Brain neurotrophic BDNF level at teenagers with syncopal conditions
https://doi.org/10.25789/YMJ.2020.70.27
Abstract
We determined the level of brain neurotrophic factor BDNF in plasma of adolescents aged 12-17 with syncopal conditions. Lower BDNF levels in plasma were found in a large number of adolescents examined. Taking into account the significant role of BDNF in the modulation of neuroplastic processes, the revealed decrease in its level can probably be regarded as a metabolic marker of the risk of neurodegenerative processes appearance and presence in brain tissue of adolescents with recurrent syncope. This assumption can be confirmed by further studies. Conclusions: syncopal conditions in adolescents are associated with a lower content of brain neurotrophic factor BDNF. In adolescents with syncopal conditions, there are more individuals with slightly or significantly lower BDNF compared to the group without syncope.
About the Authors
Yu. R. Akhmel'dinova
KrasGMU
Russian Federation
Russian Federation
Akhmel'dinova Yuliya Rinatovna - 6th year student of the pediatric faculty
660022, Krasnoyarsk, ul. Partizan Zheleznyak, 1
L. S. Evert
Research Institute of the Ministry of Railways, FIC KSC SB RAS;
HE "KSU named after N.F. Katanova"
Russian Federation
Russian Federation
Evert Lidiya Semenovna - Doctor of Medical Sciences, Chief Researcher at the Clinical Department of Somatic and Mental Health of Children
660022, Krasnoyarsk, ul. Partizan Zheleznyak, d. 3G;
Professor of the Department of General Professional Disciplines FSBEI
655000, Abakan, ul. Khakasskaya, 68
T. V. Potupchik
FSBEI HE “KrasGMU named after prof. V.F. Voyno-Yasenetsky" Ministry of Health of the Russian Federation
Russian Federation
Russian Federation
Potupchik Tat'yana Vital'evna - candidate of medical sciences, associate professor of the Department of Pharmacology and Pharmaceutical Consulting with a course
660022, Krasnoyarsk, st. Partizan Zheleznyak, d.1
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Review
For citations:
Akhmel'dinova Yu.R., Evert L.S., Potupchik T.V. Brain neurotrophic BDNF level at teenagers with syncopal conditions. Yakut Medical Journal. 2020;(2):92-95. https://doi.org/10.25789/YMJ.2020.70.27
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