationship with factors of cardiovascular risk in comparison with patients with stable stenocardia.

The results of 2778 cases of surgical treatment of cholelithiasis are analyzed in this article. The authors detected that the combination of chronic cholelithiasis with diseases of the hepatoduodenopancreatic zone significantly increases risk of performing the laparoscopic cholecystectomy (LCE). High frequency of adhesion is considered as a prime factor, requiring the development of a modified surgical approach. When determining the surgical approach of cholelithiasis treatment in the combination with virus hepatitis it is viable to be guided by immunoenzymometric markers of hepatitis activity. In immunologic inactive forms of virus hepatitis the surgical treatment of cholelithiasis is justified as it restores an appropriate bile outflow and eliminates the inflammatory process. Applying the laparoscopic cholecystectomy at patients with diabetes was justified as well, it preventing obviously the development of destructive forms of cholecystitis.

The features of clinical manifestations of alcoholism among various ethnogeographical groups of the indigenous female population of the Republic of Sakha (Yakutia) are studied. The mortality rate of women due to alcohol abuse amounts from 40,6 to 57,89% and tends to grow. A high-gradient type of the course of alcoholism at women Sakha living in the moderate zone is established. Some biochemical deviations in blood composition at women abusing alcohol are revealed.

Preconditions for implementing fee-based medical services in state budgetary institution of health care and analysis of these services for the last three years are presented.

To define the possibility of application o f SWOT analysis in the social and economic sphere a multi-stage model of SWOT outcome analysis of realization of the Territorial program of state guarantees for the Far East federal district for 2011-2013 has been implemented. The algorithm of a five-stage SWOT analysis is formed by ranking and assessing their interrelation. The results of the work confirmed that due to the flexibility of SWOT analysis it is possible to apply it in various spheres. The application of the multi-stage analysis allows to reveal major and minor factors as well as to carry out the detailed analysis of interrelations between them and to define the further strategy.

The article presents an analysis of the long-term rotavirus infection incidence in children of the Republic Sakha (Yakutia), and a comparison of the age structure of children hospitalized in the Children’s City Clinical Hospital № 2 during the epidemic season 2012-2013. The detection rate of the rotavirus antigen has been identified in patients with symptoms of acute enteric infection as well as the main clinical manifestations of rotavirus gastroenteritis.

On a basis of the analysis of case histories and personal files of tuberculosis patients with HIV-infection in comparison with mono-infected patients with either HIV or tuberculosis for the period 1999-2014 epidemiological assessment of risk factors is presented contributing potentially to the development of mixed forms. The survey shows the following factors as prevalence rate of males and age group 30-39 years, sociallymarginalized or newcomers population, drug addiction, alcohol abuse and smoking as well as staying in penitentiary system and presence of comorbidities.

Medical-social examination of condemned disabled in corrective penal colonies of Federal Penitentiary Service department of the republic of Sakha (Yakutia) (further, FPSD) has been studied, an analysis of condemned people’s disabilities in the Central hospital of FPSD has been conducted and basic causes of disability among the condemned have been established, arrangements for disabled people rehabilitation in the medical colonies of the Republic of Sakha (Yakutia) have been offered.

The analysis according to results of heavy metals accumulation with mercury in fish organs and tissues in freshwater basins of Yakutia was performed. Fishes are bioindicators of basin pollution and a key link of the toxic element coming to human with food chain. The analysis of the data obtained showed 1 to 3 time increase of MPC against the standard in predatory fish - pike and perch, in non-predatory - crucian (carp), roach and dace in the industrial areas of diamond-and gold mining. And these fish species are mostly edible by people.

The study has formulated biomedical and technological requirements for composition, nutrition values ratio and functional drink safety on the basis of local wild berry product Rósa aciculáris with reference to test indicators of actual food of children, adolescents and young people living in the North; a technological scheme of the product’s production has been elaborated. With applying the results of the research technical documentation and product manufacturing specification are elaborated, a check sample is obtained. The product will be recommended in the diet as an additional source of iron, iodine, calcium and other deficiency substances, as an alternative to synthetic fizzy drinks for recovery of the younger generation.

The assessment of content of vitamins and nutrients in a daily ration of natives of Yakutia is shown in this article. The analysis has revealed the low-grade macro and micronutrient content in the ration, especially of such elements as calcium (Ca) and magnesium (Mg), as well as the excess of phosphorus (P) and sodium (Na) in the daily food. The acute deficiency of vitamins B (B1, PP) and C is detected in the analysis of vitamin content of the ration.

In the article a case of verification of brown adipose tissue was described at a patient of 54 years old, a resident of the coldest city in the world Yakutsk. The brown adipose tissue was revealed in adipose tissue samples with para-aortic, perirenal, subclavian and perityroid areas. The abdominal fat was introduced by typical white adipose tissue.

This article shows data of the results of surgical treatment of patients with intraorgnic and extrapancreatic pseudocyst. According to the study the frequency of formation of extrapancreatics pseudocysts is significantly lower that its intraorganic localization. Extrapancreatics pseudocysts differ with scanty clinical presentation and less quantity of complications. X-ray computed tomography with intravenous bolus tracking is considered a ‘gold’ standard of the diagnostics of postnecrotics pseudocysts (especially extraorgans localization). Not complicated extrapancreatics postnecrotics pseudocysts, as usually do not require surgical correction and in complicated process a minimally invasive method of surgical intervention should be applied as the main method of the treatment.

The incidence of ovarian cancer among female population of Primorsky krai for the period 1992-2011 was analyzed. Ovarian cancer was detected to be the 8-th most common type of cancer, occurring more frequently among females of Vladivostok city than among females of Primorsky krai. The ovarian cancer incidence tends to increase over time. By 2017, the ovarian cancer incidence is expected to rise by 16,8–26,6% in Primorsky krai.

The analysis (para-) suicide behavior among population of Yakutsk city from 2010 to 2013 is carried out. Social and clinical characteristics of incomplete suicide cases are determined. The most widespread model of suicidal behavior among the people addressed for medical care is established, as well as basic principles of preventive measures are elaborated.

In this article we presented pathophysiological features of hyperglycemia and its negative effects on the cardiovascular system, the ways to achieve optimal perioperative glycemic control, as well as the results of studies aimed to determine the optimal level of blood glucose for preventing postoperative complications and achieving optimal clinical results.

The limbic system is a complex set of brain structures that support a variety of functions, including sense of smell, instinctive behavior, emotions, memory, sleep, wakefulness and many others. It includes the olfactory bulb, olfactory tract, olfactory trigone, anterior perforated substance, cingulate gyrus, parahippocampal gyrus, dentate gyrus, hippocampus, amygdala, hypothalamus, mammillary body and midbrain reticular formation.
The term “limbic encephalitis” means that the main area affected by inflammation or swelling appeared to be the part of limbic system. The core symptoms are subacute development of cognitive disorders, seizures, impairment of consciousness, sleep disturbances, some psychiatric symptoms (such as depression, irritability, hallucinations) and subacute development of short-term memory deficits. The main causes of limbic encephalitis are autoimmune process (paraneoplastic or non-paraneoplastic) and infections. The paper presents the full etiologybased classification of limbic encephalitis with the description of laboratory and radiologic findings specific for different forms of the disease.

The literature review on implant supported removable prosthetics is presented in this article. Different authors’ views are described concerning the problem of implant - retained denture and its effect on patients’ quality of life, the results of their study are analyzed as well.

There is a review of literature on the themes of: epidemiology, clinic, pathogenesis of inflammatory complications and methods of complex treatment of jaw fractures. Pathogenic mechanisms of the inflammatory process in the area of injury, connected with impaired microcirculation, changes of blood rheology and processes of bone formation are observed. The characteristic of the basic principles of treatment is given. Despite the extensive studies of this problem, posttraumatic complications still remain high, so it is necessary to conduct further researches.

Comparative analysis of applying subclavian catheters (SC) and implantable venous ports (IVP) in children with oncologic diseases is conducted. The study testifies to higher prevalence of IVP as compared with SC. We detected that there are less complications and technical difficulties during installation IVP than SC, so they are subject to correction during operations more frequently. The application of subclavian catheters is accompanied by a higher rate of complications and breakdown of protocols of antitumor treatment as compared with IVP.

The analysis of clinical course of enterovirus infection at children has been carried out. On the base of the Children's city clinical hospital №2 all children underwent the clinical research minimum: complete blood count and clinical urine analysis, throat and nasal swab, including stool sample taken on enterovirus infection. Clinically the enterovirus infection has been detected as herpetic angina with diarrhea and fever. Antiviral drug intake in combination with Cefotaxime (100 mg/kg/day) has manifested good clinical effect.

The results of computer tomography (CT) and magnetic resonance imaging (MRI) of a rare case the analysis of the images is performed and a detailed description of changes on CT and MRI studies is given. This case of aplasia is characterized by symmetrical agenesia of the of bilateral aplasia of cochlea and semicircular canals of the inner ear are presented. In this article cochlea and semicircular canals, and bilateral abnormality of the facial nerve canal, and abnormality of the internal auditory foramen on both sides, as well as unilateral agenesis of the abducent nerve and bilateral agenesis vestibulocochlear nerve. Results of the study indicate a high informative method of CT in the diagnosis of the inner ear abnormalities, as well as the possibility of using MRI in visualizing the cerebellopontine angle for the entire description of its clinical picture.