Clinical case: primary-plural synchronic malignant tumors in mother and breast cancer in daughter
Abstract
One of the effective approaches, promoting early revealing of breast cancer, is DNA-diagnostics of disease hereditary forms which develop in most cases because of presence of mutations in BRCA-1 and BRCA-2 tumor genes-suppressors. Definition of mutations in genes is objective criterion for formation of groups of the increased risk of development of breast and ovarian cancers with the purpose of prevention and duly diagnostics.
About the Authors
L. N. Korosteleva
ИПОВ СВФУ
Russian Federation
Russian Federation
A. D. Makarov
МИ СВФУ им. М.К. Аммосова
Russian Federation
Russian Federation
References
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2. Наследственный рак: идентификация, генетическая гетерогенность, медико-генетическое консультирование / Р.Ф. Гарькавцева [и др.] // Вестник РАМН. – 2001. – № 9. – С. 27-32.
3. Natural history of hereditary cancer of the breast and colon / W. Albano [et al.] Cancer 1982; 50: 360-363.
Review
For citations:
Korosteleva L.N., Makarov A.D. Clinical case: primary-plural synchronic malignant tumors in mother and breast cancer in daughter. Yakut Medical Journal. 2010;(2):105-107. (In Russ.)
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