Comparison of clinical and laboratory parameters in patients with endstage renal failure in the outcome of chronic glomerulonephritis and patients with end-stage renal failure in the outcome of other diseases
Abstract
We conducted a study to evaluate the hemostatic system parameters in patients with end-stage renal failure, depending on the cause of renal failure and hemodialysis treatment duration. It was revealed that the state of homeostasis in patients with end-stage renal failure characterizes the level of fibrinogen and the activation of the hemostatic markers: soluble fibrin monomer complexes, D-dimers. In patients with end-stage renal failure in the outcome of chronic glomerulonephritis, a great expression of activation of blood coagulation confirm the increased mean concentration of fibrinogen, whereas in the group, which included patients with end-stage renal failure in the outcome of other diseases (type 1 diabetes, type 2 diabetes, systemic disease, polycystic kidney disease, hypertensive nephroangiosclerosis, anomalies of development of kidneys, chronic pyelonephritis, urate nephropathy), such is not different from the norm, and a higher rate of hyperfibrinogenemia, identified in 2/3 patients in this group.
About the Authors
J. A. Popova
Medical Institute, “North-Eastern Federal University”
Russian Federation
Russian Federation
Popova Julia Alexeevna, graduate student
677008, Republic of Sakha (Yakutia), Yakutsk, Kalandarishvili 38/5 sq. 27. Phone: 89142767120
M. I. Krylova
Medical Institute, “North-Eastern Federal University”
Russian Federation
Russian Federation
Krylova Maria Ivanovna, Phypertinya, senior lecturer of “Hospital therapy, occupational diseases and Clinical Pharmacology Department”
V. N. Yadrihinskaya
Medical Institute, “North-Eastern Federal University”
Russian Federation
Russian Federation
Yadrihinskaya Vera Nikolaevna, Phypertinya, associate professor of “Hospital therapy, occupational diseases and clinical pharmacology Department”
N. V. Borisova
Medical Institute, “North-Eastern Federal University”
Russian Federation
Russian Federation
Borisova Natalia Vladimirovna, professor of “Normal and pathology physiology Department”
P. G. Petrova
Medical Institute, “North-Eastern Federal University”
Russian Federation
Russian Federation
Petrova Palmira Georgievna, chief of “Normal and pathology physiology Department”
N. E. Kardashevskaya
Medical Institute, «North-Eastern Federal University”
Russian Federation
Russian Federation
Kardashevskaya Nadezhda Egorovna, 5th year student
677008, Republic of Sakha (Yakutia), Yakutsk, Lenina 56 sq. 9. Phone: 89243694511
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Review
For citations:
Popova J.A., Krylova M.I., Yadrihinskaya V.N., Borisova N.V., Petrova P.G., Kardashevskaya N.E. Comparison of clinical and laboratory parameters in patients with endstage renal failure in the outcome of chronic glomerulonephritis and patients with end-stage renal failure in the outcome of other diseases. Yakut Medical Journal. 2016;(4):17-19.
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