Systemic thrombolytic therapy of ischemic stroke. Clinical follow-up according to the Regional Vascular Center (Yakutsk) data
Abstract
Systemic thrombolytic therapy can significantly reduce the degree of neurological deficit and improve outcome in patients with ischemic stroke. The effectiveness of this method was illustrated by the presented clinical report of systemic thrombolysis in ischemic stroke patient in Regional Vascular Centre, Yakutsk. The “dramatic” decrease of focal symptoms (NIHSS score 2 points) occurred after thrombolysis in 44-old-year patient had initial severe neurological deficits (hemiplegia, hypoesthesia, dysarthria, gaze paresis (NIHSS score 15 points)). This led to the full recovery of lost function and to the independence of the patient’s daily life. Thus, systemic thrombolytic therapy can significantly reduce the degree of neurological deficit and improve outcome in patients with ischemic stroke.
About the Authors
S. A. Chugunova
Regional Vascular Center, Republic Hospital №2-Center of Emergency Medicine;
Federal State Institution "Yakut Scientific Center of complex medical problems", Siberian Branch of Russian Academy of Medical Sciences
Russian Federation
Russian Federation
Sargylana Chugunova A.– PhD, Neurologist of Stroke Department
Yakutsk;
Scientific researcher of Department of Epidemiology of chronic non-infectious diseases
83 «A», P. Alekseev street, Yakutsk, 677005, Phone: +7 (4112)43-27-40 Phone: +7 (894)6633455
T. Y. Nikolayeva
North-Eastern federal university named after M.K.Ammosov
Russian Federation
Russian Federation
Tatiana Nikolayeva Y. –MD, professor, Head of Department of Neurology and Psychiatry
36, Kulakovsky street, Yakutsk, 677007, Phone/fax: +7(4112)36-30-46
A. A. Yakovlev
Regional Vascular Center, Republic Hospital №2- Center of Emergency Medicine
Russian Federation
Russian Federation
Alexander Yakovlev A. –Neurologist of Stroke Intensive Care Unit
83 «A», P. Alekseev street, Yakutsk, 677005, Phone: +7 (4112)43-05-34
A. N. Chemezov
Regional Vascular Center, Republic Hospital №2- Center of Emergency Medicine
Russian Federation
Russian Federation
Alexander Chemezov N. –resuscitator physician of Stroke Intensive Care Unit
83 «A», P. Alekseev street, Yakutsk, 677005, Phone: +7 (4112)43-05-34
References
1. Высокая эффективность селективного внутриартериального тромболизиса при лечении ишемического инсульта у больных с окклюзией артерий крупного калибра / В.И. Скворцова [и др.] // Журнал неврологии и психиатрии им. С.С. Корсакова. - 2006. - Т. 106, № 12. - С. 32-40.
2. Системная тромболитическая терапия при ишемическом инсульте / В.И. Скворцова [и др.] // Журнал неврологии и психиатрии им. С.С. Корсакова. - 2006. - Т.106, № 12. - С.24-31.
3. Тромболитическая терапия при ишемическом инсульте: методич. пособие / Под ред. В. И. Скворцовой. - М.: НИИ цереброваскулярной патологии и инсульта ГБОУ ВПО РНИМУ им. Н.И. Пирогова МЗ РФ, 2011. - 48 с.
4. Expansion of the Time Window for Treatment of Acute Ischemic Stroke With Intravenous Tissue Plasminogen Activator. A Science Advisory From the American Heart Association/American Stroke Association / del Zoppo DJ. [et al.] // Stroke. - 2009. - Vol. 40. - P. 2945-2948.
5. Thrombolysis with Alteplase 3 to 4.5 Hours after Acute Ischemic Stroke / Hacke W. [et al.] // N Engl J Med. - 2008. - Vol. 359. - P. 1317-1329.
Review
For citations:
Chugunova S.A., Nikolayeva T.Y., Yakovlev A.A., Chemezov A.N. Systemic thrombolytic therapy of ischemic stroke. Clinical follow-up according to the Regional Vascular Center (Yakutsk) data. Yakut Medical Journal. 2013;(3):119-121.
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