Parameters for assessing the state of cerebral energy exchange of elderly women living in the arctic zone of the Russian Federation

Neuroenergy exchange of the brain acts as a significant indicator affecting the preservation of neuropsychic activity in elderly age The aim of the study was to identify the features of the DC-potential level in various periods of old age in women living in the Arctic zone of the Russian Federation. The study involved 192 Northerners who were divided into age groups: 1 — 60-64 YO; 2 — 65-69 YO; 3 — 70-74 YO. The evaluation of cerebral energy exchange indicators was carried out by the hardware and software diagnostic complex "Neuroenergometer-KM" "Statokin". Registration of the DC-potential level was carried out monopolarly from 12 leads esTableished in accordance with the international scheme 10-20.

In the studied groups of elderly women, there is a change in the median values of the DC-potential level, demonstrating pronounced fluctuations in the distribution of brain energy consumption in the aging process. Brain metabolism decreases with age, but in old age there may be a multidirectional change between glucose metabolism and acid-base balance, indicating oxidative stress.

Then, at the age of 65-69, there is a gradual development of mental and physiological compensatory mechanisms, which leads to a relative normalization of neuroenergy exchange of the brain. The next increase in the DC-potential level of the brain begins to be traced at the age of 70-74 years. Probably, it is at this age that the decline of physiological compensatory processes begins to occur.

The obtained results made it possible to identify the peculiarities of the distribution of the DC-potential level in women of different age groups and to esTableish normative values. The developed standards will improve the quality of diagnostics of the functional state of the brain in women living in the Arctic Zone of the Russian Federation, and will also allow timely monitoring brain functional changes in aging.

1. Klimenko L.L., Deev A.I., Fokin V.F. Brain energy metabolism in gerontological aspect // Clinical gerontology. 2010. No. 9-10. P. 37-38

2. Kotsova O.N., Anikina N.Yu., Gribanov A.V. Sexual differences of cerebral energy exchange in residents of the Arctic zone of the Russian Federation // Bulletin of the Ural Medical Academic Science. 2021. Vol.18. No. 1. P. 4-12

3. Maksimova A.A., Silina Yu.M. Diagnostic possibilities of neuroenergic mapping in hypoxic brain lesions // International Scientific Research Journal. 2021. No. 1. (103) Part 3. P. 46-51.

4. Neuroenergomapping: a new diagnostic tool for pathophysiological changes in the central nervous system in children with developmental disorders / A.A. Maksimova [et al.]. // Universum: medicine and pharmacology: electron. scientific. journal. "Medicine and pharmacology". 2021. 1(74). URL: https://7universum.com/ru/med/archive/item/11142].

5. Features of adaptation of brain metabolism and the formation of diseases of the nervous system / L.P. Sokolova, [et al.]. // Eurasian Union of Scientists. 2016. No.29-1. P. 65-68.

6. The reaction of cerebral energy metabolism to cold stress in young people living in the Arctic region of the Russian Federation / A.V. Gribanov, N.Yu. Anikina, I.S. Kozhevnikova [et al.]. // Human Ecology. 2019. No.3. P. 17-23

7. Romanchuk N. P. Human brain and nature: modern regulators of cognitive health and longevity // Bulletin of Science and practice. 2021. No. 6. P. 146-190

8. Super-slow physiological processes of the human and animal brain in experimental and clinical studies / Galimov N. M. [et al.]. // Medical Bulletin of Bashkortostan. 2009. No.3. P. 63-69

9. Sibil V.I. Age dynamics of brain activity // Bulletin of Experimental Education. 2017. №4 (13). P. 628-630

10. Sokolova L.P., Chernyaev S.A. Neurofunctional brain activity: age aspect // Therapy. 2020. No. 6 (3). P. 15-20

11. Aging of the human brain: morphofunctional aspects / A.V. Gribanov [et al.]. // Journal of Neurology and Psychiatry named after S.S. Korsakov. Special issues. 2017. Vol.117 (1-2). P. 3-7.

12. Stresses, comorbidity and quality of life of an elderly patient / E.S. Akarachkova [et al.]. // Difficult patient. 2019. No.10. P.19-27

13. Fokin V. F., Ponomareva N. V. Energetic physiology of the brain. M.: Antidor, – 2003. 288 p.

14. Functional brain activity in elderly women of the Arctic Zone of the Russian Federation with different vegetative tone / A.V. Gribanov [et al.]. // Human Ecology. 2023. No. 3. P. 231-240

15. Functional state of the brain in elderly women with varying degrees of anxiety / I.L. Fateeva [et al.]. // Clinical gerontology. 2022. Vol. 28. No. 7-8. P. 55-60

16. Characteristics of cerebral energy metabolism in elderly people with impaired cognitive functions / N.A. Lisova, E.A. Chereneva, S.N. Shilov, N.V. Nikiforova //siberian Journal of Life Sciences and Agriculture. 2022. No. 5. P. 246-261

17. Shmyrev V.I., Sokolova L.P., Knyazeva I.V., Adaptive reactivity of brain metabolism as a universal pathogenetic factor of disease development and rehabilitation capabilities of the body. // Kremlin medicine. Clinical Bulletin. 2013. No.3. P. 53-56.