Instrumental reflex of active avoiding on a background of introduction of physiologically active connection
Abstract
Modulating influence of physiologically active connection (Reamberin) on GABA-ergic system of laboratory rats is investigated. Positive changes in behaviour of experimental animals on a background of Reamberin application in a doze of 60 mg/kg intraperitoneally are revealed. Stress protective effect is noted.
About the Authors
M. L. PlastininRussian Federation
T. A. Batalova
Russian Federation
A. A. Sergievich
Russian Federation
References
1. Babenko O.V. GABA-ergic neuromediator system and physiologically active substances breaking its functioning /O.V. Babenko, V.D. Gladkih, V.V. Kiryanov.- M., 2004. - 101 p.
2. Iljuchenok R.J. Pharmacology of behaviour and memory / R.J. Iljuchenok. - Novosibirsk:Science, 1972. - 222 p.
3. Correction of complex behavioural reactions in white he-rats by means of antioxidant application / V.V. Vertinsky [et.al.] // Far East med. J. - 2006. - №4. -p. 90 - 93.
4. Kovalev G.V. Nootropic drugs / G.V. Kovalev. – Nizh.Volzh.publ.house, 1990. - 368 p.
5. Meerson F.Z. Adaptation, stress and prophylaxis / F.Z. Meerson. - М.: Medicine, 1981. - 278 p.
6. Melkonjan M.M. Influence of alpha – tocopherilacetate on some biochemical parameters of blood of white rats in conditions of acoustic stress / M.M. Melkonjan, V.G. Mhitarjan // Bullet. Exper. biol. and med. - 1985. - V. 100, 9. - P.270 - 275.
7. From neuron to brain / J. Nickols [et.al.] - М.: Editorial URSS, 2003. - 672 p.
8. Raevsky K.S. Mediator amino acids: neurophysiologic and neurochemical aspects / K.S. Raevsky, V.P.Georgiev. - M., Medicine, 1996.- 239 p.
9. Manual on experimental (before clinical) studying of new pharmacological substances / under red. R.U. Habriev. - М.: Medicine, 2005. – 832 p.
10. Typological features of behaviour of rats. / N.R. Grigoriev [et al.] // Russ. physiol. J. after I.M. Setchenov. - 2007. V. 93, №8. - P. 817-826.
11. Toxicology of GABA-litics / A.I. Golovko [et al.] - Spb.: Niva, 1996. - 144 p.
12. Shujkin N.N. Behaviour of rats in the darklight chamber: a problem of a place choice / N.N. Shujkin, P.P. Levshina, E.V. Liperovskaja // J. high nerve active. - 2003. - V. 53, № 6. - P. 746-753.
Review
For citations:
Plastinin M.L., Batalova T.A., Sergievich A.A. Instrumental reflex of active avoiding on a background of introduction of physiologically active connection. Yakut Medical Journal. 2010;(3):49-51. (In Russ.)









