The purpose of research. An estimation of infl uence of the dust allocated at processing of diamonds on a peroxide oxidation condition and an immune fabric in the experimental animals.
Material and methods. The biomaterial of 80 he-rats of a line “Wistar”, placed on 30 days in workshop of a facet of diamonds is investigated. The lipid peroxide oxidation intensity and parameters of antioxidant status are defi ned by a spectrophotometric method. Phagocytic activity of leukocytes is certained by means of NBT- test. The morphological analysis is held by a method of a lightoptical microscopy. The chemical compound of the dustsweeps is certained by the atom-emissive method with an inductive connected plasma.
Results. Lipid peroxide oxidation intensity in the experimental animals was authentically higher in 1,7 times, than in the intact animals. SOD activity tended to decrease, and concentration of lowmolecular antioxidants - to increase. The morphofunctional analysis and NBT - test testify to suppression of functional activity of immune structures of trachea and bronchial tubes of all generations and suppression of nonspecifi c cellular immunity.
The conclusion. Experimental researches testify to adverse infl uence of a diamond dust on a condition of immune and antioxidatic protection of an organism of animals (rats). Diamond dust cytotoxity on an organism is caused by structure of the aerosols formed from diamond nanoparticles and carbides of heavy metals.

Results of diagnostics and treatment of 338 patients with chronic erosion of a stomach are listed. Plural (more than 5) erosions have been revealed in 226 (66,9 %), singular - in 112 (33,1 %) patients. Patients with plural erosions received the conservative treatment including inhibitors of a proton pomp, prokinetics, antacids, antihelicobacter - therapy. The patients with singular erosions on the first stage were treated conservatively. Having no effect from conservative treatment to 83 (74,1%) patients endoscopic resection of the erosed mucous was carried out.. Efficiency of operation in more than 3 years period has made 91,1 %. The quantity of patients with attributes of inflammation, edema, neutrophil or mononuclear infiltration has decreased from 75,9 % in early terms after resection of mucous to 67,1 and 7,6 % in the nearest and remote terms accordingly. The received direct and remote results of treatment justify chosen tactics in therapy of chronic stomach erosion.

The analysis of the treatment results of 782 patients with stomach ulcer (239), duodenum (488), and also patients with the combined ulcers (37) and gastroenteroanastomosis peptic ulcer (18), complicated with bleeding, has been held. 5,9% of patients were operated in the emergency order and 16,4% patients from the all with bleedings were operated quickly. In the delayed and scheduled order operative treatment is lead at 21,7 % of patients. Postoperational lethal outcome was 3,8%. Complications after operation took place at 12,2 % of patients. We consider, that in treatment of ulcer gastroduodenal bleedings it is necessary to adhere to the individual active-waiting tactics based on a somatic condition of the patient, duration of the ulcer anamnesis and localization of ulcer, presence of gastroduodenal bleeding episodes in the past, and also intensity of bleeding (according J.Forrest) and effi ciency of a conservative hemostasis.

The efficiency of different surgical policies was comparatively evaluated in 76 patients with infectious forms of pancreatic necrosis treated at a clinic in 2000 to 2006. The baseline use of a stepwise method of necrotic seguestrectomies, which included a programmed mode of stepwise revisions and sanitations of the retroperitoneal space and abdomen in combination with «open» drainages in patients with various pancreatogenic infections versus routine surgical treatmens for pancreatic necrosis.

The purpose of research. To study dynamics and to fi nd out the populational and time laws of colorectal morbidity in various groups of the population of Yakutia and to make their prognosis.
Material and methods. The statistical material, containing 27,3 thousand cases of malignant neoplasms is analysed. In 2098 (7,7 %) cases there was revealed a cancer of the colorectal localization, including cancer of colon in 1 202 (57,3 %) patients and cancer of rectum in 896 (42,7 %). Concept of the given localization morbidity in republic is received by means of the intensive and standardized parameters (SP). Age distribution of the population of 24 countries of the world reckoning 100 thousand (world standard) was taken for the standard.
Results of research. Persons of the both gender in the age elder 40 are exposed to colon cancer. SP of colon cancer morbidity in the urban population has made 11,3±1,1, cancer of rectum - 8,5±0,90/0000. In the agricultural population accordingly - 8,0±0,9 and 5,8±0,7. To 2010 colon cancer will make predicted levels of morbidity in the indigenous population 9,1, in the non-indigenous population - 15,50/0000, cancer of rectum - 9,3 and 14,30/0000 accordingly.
The conclusion. Colorectal cancer in structure of oncological morbidity of the population in conditions of the Far North has high parameters with the tendency to the further growth and keeps age, ethnic and territorial conditionality. The given pathology more often inherent in the persons of not indigenous nationality living in cities and, mainly, in the age category elder 50 years.

The purpose of research. Development and introduction in practice of new smallinvasive method of diagnostics and operative treatment at sharp diseases of scrotum in children.
Materials and methods. Experience of diagnostics, treatment and studying of outcomes is put into basis of research in 16 patients in the age of from 4 till 15 years with the diagnosis: a syndrome of hydropic scrotum.
Conclusions. The offered technique of scrotoscopy allows to execute all necessary diagnostic and medical manipulations for liquidation of disease with minimal traumatisation, that will improve quality of treatment.

We report the results of modifi ed direct method of M.tuberculosis drug susceptibility testing in 70 patients with newly identifi ed moderate to heavy bacterioexcretion using a microscopic technique. Test techniques under assessment were the described direct method and indirect absolute concentration method. Agreement in 100% of cases was found in test results of susceptible strains. In resistant strains, agreement between compared test techniques was 89.3%, 88.9%, 90.5%, and 81.8% for strains resistant to streptomycin, isoniazid, rifampycin and kanamycin, respectfully. Furthermore, high agreement rate of test results (94.1%) was observed in multidrug-resistant strains, while the time of drug susceptibility assessment reduced to 22-24 days. The described method is low-cost and is available for all kinds of laboratories. The method received a patent of Russian Federation (no. 2244927).

The purpose of research. Studying of features of arterial pressure in children of different ethnic groups of Republic Sakha (Yakutia).
Materials and methods. Practically healthy 757 children of migrants and children of indigenous nationalities of republic were investigated. By results of inspection anthopometry, measurements of arterial pressure, gathering of the anamnesis and defi nition of a threshold of fl avouring sensitivity to table salt in children of various ethnic groups in different areas of residing (tundra, the river, city), an estimation of connection of the chosen characteristics with an ethnic belonging and with area of residing, an estimation of connection of a threshold of sensitivity to table salt with elements of structure of heart rhythm were lead.
Results. The comparative estimation of parameters of arterial pressure lead by us in children of indigenous nationalities (Evens, Evenks, Chukchi, Yukaghirs, Dolgans) and children of migrants (Sakha and Russian) ascertains the fact of presence of authentic distinctions of values of systolic and diastolic arterial pressure in children of indigenous nationalities in the majority of age groups and absence of such distinctions in children of migrants, long living in Republic Sakha (Yakutia). Distinctions of a threshold of fl avouring sensitivity to table salt in children of different ethnic groups of Republic Sakha (Yakutia), which were investigated by nobody earlier, were described.