Transfusion of donor platelets

   The article summarizes recent data on the safety and efficacy of preparation and transfusion of donor platelets. There are discussed the features of a) the recruitment and selection of donors; b) the advantages and disadvantages of different methods of platelet concentrates production; c) platelet concentrates inventory management; d) immunological and infectious safety of platelet concentrates; e) deal with undesired constituents remaining in platelet concentrates. There are made the practical recommendations for better choice of platelet concentrate for patient safety. In conclusion, it is noted that in Russia should be normalized timing for: buffy-coat isolation and pooling, platelet concentrate leukodepletion, as well as a gradual transition to 100 % transfusion of pathogen-reduced platelet concentrates.

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