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Liquid cytology in comparison with traditional in the diagnosis of cervical diseases

https://doi.org/10.25789/YMJ.2020.70.05

Abstract

This paper presents the results of a cytological study of patients with pathology of the cervix uteri (CU) based on traditional cytology (TC) and on liquid-based cytology (LBC). It was found that the combined use of liquid-based cytology and conventional cytology can improve the effectiveness of CU pathology diagnostics. It is recommended to complete the cytological study with testing for human papillomavirus (HPV). The use of these screening methods (cytological and HPV tests) contribute to improving the early diagnosis, monitoring, and prognosis of CU cancer.

About the Authors

M. P. Kirillina
Yakut Science Centre of Complex Medical Problems Laboratory; NEFU Medical Institute Clinic Laboratory
Russian Federation

Kirillina Maria Petrovna – Candidate of Biological Sciences, Senior Research Scientist, Head;

Head

89142716881



S. I. Sofronova
Yakut Science Centre of Complex Medical Problems Laborator
Russian Federation

Sofronova Sargylana Ivanovna – Candidate of Medicine, Senior Research Associate, Head of Scientific and Organizational Department

89841094825



I. V. Kononova
Yakut Science Centre of Complex Medical Problems Laboratory
Russian Federation

Kononova Irina Vasilievna – Candidate of Medical Science, Research Worker

89243683673



A. K. Ivanova
diagnostic center "National hospital №1- National medical center"; NEFU Medical Institute Clinic
Russian Federation

Ivanova Anna Konstantinovna – Сlinical pathologist (cytology);

Clinical Pathologist

89248647588



V. A. Vorontsova
ООО «МАЛЕКС»
Russian Federation


E. L. Lushnikova
FSBIS Institute of Molecular Pathology and Pathomorphology “Federal Research Center of Fundamental and Translational Medicine”
Russian Federation

Lushnikova Elena Leonidovna – Doctor of Biological Science, professor, the head

630117,Novosibirsk,Timakova st.,2

8(383)334-80-03



References

1. Bovykina G.A. Cytological study - early diagnosis of cervical cancer / G.A. Bovykina // Laboratory diagnosis. - №4 (134). - 2015. – p. 35-37. https://cyberleninka.ru/article/n/tsitologicheskoe-issledovanierannyaya-diagnostika-raka-sheyki-matki/viewer

2. Malignant neoplasms in Russia in 2007 (morbidity and mortality) / Ed. I.V. Chissov, V.V. Starinsky, G.V. Petrova. M.: FGU «P.A. Herzen Russian Technologies MNII”, 2009. - 244 p.

3. Clinical and morphological aspects of cervical papillomavirus infection / L.A. Kolomiets, L.N. Urazova, N.V. Sevastyanova [et al.] // Oncology Issues. - 2002. -V. 48, №1. - P.43–46.

4. Kasoyan K.T. The method of liquid cytology in the diagnosis of cervical diseases: a training manual / K.T.Kasoyan, T.V.Dzhangirova // M.: RMAPO. – 2012. – 23p. http://irbis.rmapo.ru/UploadsFilesForIrbis/f303d0ae387de4afa8b027efec7db8ed.pdf

5. Kazaishvili T.N. Early diagnosis of cervical cancer by liquid cytology. Research and practice in medicine. National Congress “Oncology of reproductive organs from prevention and early detection to effective treatment” / T.N.Kazaishvili. - M.: KVAZAR, 2016. – p.80-81. https://cyberleninka.ru/article/v/rannyaya-diagnostika-raka-sheyki-matki-metodom-zhidkostnoy-tsitologii-1

6. Kogan E.A. Monitoring of patients who underwent cervical conization for cervical intraepithelial neoplasia (clinical, morphological and molecular biological aspects of the problem) / E.A. Kogan, N.M. Fayzullina, A.Kh. Israilova // Obstetrics and gynecology. - 2012. - №1. – p.70-74. https://aig-journal.ru/articles/Monitoring-bolnyh-perenesshih-operaciu-konizacii-sheiki-matki-po-povodu-cervikalnoi-intraepitelialnoi-neoplazii-kliniko-morfologicheskie-i-molekulyarn.html

7. Prilepskaya V.N. Diseases of the cervix, vagina and vulva / B.N. Prilepskaya. -M. -MED pre-inform, 2005. - P.432.

8. The role of virological factors in the development of cervical cancer in young women / L.A. Evstigneeva, E.V. Bakhidze, V.V. Semiglazov [et al.] // Journal of Obstetrics and Women's Diseases. - 2007. - V. LVII. - p.153-154. http://www.oncology.tomsk.ru/nii/journal/2012/3/files/soj_2012_3_34-40.pdf

9. Baseline cytology, human papillomavirus testing, and risk for cervical neoplasia: a 10-year cohort analysis / M.E.Sherman, A.T.Lorincz, D.R.Scott [et al.] // J. Natl. Cancer Inst. - 2003. - Vol. 95. -P.46–52.

10. Cumulative 5-year diagnoses of CIN2, CIN3 or cervical cancer after concurrent high-risk HPV and cytology testing in a primary screening setting / H.Hoyer, C.Scheungraber, R. KuehneHeid [et al.] // Int.J. Cancer. - 2005. - Vol. 116. - P. 136–143.

11. Chapter 9: Clinical applications of HPV testing: a summary of meta-analyses / M.Arbyn, P.Sasieni, C.Meijer [et al.] // Vaccine. - 2006. - Vol. 24. - Suppl. 3. - p.78–89.

12. Efficacy of human papillomavirus testing for the detection of invasive cervical cancers and cervical intraepithelial neoplasia: a randomized controlled trial /G.Ronco, P.Giorgi-Rossi, F. Carozzi [et al.] // Lancet Oncol. – 2010. – Vol. 11, № 3. – P. 249–257. https://www.ncbi.nlm.nih.gov/ pubmed/20089449

13. Inclusion of HPV testing in routine cervical cancer screening for women above 29 years in Germany: results for 8466 patients / K.U.Petry, S. Menton, M.Menton [et al.] // Br. J. Cancer. - 2003. - Vol. 88. - P. 1570–1577.

14. Rate of cervical cancer, severe intraepithelial neoplasia, and adenocarcinoma in situ in primary HPV DNA screening with cytology triage :randomised study within organised screening programme/ A.Anttila, L.Kotaniemi-Talonen, M. Leinonen [et al.] // BMJ. – 2010. – Vol. 340. – P. 1804. https://www.bmj.com/content/340/bmj.c1804

15. Type – specific human papillomavirus DNA in abnormal smears as a predictor of high – grade cervical intraepithelial neoplasia / J.Cuzick, G.Terry, L.Ho [et al.] // Br. J. Cancer. 1994. - Vol. 69. - P.167–171.

16. The Bethesda System for Reporting Cervical Cytology: Definitions, criteria, and explanatory notes. / Springer. 3rd Edition. Nayar, Ritu; Wilbur, David C. (Eds), 2015.– p.321. https://link.springer.com/content/pdf/10.1007%2F978-3-319-11074-5.pdf


Review

For citations:


Kirillina M.P., Sofronova S.I., Kononova I.V., Ivanova A.K., Vorontsova V.A., Lushnikova E.L. Liquid cytology in comparison with traditional in the diagnosis of cervical diseases. Yakut Medical Journal. 2020;(2):18-20. https://doi.org/10.25789/YMJ.2020.70.05

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ISSN 1813-1905 (Print)
ISSN 2312-1017 (Online)