Chemotherapy of colorectal cancer
Abstract
A comparative analysis of efficacy and toxicity of standard chemotherapy scheme irinotecan +fluorouracil + leucovorin in patients with colon cancer in the Blochin’s Oncological Centre and chemotherapy department of Oncologic dispensary was held. Particular attention was paid to tolerability and toxicity of the given chemotherapy scheme. The findings suggest that the standard chemotherapy regimen irinotecan +fluorouracil + leucovorin is an effective and well tolerated treatment for colon cancer.
About the Authors
F. G. Ivanova
ЯНЦ КМП СО РАМН;
ЯРОД
Russian Federation
Russian Federation
P. M. Ivanov
ЯНЦ КМП СО РАМН;
МИ СВФУ им. М.К. Аммосова
Russian Federation
Russian Federation
T. N. Zharnikova
ЯНЦ КМП СО РАМН;
ГУ ЯРОД
Russian Federation
Russian Federation
V. A. Gorbunova
ЯНЦ КМП СО РАМН;
РОНЦ им. Н.Н. Блохина РАМН
Russian Federation
Russian Federation
References
1. Garin A.M. Ten the most extensive tumors /A.M. Garin, I.S. Bazin-M.: Agency “CreativeManagement-Consulting”, 2006.
2. Gorbunova V.A. Adjuvant chemotherapy of colorectal cancer /V.A. Gorbunova. Remedium .- 2006 .- Spec.ed. № 2. - P. 2-7.
3. Ivanov P.M. Malignant neoplasms in Yakutia in the turn of the century /P.M. Ivanov, M.I. Tomskiy, P.D. Karataev / Yakutsk, 2008.- 268 p.
4. Perevodchikova N.I. Guidelines for chemotherapy of tumor diseases /N.I. Perevodchikova. - M., 2005. – 230 p.
5. Reutova E.V. Chemotherapy of disseminated forms of colon cancer: autoref. diss. ... cand. med. sciences /E.V. Reutova. – M., 2002.
6. Superiority of oxaliplatin and fluorouracilleucovorin compared with either therapy alone in patient with progressive colorectal cancer after irinotecan and fluorouracil-leucovorin: interim results of a phase III trial / M.L. Rothenberg [et al.] // J Clin Oncol 2003; 21:2059-2069.
7. Weekly 24h infusion of high-dose (HD) 5 fluorouracil (5FU 24h) with or without folinic acid (FA) vs bolus 5FU/FA (NCCTG/Mayo) in advanced colorectal cancer (CRC): A randomized phase III staidy of the EORTC GITC- CG and the AIO / H. J. Schmoll [et al.] // Proc. ASCO. – 2000. 19, 241a, abstr. 935
Review
For citations:
Ivanova F.G., Ivanov P.M., Zharnikova T.N., Gorbunova V.A. Chemotherapy of colorectal cancer. Yakut Medical Journal. 2010;(4):47-48.
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