Evaluation of antitumor activity of benzimidazole derivative on models of experimental tumors

The effect of dihydrobromide-2-(3,4-dihydroxyphenyl)-9-diethylamino-ethylimidazo-[1,2-a] benzimidazole on the growth and metastasis of transplanted allografts of melanoma B16 and epidermoid lung carcinoma Lewis with intraperitoneal administration was investigated. The antitumor effect was established in relation to primary epidermoid lung carcinoma by Lewis and its metastases to the lungs, as well as in relation to metastatic lung damage for melanoma B16 mice.

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