Role of disease modifying medications in treatment of children with sclerodermiacircumscripta
Abstract
The authors analyzed the effectiveness of therapy four schemes of basic therapy in 97 children with localized scleroderma. As a result, developed a different approach to the appointment of the basic therapy, taking into account the clinical current of disease.
About the Authors
E. N. AmmosovaRussian Federation
E. N. Sivtseva
Russian Federation
References
1. Grebenyuk VN Localized scleroderma in children / VN Grebenyuk // Russian Medicine Journal.-1998. - № 6.
2. Guseva N.G. Systemic sclerosis: clinical, diagnostic, treatment / NG Guseva // Russian Journal of Skin and Venereal disease.- 2002 .- № 4.-C.5-15.
3. Dovzhansky S. Clinical and immunological parallels with localized systemic sclerosis and / S. Dovzhansky // Russian Journal of Skin and Venereal disease.- 2002 .- № 4.-P.26-29.
4. Pulsed High-Dose Corticosteroids Combined With Low-Dose Methotrexate in Severe Localized 34. Scleroderma / A. Kreuter [et al.] // Arch Dermatol.- 2005 -№7 - C.847- 852.
5. Caur S., Dhar S, Kanwar AJ.Treatment of childhood linear morphea with D-penicillamine / Pediatr Dermatol. – 1993. - Jun;10(2). 201-2.
6. Cronstein BN The mexanism of action of methotrexate // Rheum Dis Clin North Am - 1997-№7- 739-755.
7. Curley RK, Macfarlane AW, Evans S, Woodrow JC The treatment of linear morphoea with D-penicillamine // Clin Exp Dermatol.- 1987-№112(1):56-7.
8. Das S.N., Alam M.R., Islam N., Ramhan M.H.Placebo controlled trial of methotrexate in systemic sclerosis // Mymensingh Med J.- 2005 - №1 - C.71-4.
9. Juvenile localized scleroderma: clinical and epidemiological features in 750 children / F. Zulian [et al.] // Rheumatology- 2006- №5 (45)- С.614–620.
10. Falanga V., Medsger T.A. D- penicillamine the treatment of localized scleroderma // Arch Dermatol.-1990.- №5.-C. 609-612.
11. Treatment of Pediatric Localized Scleroderma with Methotrexate / Pamela G. Fitch [et al.] //The Journal of Rheumatology.- 2006- №3 - 609-14.
Review
For citations:
Ammosova E.N., Sivtseva E.N. Role of disease modifying medications in treatment of children with sclerodermiacircumscripta. Yakut Medical Journal. 2012;(1):10-12.








