Immunopathological disorders in patients with chronic rhinosinusitis, interfacing with Chlamydia infection
Abstract
We show comparative analysis of clinical laboratory study patients with chronic rhinitis and maxillary sinusitis, associated and non-associated with Chlamydia infection. In patients with Chlamydia infection we found one-direction pathological disturbances from the side of immune system, typical for the patients with or without Chlamydia. The disturbances were combined with some peculiarities of immune response to infection agent. In nose and nasal sinus Chlamydia infection disease we didn’t mark the activation of immunity humoral link, found in non-verified Chlamydia infection. Metabolic response of lymphocytes in identified Chlamydia infection was poorly expressed.
About the Authors
T. A. Kapustina
НИИ МПС СО РАМН
Russian Federation
Russian Federation
A. A. Savchenko
НИИ МПС СО РАМН
Russian Federation
Russian Federation
O. V. Parilova
НИИ МПС СО РАМН
Russian Federation
Russian Federation
O. A. Kolenchukova
НИИ МПС СО РАМН
Russian Federation
Russian Federation
T. I. Kin
НИИ МПС СО РАМН
Russian Federation
Russian Federation
E. V. Lopatnikova
НИИ МПС СО РАМН
Russian Federation
Russian Federation
References
1. Berezov T.T. Biological chemistry / T.T. Berezov, B.F. Korovkin - М.: Medicine, 1998.
2. Granitov V.M. Clamidiosis / V.M. Granitov - М.: “ Medical book “, 2002. - 187 p.
3. Ershov V.I. Clinical value of interaction of Chlamydia infection (Chlamydia pneumonia) and of free-radical processes at ischemic heart disease / V.I. Ershov, A.H. Kogan, I.J. Gadaev //Therapist. arch. - 2001. - 11. - P. 44-48.
4. Value of Chlamydia infection in development of pharynx chronic inflammatory diseases / V.I. Linkov, G.P. Tsurikova, I.V. Nuralova [et.al.] // News of otolaryngology and logopathology: Thes. Rep. XV Congress of otolaryngologists. - SPb., 1995. - V.3. – P. 164.
5. Lobzin J.V. Chlamydia infections / J.V. Lobzin, J.I. Ljashenko, A.L. Poznyak. - Spb.: V., 2003. - 396 p.
6. Poznyak A.L. Generalized forms of the Chlamydia infection with primary lesion of ETNorgans: diagnostics, clinic of treatment prospect/ A.L. Poznyak, L.A. Glaznikov, S.N. Ponidelko // Actual problems of diagnostics and treatment in versatile medical establishment, April, 26-27, 2001: Mater. of the 5th All-Russian scien.pract. conf.- SPb., 2001. -p. 68-69.
7. Savchenko A.A. Bioluminescent definition of NAD- and NADF-dependent glutamatdehydrogenases lymphocytes activity / A.A. Savchenko // Lab.delo-1999.-11. p. 22-25.
8. Soloveva A.M. Status of immune system and efficiency of immunocorrective treatment in patients with chronic persistent Chlamydia infection / A.M. Soloveva // Therapist. arch. - 1996. - №11. - p. 48-51.
9. Tjukavkin V.V. Urogenital clamidiosis: immunobiology, diagnostics, treatment. V.V. Tjukavkin // Bulletin of laboratory service. - 1998; - 7. - P. 10-22.
10. Incidence of Chlamydia trachomatis infections in pregnancy, labor and the newbom / A. Rappai, P. Krasznai, G. Molnar, E. Zavody // Orv. Hetil. - 1995. - Vol. 136. — № 36.- P. 1995-1948.
11. Simple method of circulating immune complex detection in human sera by polyethylene glycol precipitation / V. Haskova, J. Kaslik, J. Riha, J. Rovensky //J. Immunol.-1978.-Vol.154.- Р. 399-406.
12. Ogava H. Recovery of Chlamydia pneumoniae and Chlamydia trachomatis in a patient with recurrent tonsillitis, bronchitis and otitis media with effusion / H. Ogava, K. Hashiguchi, Y. Kazuyama // Kansenshogaku Zasshi. - 1991. - Vol.65, №2. - P. 234-238.
13. Roblin P.M. Microbiologic Efficacy of Azithromycin and Susceptibilities to Azithromycin of Isolates of Chlamydia pneumoniae and Children with Community Acquired Pneumonia / P.M. Roblin, M.R. Hammerschlag // Antimicrobial Agents and Chemotherapy. - 1998. - Vol. 42, № 1. - P. 194-196.
14. Shaw E. Prevalence of and risk factors for Chlamydia in a rural pregnant population / E.Shaw, D.Roberts, P.D.Connor // Fam. Pract. - 1995. - Vol. 41. - N 3. - P. 257-260.
15. Stephens R.S. Chlamydia. Intracellular biology, pathogenesis and immunity / R.S. Stephens. - Washington: ASM Press, 1999. – 384 p.
Review
For citations:
Kapustina T.A., Savchenko A.A., Parilova O.V., Kolenchukova O.A., Kin T.I., Lopatnikova E.V. Immunopathological disorders in patients with chronic rhinosinusitis, interfacing with Chlamydia infection. Yakut Medical Journal. 2010;(3):31-35. (In Russ.)
Views:
29
Email this article 