Features of oxidative status of adolescents with undifferentiated connective tissue dysplasia of various severity level
Abstract
Total number of 225 adolescents with clinical features of non-differentiated connective tissue dysplasia (NDCTD) at the different stages and 60 healthy adolescents were examined. The hemiluminiscent method was used for the estimation of biogenesis of free radicals in blood serum. In the group of NDCTD patients the indexes, reflecting the processes of free radical lipid oxidation reliably increased and antioxidant defense system activity decreased. Gender and age related differences in the processes of free radical oxidation were revealed in minimal and severe stages of NDCTD.
About the Authors
R. V. Uchakina
Mother and child institute at SB RAMS
Russian Federation
Russian Federation
680022, Khabarovsk, ul.Voronezghskaya, 49, bldg.1.(Tel.:8(4212) 980-591
O. A. Lebedko
Mother and child institute at SB RAMS
Russian Federation
Russian Federation
680022, Khabarovsk, ul.Voronezghskaya, 49, bldg.1.(Tel.:8(4212) 980-591
O. A. Genova
Far-Eastern state medical university
Russian Federation
Russian Federation
Khabarovsk, ul.M.Amurskogo, 35. (Tel/Fax:8(4212)326-393
E. V. Rakitskaja
Far-Eastern state medical university
Russian Federation
Russian Federation
Khabarovsk, ul.M.Amurskogo, 35. (Tel/Fax:8(4212)326-393
V. K. Kozlov
НИИ охраны материнства и детства СО РАМН
Russian Federation
Russian Federation
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Review
For citations:
Uchakina R.V., Lebedko O.A., Genova O.A., Rakitskaja E.V., Kozlov V.K. Features of oxidative status of adolescents with undifferentiated connective tissue dysplasia of various severity level. Yakut Medical Journal. 2010;(4):25-27.
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