Photoperiodic variation of thyroid hormones and autoantibodies in males of the European North
https://doi.org/10.25789/YMJ.2020.70.23
Abstract
In this paper we presented the results of the study of an annual variation of thyroid hormones and autoantibodies in 20 healthy men. There were shown the significant intra-annual rhythms of the total iodothyronines levels with lower values in the autumn-winter period. The annual variation in serum antibodies to thyroid peroxidase showed a significant increase in antibody levels in the autumn-winter period compared to the spring one. The levels of thyroglobulin, a marker of thyroid activity, were statistically significantly higher in the spring compared to the autumn.
Keywords
thyroglobulin antibodies,
thyroid peroxidase antibodies,
thyroid stimulating hormone,
thyroglobulin,
thyroxine,
triiodothyronine,
photoperiodicity
Supporting agencies: The reported study was funded by the FCIARctic according to the research project: “Elucidation of the modulating effect of the catecholamine levels on the hormonal profile in humans and aquatic organisms of the European North” (АААА-А19-119120990060-0).
About the Authors
I. N. Molodovskaya
N. Laverov Federal Center for Integrated Arctic Research
Russian Federation
Russian Federation
Molodovskaya Irina Nikolaevna – candidate of biological sciences, scientific researcher
163000, Archangelsk, Lomonosova av. 249
+79115550701
E. V. Tipisova
N. Laverov Federal Center for Integrated Arctic Research
Russian Federation
Russian Federation
Tipisova Elena Vasilievna – doctor of biological sciences, chief researcher
163000, Archangelsk, Lomonosova av. 249
+79095555095
V. A. Popkova
N. Laverov Federal Center for Integrated Arctic Research
Russian Federation
Russian Federation
Popkova Victoria Anatolievna – candidate of biological sciences, senior researcher
163000, Archangelsk, Lomonosova av. 249
+79216754501
A. E. Elfimova
N. Laverov Federal Center for Integrated Arctic Research
Russian Federation
Russian Federation
Elfimova Alexandra Eduardovna – candidate of biological sciences, senior researcher
163000, Archangelsk, Lomonosova av. 249
+79217209022
D. S. Potutkin
N. Laverov Federal Center for Integrated Arctic Research
Russian Federation
Russian Federation
Potutkin Dmitry Sergeevich – junior researcher
163000, Archangelsk, Lomonosova av. 249
+79021981974
References
1. Barabash L.V. To the question of diagnostic criteria perfection in view circannual variation of organism functioning adaptive systems in conditions of Western Siberia / L.V. Barabash, Ye.F. Levitsky, S.V. Kremeno // Bulletin of Siberian Medicine. – 2015. – V. 14. – № 3. – P. 10-17.
2. Gorenko I.N. Thyroid antibodies levels in euthyroid men and women - residents of the Arctic Zone of the Russian Federation / I.N. Gorenko // Klinicheskaya Laboratornaya Diagnostika. – 2019. – V. 64 (9). – P. 541-545. doi: 10.18821/0869-2084-2019-64-9-541-545.
3. Lutfalieva G.T. Autoantibodies' role in adaptive mechanisms of regulation of functional activity of thyroid hormone and thyrotropin hormone of hypophisis in northern inhabitants / G.T. Lutfalieva, T.S. Churkina // Human Ecology. – 2010. – № 10. – P. 33-36.
4. Prokhorova E.M. Biological rhythms and health / E.M. Prokhorova// Service PLUS. – 2010. – № 3. – P. 20-26.
5. Ramenskaya E.B. The influence of seasonality and photoperiodism on the hormonal profile of the inhabitants of the North / E.B. Ramenskaya // Adaptation and body resistance in the North (physiological and biochemical mechanisms). – Syktyvkar, 1990. – P. 35-41.
6. Circannual pattern of hypothalamic-pituitary-thyroid (HPT) function and mood during extended antarctic residence / L.A. Palinkas, H.L. Reed, K.R. Reedy [et al.] // Psychoneuroendocrinology. – 2001. – V. 26. – № 4. – P. 421-431. DOI: 10.1016/s0306-4530(00)00064-0.
7. Effect of seasonal changes on the transition between subclinical hypothyroid and euthyroid status / T.H. Kim, K.W. Kim, H.Y. Ahn [et al.] // J Clin Endocrinol Metab. – 2013. – V. 98. – № 8. – P. 3420-3429. DOI: 10.1210/jc.2013-1607.
8. Elevation in serum thyroglobulin during prolonged Antarctic residence: effect of thyroxine supplement in the polar 3, 5, 3-triiodothyronine syndrome / N.V. Do, L. Mino, G.R. Merriam [et al.] // J Clin Endocrinol Metab. – 2004. – V. 89. – № 4. – P. 1529-1533. DOI: 10.1210/jc.2003-031747.
9. Environmental influences on hypothalamic-pituitary-thyroid function and behavior in Antarctica / L.A. Palinkas, K.R. Reedy, M. Shepanek [et al.] // Physiol Behav. – 2007. – V. 92. – № 5. – P. 790-799. DOI: 10.1016/j.physbeh.2007.06.008.
10. Is the serum thyroglobulin response to recombinant human thyrotropin sufficient, by itself, to monitor for residual thyroid carcinoma? / R.J. Robbins, J.T. Chon, M. Fleisher [et al.] // J Clin Endocrinol Metab. – 2002. – V. 87. – P. 3242-3247. DOI: 10.1210/jcem.87.7.8702.
11. Nelson R.J. Seasonal changes in immune function / R.J. Nelson, G.E. Demas // Q Rev Biol. – 1996. – V. 71(4). – P. 511-548. DOI: 10.1086/419555.
12. New reference intervals for thyrotropin and thyroid hormones based on National Academy of Clinical Biochemistry criteria and regular ultrasonography of the thyroid / J. Kratzsch, G.M. Fiedler, A. Leichtle [et al.] // Clin Chem. – 2005. – V. 51. – № 8. P. – 1480-1486. DOI: 10.1373/clinchem.2004.047399.
13. Seasonal and socioeconomic influences on thyroid function among the Yakut (Sakha) of Eastern Siberia / S.B. Levy, W.R. Leonard, L.A. Tarskaia [et al.] // Am J Hum Biol. – 2013. – V. 25. – P. 814–820. DOI: 10.1002/ajhb.22457.
14. Seasonal variation in hormonal concentrations in Australian Antarctic personnel / R. Vining, R. McGinley, L. Holliday [et al.] // Endocrine Society of Australia Proceedings. – 1983. – V. 26. – P. 79.
15. Semi-annual seasonal pattern of serum thyrotropin in adults / D. Santi, G. Spaggiari, G. Brigante [et al.] // Sci Rep. – 2019. – V. 9(1). – P. 10786. DOI: 10.1038/s41598-019-47349-4
16. The pituitary-thyroid axis in healthy men living under subarctic climatological conditions / J. Hassi, K. Sikkilä, A. Ruokonen [et al.] // J Endocrinol. – 2001. – V. 169. – № 1. – P. 195-203. DOI: 10.1677/joe.0.1690195.
Review
For citations:
Molodovskaya I.N., Tipisova E.V., Popkova V.A., Elfimova A.E., Potutkin D.S. Photoperiodic variation of thyroid hormones and autoantibodies in males of the European North. Yakut Medical Journal. 2020;(2):77-80. https://doi.org/10.25789/YMJ.2020.70.23
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