Signaling functions of fatty acids in the placenta
https://doi.org/10.25789/YMJ.2021.73.25
Abstract
This review summarizes the current understanding of FA-activated signal transduction systems in the placenta in the data PubMed, Google Scholar. Their effect on membrane and nuclear receptors, as well as their participation in the processes of decidualization and modulation of inflammation in the placenta, associated with G-protein-coupled receptors, have been shown. The effects of peroxisome proliferator-activated receptors mediated FAs in the placenta are described. Particular attention is paid to the Toll-mediated inflammatory signaling pathways of the FAs in the placenta. Research data on the effect of FAs on the expression of genes involved in placenta angiogenesis are summarized.
About the Authors
N. A. Ishutina
Far Eastern Scientific Center of Physiology and Pathology of Respiration
Russian Federation
Russian Federation
Ishutina Nataliа A. – PhD, D.Sc. (Biol.), Leading Staff Scientist of Laboratory of Mechanisms of Etiopathogenesis and Recovery Processes of the Respiratory System at NonSpecific Lung Diseases
22 Kalinina Str., Blagoveshchensk, 675000
I. A. Andrievskaya
Far Eastern Scientific Center of Physiology and Pathology of Respiration
Russian Federation
Russian Federation
Andrievskaya Irina A. – PhD, D.Sc. (Biol.), Professor RANS, Head of Laboratory of Mechanisms of Etiopathogenesis and Recovery Processes of the Respiratory System at Non-Specific Lung Diseases
22 Kalinina Str., Blagoveshchensk, 675000
M. N. German
Far Eastern Scientific Center of Physiology and Pathology of Respiration
Russian Federation
Russian Federation
German Marina N. – Research Assistant at the Laboratory of Mechanisms of Etiopathogenesis and Recovery Processes of the Respiratory System at Non-Specific Lung Diseases
22 Kalinina Str., Blagoveshchensk, 675000
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Review
For citations:
Ishutina N.A., Andrievskaya I.A., German M.N. Signaling functions of fatty acids in the placenta. Yakut Medical Journal. 2021;(1):92-97. https://doi.org/10.25789/YMJ.2021.73.25
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