Clinical and morphological characteristics of chronic gastritis with functional dyspepsia in the North

Abstract

The analysis of clinical–endoscopic manifestations of symptoms of functional dyspepsia in different ethnic groups, living in Republic Sakha (Yakutia) is carried out. At the analysis of clinical symptoms of functional dyspepsia patients with postprandial distress syndrome and epigastric pain syndrome are revealed. Clinical manifestation and course of chronic gastritis with functional dyspepsia in the Republic Sakha (Yakutia) have a number of distinctive features: among the surveyed epigastric pain syndrome occurs in patients of indigenous and non-indigenous population the intensity of pain in the indigenous is much lower than that of non-indigenous. Postprandial distress syndrome was diagnosed in 71, 9% of indigenous patients and 28, 1% of the nonindigenous. At endoscopy in all patients with functional dyspepsia chronic gastritis is diagnosed. The native inhabitants more frequently have mixed gastritis (54, 5%), the non-natives – superficial gastritis (66, 7%). At the epigastric pain syndrome continuous acid production and hyperacidity are detected more often in the non-indigenous (41, 4%) than in the indigenous population (9, 8%). At the postprandial distress syndrome in the indigenous normacidity is more common (45, 3%), in the non-indigenous – hyperacidity (14, 1%). At the syndrome of epigastric pain more effective was the prescription of anti-H. pylori and antisecretory drugs, and at postprandial distress syndrome – prokinetics, at the revealed hyperacidity therapy should be supplement with antisecretory agents.