The features of a morphological picture and the immune status of patients depending on clinical current of ulcer of stomach and duodenum
Abstract
Purpose. Studying insemination, morphological pictures and conditions of local immune reaction of mucous membrane of stomach and duodenum in patients with various degree of severity of current of ulcer of stomach.
Materials and methods. Inspection of 100 workers of «Yakutugol’” company, suffering from ulcer of stomach and (or) duodenum, was carried out. They underwent endoscopy examination with target biopsy and detection Нр in biopsy material. Insemination Нр was defined before carrying out of treatment, control examination was carried out in 1 month after antichelicobacterial therapy.
Results. Severe treatment of ulcer of stomach was accompanied by the development of relapses (12.0 %), increase of levels IL-4 and α-PNO in 2 times and more expressed character of changes of mucous membrane. Full eradication was more often in patients with mild and an average degree of current of ulcer of stomach (78.0 %).
Conclusion. Detection of level of IL-4 and α-PNO is an accessible and effective method of detecting the condition of local immune reaction of mucous membrane of stomach and duodenum.
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Review
For citations:
Kurbatova T.N. The features of a morphological picture and the immune status of patients depending on clinical current of ulcer of stomach and duodenum. Yakut Medical Journal. 2007;(1):24-26. (In Russ.)
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