The relationship of parameters of the pituitary-gonadal axis and dopamine with meteorological factors in healthy men living in the Subarctic
https://doi.org/10.25789/YMJ.2023.83.23
Abstract
Aim: to evaluate the influence of circannual dynamics of meteorological factors of the temperate continental climate on the levels of sex hormones and dopamine as well as antisperm antibodies in men living in subarctic environmental conditions.
Materials and methods. The concentrations of follicle stimulating hormone, luteinizing hormone, prolactin, progesterone, dopamine, cortisol, total and free testosterone, estradiol, sex hormone-binding globulin, dehydroepiandrosterone sulphate, antisperm antibodies were determined in the blood by the enzyme immunoassay on a quarterly basis (December, March, June, September) for one year in 20 healthy men of Arkhangelsk. The relationships between the hormonal data and the climatic data were assessed by using the Spearman correlation coefficient.
Results. Seasonal fluctuations in the levels of estradiol and antisperm antibodies are comparable to changes in the daylight hours, fluctuations in atmospheric pressure, temperature and relative humidity. Seasonal changes in luteinizing hormone levels are associated with the fluctuations in atmospheric air pressure. Daylight affect annual dopamine dynamics, which also correlated with atmospheric pressure and relative air humidity. Total and free testosterone levels in men are relatively constant throughout the year and do not appear to be influenced by the weather factors.
Conclusion. An increase in day length and air temperature is associated with an increase in estradiol and dopamine levels and a decrease in antisperm antibodies values. We believe that the seasonality of estradiol and antisperm antibodies is a daylight effect mediated by changes in the melatonin levels, just as dopamine seasonality is mediated by changes in vitamin D levels.
About the Authors
I. N. Molodovskaya
N. Laverov Federal Center for Integrated Arctic Research
Russian Federation
Russian Federation
MOLODOVSKAYA Irina Nikolaevna – PhD in Biology, senior researcher
E. V. Tipisova
N. Laverov Federal Center for Integrated Arctic Research
Russian Federation
Russian Federation
TIPISOVA Elena Vasilievna – Doctor of Biology, chief researcher
A. E. Elfimova
N. Laverov Federal Center for Integrated Arctic Research
Russian Federation
Russian Federation
ELFIMOVA Alexandra Eduardovna – PhD in Biology, senior researcher
V. A. Alikina
N. Laverov Federal Center for Integrated Arctic Research
Russian Federation
Russian Federation
ALIKINA Victoria Anatolievna – PhD in Biology, senior researcher
V. N. Zyabisheva
N. Laverov Federal Center for Integrated Arctic Research
Russian Federation
Russian Federation
ZYABISHEVA Valentina Nikolaevna – junior researcher
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Review
For citations:
Molodovskaya I.N., Tipisova E.V., Elfimova A.E., Alikina V.A., Zyabisheva V.N. The relationship of parameters of the pituitary-gonadal axis and dopamine with meteorological factors in healthy men living in the Subarctic. Yakut Medical Journal. 2023;(3):93-97. https://doi.org/10.25789/YMJ.2023.83.23
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