Experience of synthetic analogues of somatostatine from esophageal variceal bleeding in patients with hepatic cirrhosis with syndrome of portal hypertension in the multidisciplinary surgical center of RS(Y)
https://doi.org/10.25789/YMJ.2018.62.27
Abstract
The aim of the study was to evaluate the effectiveness of vasoactive therapy with synthetic somatostatin analogues from acute esophageal variceal bleeding in patients with hepatic cirrhosis with portal hypertension syndrome.
Material and methods. The study is based on a retrospective analysis of the results of a comprehensive treatment of 57 patients with cirrhosis and portal hypertension syndrome who were on treatment at the emergency surgical department of the Republican Hospital №2 − the Center for Emergency Medical Care of the Republic of Sakha (Yakutia) in the period from 2015 to 2017.All patients were divided into two groups. The first group consisted of 23 (40,4%) patients, who only used the Sengstaken-Blakemore probe to stop from acute esophageal variceal bleeding. The second group of the study comprised 34 (59,6%) patients who, together with the Sengstaken-Blakemore probe installation, used synthetic somatostatin analogues in complex intensive therapy.
Results.The presented clinical experience of the use of synthetic somatostatin analogues in complex therapy from acute esophageal variceal bleedingto recommend their wide use in the practice of urgent surgical clinics.
Conclusion. The introduction of complex intensive therapy from acute esophageal variceal bleeding in patients with hepatic cirrhosis with the syndrome of portal hypertension of synthetic somatostatin analogues allowed to reduce the overall lethality to 10,7%, and to reduce the risk of rebleeding by 17%.
About the Authors
V. V. Saveliev
FGAOU VO «North-Eastern Federal University named after M.K. Ammosov
Russian Federation
Russian Federation
Savelyev Vyacheslav Vasilievich - MD, Professor of the Department of Faculty Surgery, Urology, Oncology and
Otorhinolaryngology
677000, Yakutsk, ul. Belinsky, 58
Phone: 8 (4112) 35-20-90, fax: 8 (4112) 32-13-14
M. M. Vinokurov
FGAOU VO «North-Eastern Federal University named after M.K. Ammosov
Russian Federation
Russian Federation
Vinokurov Mikhail Mikhailovich - MD, Professor, Head of the Department of Faculty Surgery, Urology, Oncology and
Otorhinolaryngology
677000, Yakutsk, st. Dzerzhinsky 41, apt. 26
Phone: 8 (4112) 35-20-90, fax: 8 (4112) 32-13-14
V. P. Egorova
FGAOU VO «North-Eastern Federal University named after M.K. Ammosov
Russian Federation
Russian Federation
Egorova Varvara Prokopievna - postgraduate student of the Department of Faculty Surgery, Urology, Oncology
and Otorhinolaryngology
677000, Yakutsk, st. Dzerzhinsky 41/3, apt. 114
Phone: 8 (4112) 35-20-90, fax: 8 (4112) 32-13-14
T. V. Yalynskaya
FGAOU VO «North-Eastern Federal University named after M.K. Ammosov
Russian Federation
Russian Federation
Yalynskaya Tatyana Vadimovna - clinical resident of the Department of Surgical Diseases and Dentistry of the
Faculty of Postgraduate Education of Physicians
677009, Yakutsk, st. Dzerzhinsky 45/2, apt. 70
Phone: 8 (4112) 35-20-90, fax: 8 (4112) 32-13-14
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Review
For citations:
Saveliev V.V., Vinokurov M.M., Egorova V.P., Yalynskaya T.V. Experience of synthetic analogues of somatostatine from esophageal variceal bleeding in patients with hepatic cirrhosis with syndrome of portal hypertension in the multidisciplinary surgical center of RS(Y). Yakut Medical Journal. 2018;(2):90-92. https://doi.org/10.25789/YMJ.2018.62.27
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