Proteinuria and cardiovascular risk at chronic glomerulonephritis
Abstract
To investigate the role of nephrotic proteinuria in the light of reno-cardiac interactions in chronic glomerulonephritis (CGN) at an early stage of the disease patients with CGN: with a daily proteinuria 3.5 g were under study. All patients underwent clinical examination. In patients with nephrotic proteinuria lower concentrations of Hb, red blood cells, platelets, and total protein in the plasma were revealed. Also they had higher total cholesterol, LDL cholesterol, triglycerides and fibrinogen concentration. In patients with proteinuria the authors found linear increase of the heart size compared to patients with proteinuria < 3.5 g per day. Correlation analysis showed a close negative relationship between left ventricular mass, concentration of Hb and platelet counts, as well as the positive correlation between left ventricular mass and the amount of daily proteinuria in the 2nd group. In patients with CGN, presence of nephrotic proteinuria is associated with increased left ventricular mass and left ventricular cavities.
About the Authors
I. T. Murkamilov
named after I.K. Akhunbaev Kyrgyz State Medical Academy
Kyrgyzstan
Kyrgyzstan
Murkamilov Ilkham Torobekovich – assistant of Department of Therapy of General Practice with a Course of Family Medicine
nephrologist of the 1 qualification category, tel.: 0312 625 690, +996 557 22 19 83
R. Kaliev
named after I.K. Akhunbaev Kyrgyz State Medical Academy
Kyrgyzstan
Kyrgyzstan
Kaliev Rysbek - Doctor of Medical Science, professor, head of Department of General Practice Therapy with a Course of Family Medicine
honored physician of the Kyrgyz Republic, tel.: 0312 625 708. +996 555484879
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For citations:
Murkamilov I.T., Kaliev R. Proteinuria and cardiovascular risk at chronic glomerulonephritis. Yakut Medical Journal. 2013;(3):43-46.
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