Indicators of cytokine profile in patients with juvenile idiopathic arthritis
Abstract
The results of immunological study of 58 patients with juvenile idiopathic arthritis are given. It was found out that in all forms of the disease substantial changes of cytokine status in serum and synovial fluid were observed, the degree of severity depends on the variant and the activity of the inflammatory process. Study of cellular immunity was held to a differentiated approach to the choice of therapy, as well as the efficiency of the drugs varied depending on the variant of the disease. The greatest efficiency in the treatment of polyarticular and oligoarticular spreading form was observed in remicade, combination therapy with sandimmun-neoral and methotrexate is preferable to use at oligoarticular persistent form of juvenile idiopathic arthritis.
About the Author
E. N. Tepikina
SEI HPE Samara State Medical University
Russian Federation
Russian Federation
Tepikina Ekaterina - intramural graduate faculty of the Department of Pediatrics
Department of Health and Social Development of Russian Federation Home
443084, Samara, Novo-Vokzalnaya street, 231, 78
Mob. 8-917-119-30-67
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Review
For citations:
Tepikina E.N. Indicators of cytokine profile in patients with juvenile idiopathic arthritis. Yakut Medical Journal. 2011;(3):36-39.
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