Microbiological characteristics of Streptococcus pneumoniae strains isolated in Yakutsk
https://doi.org/10.25789/YMJ.2020.70.14
Abstract
The microbiological and molecular genetic characteristics of S. pneumoniae strains, identified during nasopharyngeal carriage, were determined in patients from the age of 6 months up to 85 years old, living in Yakutsk.
The obtained data indicate the prevalence of virulent antibiotic-resistant S. pneumoniae strains among the population of Yakutsk and dictate the need for further epidemiological and microbio-logical studies of this problem.
About the Authors
Ya. A. AkhremenkoRussian Federation
Akhremenko Yana Aleksandrovna – Candidate of Medical Sciences, Docent, Associate Professor of the Department of Histology and Microbiology of Medical Institute
A. E. Goncharov
Russian Federation
Goncharov Artemiy Evgenyevitch – doctor of medical sciences, professor at the Department of Epidemiology, Parasitology and Disinfectology
191015, Saint-Petersburg, Kirochnaya St, 41, 8 (812) 303-50-00;
head of Laboratory for Functional Genomic and Proteomic of Microorganisms of Department of Molecular Microbiology
197376, Saint-Petersburg, Academica Pavlova St, 12, 8 (812) 234-68-68
V. V. Kolodzhieva
Russian Federation
Kolodzhieva Viktoriya Vasilievna – candidate of medical Sciences , associate Professor of the Department of epidemiology, Parasitology and Disinfectology
191015, Saint-Petersburg, Kirochnaya St, 41, 8 (812) 303-50-00
E. Yu. Belonogova
Russian Federation
Belonogova Ekaterina Yurievna – PhD student at the Department of Molecular Microbiology
197376, Saint-Petersburg, Academica Pavlova St, 12, 8 (812) 234-68-68
D. S. Kolesnik
Russian Federation
Kolesnik Dmitriy Sergeevitch – PhD student at the Department of Epidemiology, Parasitology and Disinfectology
191015, Saint-Petersburg, Kirochnaya St, 41, 8 (812) 303-50-00
A. S. Mochov
Russian Federation
Mochov Aleksey Sergeevitch – PhD student at the Department of Epidemiology, Parasitology and Disinfectology
191015, Saint-Petersburg, Kirochnaya St, 41, 8 (812) 303-50-00
V. I. Ilarova
Russian Federation
Ilarova Vera Innokentievna – head of the Educational and scientific microbiological laboratory of the Clinic
L. A. Tarasova
Russian Federation
Tarasova Lidia Andreevna - Candidate of Medical Sciences, Docent, Associate Professor of the Department of Histology and Microbiology of Medical Institute
References
1. Kozlov R.S. Pneumococci: past, present and future / R.S. Kozlov. - Smolensk: Smolensk state medical Academy, 2005. - 128 p.
2. Pneumococcal infection and modern possibilities of its prevention — an epidemiological review of the situation in the world and in Russia / S.V. Sidorenko, Yu.V. Lobzin, S.M. Harit [et al.] // Issues of modern Pediatrics. – 2010. – V. 9, №1. – Р. 62-69.
3. Rainert R.R. New data on the effectiveness of 13-valent pneumococcal conjugate vaccine against invasive pneumococcal infections, pneumonia, acute otitis media and nasopharyngeal carrier / R.R. Rainert, B. Tajshi // Pediatric pharmacology. – 2012. - №3. – Р. 8-11.
4. Serotype diversity and resistance of pneumococci / N.A. Mayansky, N.M. Alyabyeva, A.V. Lazareva, L.K. Katosova // Annals of the Russian Academy of Medical Sciences. 2014. - № 7–8: 38–45.
5. A variable region within the genome of Streptococcus pneumoniae contributes to strainstrain variation in virulence / R.M. Harvey, U.H. Stroeher, A.D. Ogunniyi [et al.] // PLoS One. 2011. 6(5). DOI: 10.1371/journal.pone.0019650
6. Cornick J.E. Streptococcus pneumoniae: the evolution of antimicrobial resistance to beta-lactams, fluoroquinolones and macrolides / J.E. Cornick, S.D. Bentley // Microb. Infect. 2012; 14: 573–583. DOI: 10.1016 / j.micinf.2012.01.012.
7. Detection of erythromycin-resistant determinants by PCR / J. Sutcliffe, T. Grebe, A. Tait-Kamradt, L. Wondrack // Antimicrob Agents Chemother 1996;40:2562-6.
8. Molecular epidemiology of erythromycin resistance in Streptococcus pneumoniae isolates from blood and noninvasive sites / M.R. Amezaga, P.E. Carter, P. Cash, H. McKenzie//J. Clin. Microbiol. 2002. 40:3313-3318. DOI: 10.1128/JCM.40.9.3313–3318.2002
9. Rarely occurring 19A-like cps locus from a serotype 19F pneumococcal isolate indicates continued need of serology-based quality control for PCR-based serotype determinations / F.C. Pimenta, REJr Gertz, A. Yu J. Roundtree // J. Clin Microbiol. 2009 Jul;47(7):2353-4. DOI: 10.1128/JCM.00704-09.
10. Reinert R.R. The antimicrobial resistance profile of Streptococcus pneumoniae / R.R. Reinert // Clin. Microbiol. Infect. 2009; 15 (Suppl. 3): 7–11. DOI: 10.1111/j.1469-0691.2009.02724.x.
11. Retsema J. Macrolides: structures and microbial targets / J. Retsema, W. Fu // Int. J. of Antimicrob. Agents. 2001; 3–10.
12. Clinical validation of multiplex real-time PCR assays for detection of bacterial meningitis pathogens / X. Wang [et al.] // J. Clin. Microbiol. 50, 702–708 (2012)
13. Zapun C. Penicillin-binding proteins and beta-lactam resistance / C. Zapun, T.V. Contreras-Martel // FEMS Microbiol. Rev. 2008; 32: 361–385. DOI: 10.1111/j.1574-6976.2007.00095.x.
Review
For citations:
Akhremenko Ya.A., Goncharov A.E., Kolodzhieva V.V., Belonogova E.Yu., Kolesnik D.S., Mochov A.S., Ilarova V.I., Tarasova L.A. Microbiological characteristics of Streptococcus pneumoniae strains isolated in Yakutsk. Yakut Medical Journal. 2020;(2):47-49. https://doi.org/10.25789/YMJ.2020.70.14