Clinical manifestations and outcome of hepatitis B
Abstract
A long-term clinical observation of two monozygotic twin brothers with chronic hepatitis was held. Traditional general clinical laboratory tests and ELISA markers of hepatitis were used.
The disease in unvaccinated twins occurred with an interval of 7 years on the background of close home contact. In both brothers acute hepatitis transformed into the chronic form, with the second one - in the shortest terms. Acute hepatitis in the second brother coincides with the peak of the exacerbation of hepatitis in the first.
In this regard, vaccination of persons at risk in outbreak of viral HBV-infection is very important, as well as studying of the genetic properties of the viral agent and the response of microorganism by the help of molecular-genetic methods.
About the Authors
S. I. Semenov
ФГНУ «Институт здоровья»
Russian Federation
Russian Federation
L. D. Indeeva
ЯГКБ
Russian Federation
Russian Federation
N. N. Tikhonova
ЯГКБ
Russian Federation
Russian Federation
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Review
For citations:
Semenov S.I., Indeeva L.D., Tikhonova N.N. Clinical manifestations and outcome of hepatitis B. Yakut Medical Journal. 2010;(1):119-121. (In Russ.)
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