Features of the microelemental status at anemia in pregnant women
https://doi.org/10.25789/YMJ.2019.68.15
Abstract
A comprehensive clinical and laboratory research of women from the Amur region was carried on during and after their pregnancy. The environment in the Amur region is characterized by low level of I, Se, high content of Mn, Fe, Zn and an imbalance of other trace elements. Research showed an increased amount of Cu in serum and decreased amount of Cu in blood cells. In anemia, regardless of the level of Fe, there was a decrease in Co, Se in serum and an increase in Mn in blood cells. The distinctive features of microelement status for iron deficiency anemia – an increased Mn in blood serum; for iron-saturated anemia – increased Li in serum, increased Li and Co in blood cells were determined.
About the Authors
S. V. Suprun
Far Eastern Scientific Center of Physiology and Pathology of Respiration – Khabarovsk Branch of Research Institute of Maternity and Childhood Protection
Russian Federation
Russian Federation
Suprun Stefaniya Viktorovna – Doctoral Degree in Medicine, Main staff scientist of Groups of health and environmental problems of mother and child health
Khabarovsk
O. N. Morozova
Far Eastern Scientific Center of Physiology and Pathology of Respiration – Khabarovsk Branch of Research Institute of Maternity and Childhood Protection
Russian Federation
Russian Federation
Morozova Olga Nikolaevna – Researcher of Groups of health and environmental problems of mother and child health, obstetrician-gynecologist
Khabarovsk
V. K. Kozlov
Far Eastern Scientific Center of Physiology and Pathology of Respiration – Khabarovsk Branch of Research Institute of Maternity and Childhood Protection
Russian Federation
Russian Federation
Kozlov Vladimir Kirillovich – Doctoral Degree in Medicine, Corresponding Member of RAS, Main staff scientist of Groups of health and environmental problems of mother and child health
Khabarovsk
O. A. Lebed'ko
Far Eastern Scientific Center of Physiology and Pathology of Respiration – Khabarovsk Branch of Research Institute of Maternity and Childhood Protection
Russian Federation
Russian Federation
Lebed'ko Olga Antonovna – Doctoral Degree in Medicine, Director Research Institute of Maternity and Childhood Protection, Senior Researcher Laboratory of Integral Methods of Bronchopulmonary and Perinatal Pathology Research
Khabarovsk
References
1. Gromova O.A. Analysis of molecular mechanisms of influence of iron, copper, manganese in the pathogenesis of iron deficiency anemia / O.A. Gromova, I. Yu. Torshin, A.K. Hadzhidis. https://medi.ru/info/5757/-2010
2. Microelementosis of a person: etiology, classification, organopathology / A. P. Avtsyn, A.A. Zhavoronkov, M. A. Rish, L. S. Struchkovа. – M.: Medicine, 1991. – 496 p.
3. Berti C. Micronutrients in pregnancy: Current knowledge and unresolved questions / C. Berti, H.K. Biesalski, R. Gärtner // Clin. Nutr. – 2011. – №30. – P.689-701.
4. Spencer Briohny H. Essentiality of Trace Element Micronutrition in Human Pregnancy: A Systematic Review / Briohny H Spencer, Jessica J Vanderlelie, Anthony V Perkins // Journal of Pregnancy and Child Health. – 2015. – 2:3. DOI: 10.4172/2376-127X.1000157.
5. Daily oral iron supplementation during pregnancy / J.P. Peña-Rosas, L.M. De-Regil, M.N. Garcia-Casal, T. Dowswell // Cochrane Database Syst Rev. 2015 Jul 22;(7):CD004736. doi: 10.1002/14651858.CD004736.pub5.
6. Darnton-Hill I. Micronutrients in Pregnancy in Low and Middle Income Countries / I. Darnton-Hill, C.M. Uzonna // Nutrients. – 2015. – Vol. 7. – P. 1744–1768
7. Varsi Kristin. Maternal selenium status during pregnancy and clinical outcome in the infant / Kristin Varsi, Bjørn Bolann, Anne-Lise Bjørke-Monsen // Journal of Trace Elements in Medicine and Biology. – 2017; 41(1): 4.
8. Maternal BMI during Pregnancy: Effect on trace elements Status and Pregnancy Outcomes / Emmanuel I Ugwuja, Emmanuel I Akubugwo, Onyechi Obidoa, Ama U Ibiam // International Journal of Health Research. – June 2010; 3(2): 71-78
9. Aschner Michael. Manganese-induced neurotoxicity: Lessons from worms to human neonates / Michael Aschner // Journal of Trace Elements in Medicine and Biology. – 2017; 41(1): 10.
10. Trace elements and cell membranes at pregnancy / S.V. Suprun, G.P. Evseeva, T.N. Larina, O.S. Kudryashova // Journal of Trace Elements in Medicine and Biology. – 2017; 41(1): 21
11. WHO. Guideline: Daily iron and folic acid supplementation in pregnant women. Geneva, World Health Organization, 2017
12. World Medical Association Declaration of Helsinki Ethical Principles for Medical Research Involving Human Subjects, 64th General Assembly, Fortaleza, Brazil, October, 2013.
Review
For citations:
Suprun S.V., Morozova O.N., Kozlov V.K., Lebed'ko O.A. Features of the microelemental status at anemia in pregnant women. Yakut Medical Journal. 2019;(4):58-60. https://doi.org/10.25789/YMJ.2019.68.15
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