Identification of chromosomal breakpoints in men with structural chromosome rearrangement and reproductive failure
Abstract
In tHis study we introduce the results of molecular-cytogenetic study of five men with chromosome rearrangements and reproductive failure. They are patients of the Center for Reproductive Medicine in Krasnoyarsk. Using SKY technique in four cases and FISH method in three cases we localized chromosome breakpoints and found unbalanced translocations in three patients and balanced translocations in two patients.
About the Authors
N. V. Zotova
Красноярский Центр репродуктивной медицины
Russian Federation
Russian Federation
E. V. Markova
Красноярский Центр репродуктивной медицины
Russian Federation
Russian Federation
I. J. Timofeeva
Красноярский Центр репродуктивной медицины
Russian Federation
Russian Federation
O. M. Kazantseva
Красноярский Центр репродуктивной медицины
Russian Federation
Russian Federation
N. V. Kazmina
Красноярский Центр репродуктивной медицины
Russian Federation
Russian Federation
A. V. Svetlakov
Красноярский Центр репродуктивной медицины
Russian Federation
Russian Federation
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Review
For citations:
Zotova N.V., Markova E.V., Timofeeva I.J., Kazantseva O.M., Kazmina N.V., Svetlakov A.V. Identification of chromosomal breakpoints in men with structural chromosome rearrangement and reproductive failure. Yakut Medical Journal. 2009;(2):75-78. (In Russ.)
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