Features of biophysical properties and composition of oral fluid in children with connective tissue dysplasia living in the conditions of high latitudes
Abstract
The article dwells on a comprehensive clinical and laboratory study of children with connective tissue dysplasia (CTD), living in the North. The findings suggest that the presence of certain changes in the composition and properties of the oral fluid, which leads to disruption of the structural homogeneity of hard tissue of teeth and reduce their caries. In the surveyed age groups of children biophysical properties of the oral fluid are characterized by a decrease in secretion rate, increased saliva viscosity, the prevalence of type II and III microcrystallisation, decrease of remineralizing potential of oral fluid. In the composition of saliva there were marked decrease in the total protein concentration in children with severe CTD, alkaline phosphatase activity, regardless of severity, concentrations of magnesium and calcium cations, which are essential in saturation by mineral components of tooth enamel hydroxyapatite.
The revealed features of the composition and properties of oral fluid can be considered as specific regional biological risk factors for the formation of pathological processes of organs and tissues of the oral cavity in children with CTD, living in the North.
About the Authors
E. U. NikiforovaRussian Federation
Nikiforova Ekaterina Ur’evna – Graduate student of the Department of medical, surgical, dental orthopedic dentistry and pediatric dentistry
677016, Yakutsk, St.Oyunskogo 27, 420 cabinet
I. D. Ushnitsky
Russian Federation
Ushnitsky Innokentiy Dmitriyevich – M.D., Professor, Head of the Department of medical, surgical, dental orthopedic dentistry and pediatric dentistry
677016, Yakutsk, St.Oyunskogo 27, 420 cabinet
A. M. Ammosova
Russian Federation
Ammosova Aelita Michailovna – P.h.D., Associate Professor of the Department of propaedeutics childhood diseases
677016, Yakutsk, St.Oyunskogo 27, 420 cabinet
A. D. Semenov
Russian Federation
Semenov Alexsandr Dmitriyevich – Chief Medical Officer
677016, Yakutsk, St.Oyunskogo 27, 420 cabinet
A. S. Cheremkina
Russian Federation
Cheremkina Anna Sergeevna – Senior Lecturer of the Department of medical, surgical, dental orthopedic dentistry and pediatric dentistry
677016, Yakutsk, St.Oyunskogo 27, 420 cabinet
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Review
For citations:
Nikiforova E.U., Ushnitsky I.D., Ammosova A.M., Semenov A.D., Cheremkina A.S. Features of biophysical properties and composition of oral fluid in children with connective tissue dysplasia living in the conditions of high latitudes. Yakut Medical Journal. 2016;(4):41-44.