Comparative analysis of immunogenetic determinants of HLA system A, B, C loci in the indigenous residents of the Khabarovsk territory, donors and psoriatic patients
Abstract
The paper gives the data of a study of HLA-antigens in 31 aborigens, 1600 donors, 85 patients with psoriasis. In aborigines (the Ulch) low frequency of HLA antigen A1 and tendency for increase of HLA B13 were found. Indices of HLA B-17 were the same as in the control group. In patients with psoriasis high frequency of antigens HLA A-1, HLA B-13, HLA B-17 and low frequency of antigens HLA A-28, B-7, Cw-3, Cw-4 was determined. This can point out the absence of genetic susceptibility for psoriasis in the Ulch.
About the Authors
A. V. Nekipelova
Postgraduate Institute for Public health Workers
Russian Federation
Russian Federation
Nekipelova Alla Vladimirovna - MD, assistant professor, dermatologist of the highest category
department of infectious diseases and dermatology
Khabarovsk
G. B. Kalatushkina
Clinical Hospital № 1
Russian Federation
Russian Federation
Kalatushkina Galina Borisovna - immunologist of the highest category
Khabarovsk
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Review
For citations:
Nekipelova A.V., Kalatushkina G.B. Comparative analysis of immunogenetic determinants of HLA system A, B, C loci in the indigenous residents of the Khabarovsk territory, donors and psoriatic patients. Yakut Medical Journal. 2013;(1):24-27.
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