Assessment of neurological deficit scale for ischemic stroke in early childhood
https://doi.org/10.1234/YMJ.2022.77.12
Abstract
The article discusses the data of an original study on development of a clinical scale for neurological deficits severity assessing in children with arterial ischemic strokes (AIS) under the age of 2 years old (SANDYc). The relevance of SANDYc development is caused by inability to use pedNIHSS scale in children under 2 years of age and limitations of the PSOM using in the acute and subacute IS stages in young children. The study presents clinical features of IS course in 31 children aged up to 2 years old, being treated at children's clinical hospital N5 named after N.F. Filatova from 2005 to 2021. The statistical analysis data are presented, showing statistically significant correlations between the assessment results according to SANDYc and the values obtained according to the PSOM and BMRC scales. Additionally, statistical analysis demonstrated correlation between allelic variants A / C and C / C of the MTHFR A1298C gene (p = 0.044) in the examined children and milder clinical course of AIS as assessed by SANDYc.
About the Authors
A. V. Minin
St. Petersburg State Pediatric Medical University of the Ministry of Healthcare of the Russian Federation
Russian Federation
Russian Federation
Alexey V. Minin – M.D., Ph.D, Associate Professor of Neonatology Department (with courses in Neurology and Obstetrics-Gynecology), Faculty of Postgraduate and Additional Professional Education, St. Petersburg State Pediatric Medical University of the Ministry of Healthcare of the Russian Federation.
A. B. Palchik
St. Petersburg State Pediatric Medical University of the Ministry of Healthcare of the Russian Federation
Russian Federation
Russian Federation
Alexander B. Palchik – M.D., Ph.D, Professor of Neonatology Department (with courses in Neurology and Obstetrics-Gynecology), Faculty of Postgraduate and Additional Professional Education, St. Petersburg State Pediatric Medical University of the Ministry of Healthcare of the Russian Federation.
К. I. Pshenichnaya
St. Petersburg State Pediatric Medical University of the Ministry of Healthcare of the Russian Federation
Russian Federation
Russian Federation
Ksenia I. Pshenichnaya – M.D., Ph.D, Professor of Pediatrics, Endocrinology and Abilitology Department, Faculty of Postgraduate and Additional Professional Education, St. Petersburg State Pediatric Medical University of the Ministry of Healthcare of the Russian Federation.
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Review
For citations:
Minin A.V., Palchik A.B., Pshenichnaya К.I. Assessment of neurological deficit scale for ischemic stroke in early childhood. Yakut Medical Journal. 2022;(1):44-49. https://doi.org/10.1234/YMJ.2022.77.12
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