The role of blood transport proteins in adaptation reactions to extremely uncomfortable conditions of the North and the Arctic
https://doi.org/10.25789/YMJ.2024.86.18
Abstract
The purpose of this review is to integrate data on the role of blood transport proteins in adaptation reactions to extremely uncomforTable conditions of the North and Arctic of the Russian Federation. Regulation of shifts in homeostasis in humans under unfavorable Arctic conditions is carried out, among other things, by increasing the production of haptoglobin and transferrin, which perform antioxidant and immunomodulatory functions. An increase in the concentration of immunoglobulins in the blood ensures the efficiency of utilization of metabolic products, components of cellular destruction and damage. In the unfavorable conditions of the North and the Arctic, a shift and disruption of adaptive changes in lipid metabolism occurs.
About the Authors
K. O. Pashinskaya
Institute of physiology of natural adaptations at the N. Laverov Federal Center for Integrated Arctic Research of the Ural Branch of the Russian Academy of Sciences
Россия
Россия
Pashinskaya Ksenia Olegovna – junior researcher at the laboratory regulatory mechanisms of immunity
A. V. Samodova
Institute of physiology of natural adaptations at the N. Laverov Federal Center for Integrated Arctic Research of the Ural Branch of the Russian Academy of Sciences
Россия
Россия
Samodova Anna Vasilievna – PhD (Biology), Leading Researcher, Head of laboratory regulatory mechanisms of immunity
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Review
For citations:
Pashinskaya K.O., Samodova A.V. The role of blood transport proteins in adaptation reactions to extremely uncomfortable conditions of the North and the Arctic. Yakut Medical Journal. 2024;(2):75-80. https://doi.org/10.25789/YMJ.2024.86.18
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