<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.3 20210610//EN" "JATS-journalpublishing1-3.dtd">
<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">ymj</journal-id><journal-title-group><journal-title xml:lang="ru">Якутский медицинский журнал</journal-title><trans-title-group xml:lang="en"><trans-title>Yakut Medical Journal</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1813-1905</issn><issn pub-type="epub">2312-1017</issn><publisher><publisher-name>ЯНЦ КМП</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.25789/YMJ.2019.68.15</article-id><article-id custom-type="elpub" pub-id-type="custom">ymj-1207</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ГИГИЕНА, САНИТАРИЯ, ЭПИДЕМИОЛОГИЯ И МЕДИЦИНСКАЯ ЭКОЛОГИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>HYGIENE, SANITATION, EPIDEMIOLOGY AND MEDICAL ECOLOGY</subject></subj-group></article-categories><title-group><article-title>Особенности микроэлементного статуса при анемиях у беременных женщин</article-title><trans-title-group xml:lang="en"><trans-title>Features of the microelemental status at anemia in pregnant women</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-6724-3654</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Супрун</surname><given-names>С. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Suprun</surname><given-names>S. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Супрун Стефания Викторовна – д.м.н., гл.н.с.</p></bio><bio xml:lang="en"><p>Suprun Stefaniya Viktorovna – Doctoral Degree in Medicine, Main staff scientist of Groups of health and environmental problems of mother and child health</p><p>Khabarovsk</p></bio><email xlink:type="simple">evg-suprun@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-0355-6963</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Морозова</surname><given-names>О. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Morozova</surname><given-names>O. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Морозова Ольга Николаевна – м.н.с.</p></bio><bio xml:lang="en"><p>Morozova Olga Nikolaevna – Researcher of Groups of health and environmental problems of mother and child health, obstetrician-gynecologist</p><p>Khabarovsk</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-9978-1043</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Козлов</surname><given-names>В. К.</given-names></name><name name-style="western" xml:lang="en"><surname>Kozlov</surname><given-names>V. K.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Козлов Владимир Кириллович – чл.-корр. РАН, д.м.н., гл.н.с.</p></bio><bio xml:lang="en"><p>Kozlov Vladimir Kirillovich – Doctoral Degree in Medicine, Corresponding Member of RAS, Main staff scientist of Groups of health and environmental problems of mother and child health</p><p>Khabarovsk</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-8855-7422</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Лебедько</surname><given-names>О. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Lebed'ko</surname><given-names>O. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Лебедько Ольга Антоновна – д.м.н., директор, зав. лаб.</p></bio><bio xml:lang="en"><p>Lebed'ko Olga Antonovna – Doctoral Degree in Medicine, Director Research Institute of Maternity and Childhood Protection, Senior Researcher Laboratory of Integral Methods of Bronchopulmonary and Perinatal Pathology Research</p><p>Khabarovsk</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru">Хабаровский филиал ДНЦ ФПД – НИИОМиД<country>Россия</country></aff><aff xml:lang="en">Far Eastern Scientific Center of Physiology and Pathology of Respiration – Khabarovsk Branch of Research Institute of Maternity and Childhood Protection<country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2019</year></pub-date><pub-date pub-type="epub"><day>29</day><month>08</month><year>2025</year></pub-date><volume>0</volume><issue>4</issue><fpage>58</fpage><lpage>60</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Супрун С.В., Морозова О.Н., Козлов В.К., Лебедько О.А., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Супрун С.В., Морозова О.Н., Козлов В.К., Лебедько О.А.</copyright-holder><copyright-holder xml:lang="en">Suprun S.V., Morozova O.N., Kozlov V.K., Lebed'ko O.A.</copyright-holder><license license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://ymj.elpub.ru/jour/article/view/1207">https://ymj.elpub.ru/jour/article/view/1207</self-uri><abstract><p>Проведено комплексное клинико-лабораторное обследование женщин во время и вне беременности, проживающих в условиях Приамурья с низким содержанием I, Se, повышенным содержанием Mn, Fe, Zn и дисбалансом других микроэлементов в окружающей среде. У всех наблюдаемых женщин выявлены повышение Cu в сыворотке и снижение в форменных элементах крови. При анемиях независимо от уровня Fe отмечались снижение Co, Se в сыворотке и повышение Mn в клетках крови. Определены отличительные особенности микроэлементного статуса для железодефицитных анемий – это повышение Mn в сыворотке крови; для железонасыщенных анемий – повышение в сыворотке Li, в форменных элементах – Li и Co.</p></abstract><trans-abstract xml:lang="en"><p>A comprehensive clinical and laboratory research of women from the Amur region was carried on during and after their pregnancy. The environment in the Amur region is characterized by low level of I, Se, high content of Mn, Fe, Zn and an imbalance of other trace elements. Research showed an increased amount of Cu in serum and decreased amount of Cu in blood cells. In anemia, regardless of the level of Fe, there was a decrease in Co, Se in serum and an increase in Mn in blood cells. The distinctive features of microelement status for iron deficiency anemia – an increased Mn in blood serum; for iron-saturated anemia – increased Li in serum, increased Li and Co in blood cells were determined.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>беременные женщины</kwd><kwd>микроэлементы</kwd><kwd>анемия</kwd></kwd-group><kwd-group xml:lang="en"><kwd>pregnant women</kwd><kwd>trace elements</kwd><kwd>anemia</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Громова О.А. Анализ молекулярных механизмов воздействия железа, меди, марганца в патогенезе железодефицитной анемии / О.А. Громова, И.Ю. Торшин, А.К. Хаджидис. https://medi.ru/info/5757/-2010</mixed-citation><mixed-citation xml:lang="en">Gromova O.A. Analysis of molecular mechanisms of influence of iron, copper, manganese in the pathogenesis of iron deficiency anemia / O.A. Gromova, I. Yu. Torshin, A.K. Hadzhidis. https://medi.ru/info/5757/-2010</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Микроэлементозы человека: этиология, классификация, органопатология / А.П.Авцын, А.А. Жаворонков, М.А. Риш, Л.С. Строчкова. – М.: Медицина, 1991. - 496 с.</mixed-citation><mixed-citation xml:lang="en">Microelementosis of a person: etiology, classification, organopathology / A. P. Avtsyn, A.A. Zhavoronkov, M. A. Rish, L. S. Struchkovа. – M.: Medicine, 1991. – 496 p.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Berti C. Micronutrients in pregnancy: Current knowledge and unresolved questions / C. Berti, H.K. Biesalski, R. Gärtner // Clin. Nutr. – 2011. – №30. – P.689-701.</mixed-citation><mixed-citation xml:lang="en">Berti C. Micronutrients in pregnancy: Current knowledge and unresolved questions / C. Berti, H.K. Biesalski, R. Gärtner // Clin. Nutr. – 2011. – №30. – P.689-701.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Spencer Briohny H. Essentiality of Trace Element Micronutrition in Human Pregnancy: A Systematic Review / Briohny H Spencer, Jessica J Vanderlelie, Anthony V Perkins // Journal of Pregnancy and Child Health. – 2015. – 2:3. DOI: 10.4172/2376-127X.1000157.</mixed-citation><mixed-citation xml:lang="en">Spencer Briohny H. Essentiality of Trace Element Micronutrition in Human Pregnancy: A Systematic Review / Briohny H Spencer, Jessica J Vanderlelie, Anthony V Perkins // Journal of Pregnancy and Child Health. – 2015. – 2:3. DOI: 10.4172/2376-127X.1000157.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Daily oral iron supplementation during pregnancy / J.P. Peña-Rosas, L.M. De-Regil, M.N. Garcia-Casal, T. Dowswell // Cochrane Database Syst Rev. 2015 Jul 22;(7):CD004736. doi: 10.1002/14651858.CD004736.pub5.</mixed-citation><mixed-citation xml:lang="en">Daily oral iron supplementation during pregnancy / J.P. Peña-Rosas, L.M. De-Regil, M.N. Garcia-Casal, T. Dowswell // Cochrane Database Syst Rev. 2015 Jul 22;(7):CD004736. doi: 10.1002/14651858.CD004736.pub5.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Darnton-Hill I. Micronutrients in Pregnancy in Low and Middle Income Countries / I. Darnton-Hill, C.M. Uzonna // Nutrients. – 2015. – Vol. 7. – P. 1744–1768</mixed-citation><mixed-citation xml:lang="en">Darnton-Hill I. Micronutrients in Pregnancy in Low and Middle Income Countries / I. Darnton-Hill, C.M. Uzonna // Nutrients. – 2015. – Vol. 7. – P. 1744–1768</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Varsi Kristin. Maternal selenium status during pregnancy and clinical outcome in the infant / Kristin Varsi, Bjørn Bolann, Anne-Lise Bjørke-Monsen // Journal of Trace Elements in Medicine and Biology. – 2017; 41(1): 4.</mixed-citation><mixed-citation xml:lang="en">Varsi Kristin. Maternal selenium status during pregnancy and clinical outcome in the infant / Kristin Varsi, Bjørn Bolann, Anne-Lise Bjørke-Monsen // Journal of Trace Elements in Medicine and Biology. – 2017; 41(1): 4.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Maternal BMI during Pregnancy: Effect on trace elements Status and Pregnancy Outcomes / Emmanuel I Ugwuja, Emmanuel I Akubugwo, Onyechi Obidoa, Ama U Ibiam // International Journal of Health Research. – June 2010; 3(2): 71-78</mixed-citation><mixed-citation xml:lang="en">Maternal BMI during Pregnancy: Effect on trace elements Status and Pregnancy Outcomes / Emmanuel I Ugwuja, Emmanuel I Akubugwo, Onyechi Obidoa, Ama U Ibiam // International Journal of Health Research. – June 2010; 3(2): 71-78</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Aschner Michael. Manganese-induced neurotoxicity: Lessons from worms to human neonates / Michael Aschner // Journal of Trace Elements in Medicine and Biology. – 2017; 41(1): 10.</mixed-citation><mixed-citation xml:lang="en">Aschner Michael. Manganese-induced neurotoxicity: Lessons from worms to human neonates / Michael Aschner // Journal of Trace Elements in Medicine and Biology. – 2017; 41(1): 10.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Trace elements and cell membranes at pregnancy / S.V. Suprun, G.P. Evseeva, T.N. Larina, O.S. Kudryashova // Journal of Trace Elements in Medicine and Biology. – 2017; 41(1): 21</mixed-citation><mixed-citation xml:lang="en">Trace elements and cell membranes at pregnancy / S.V. Suprun, G.P. Evseeva, T.N. Larina, O.S. Kudryashova // Journal of Trace Elements in Medicine and Biology. – 2017; 41(1): 21</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">WHO. Guideline: Daily iron and folic acid supplementation in pregnant women. Geneva, World Health Organization, 2017</mixed-citation><mixed-citation xml:lang="en">WHO. Guideline: Daily iron and folic acid supplementation in pregnant women. Geneva, World Health Organization, 2017</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">World Medical Association Declaration of Helsinki Ethical Principles for Medical Research Involving Human Subjects, 64th General Assembly, Fortaleza, Brazil, October, 2013.</mixed-citation><mixed-citation xml:lang="en">World Medical Association Declaration of Helsinki Ethical Principles for Medical Research Involving Human Subjects, 64th General Assembly, Fortaleza, Brazil, October, 2013.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
