Improvement of perinatal reserves in women with extragenital diseases
https://doi.org/10.1234/YMJ.2022.77.19
Abstract
Risk factors were determined and a prognostic model of adverse perinatal outcomes was constructed in a sample of pregnant women with extragenital diseases (EGD) (anemia, chronic pyelonephritis, chronic arterial hypertension) by logistic regression. The search for prognostic criteria is optimal in the comprehensive examination of pregnant women with EGD (assessment of microbiome, immune status, utero-fetal-placental blood flow and placental pathomorphology).
The morphology of the placenta reflects the fullness of embryo- and fetogenesis of women with EGD, mediated by the resources of the mother's body, optimal in the dogestational recovery and prevention of placental insufficiency in the early gestation. Prediction of the risks of perinatal outcomes and morbidity in pregnant women with EGD – anemia, CP and CAG is realizable using logistic regression model resources.
About the Authors
B. M. Gasanova
Peoples' Friendship University of Russia
Russian Federation
Russian Federation
Bakhtykey M. Gasanova – Candidate of Medical Sciences, Doctoral student, Medical Institute of the Peoples' Friendship University of Russia.
M. L. Polina
Medical Center for Women's Health
Russian Federation
Russian Federation
Miroslava L. Polina – PhD, Medical Center for Women's Health.
Moscow
N. I. Douglas
M.K. Ammosov Northeastern Federal University
Russian Federation
Russian Federation
Natalia I. Douglas – MD, Head of the Department, Medical Institute of the M.K. Ammosov Northeastern Federal University.
References
1. Apresyan S.V. Pregnancy and childbirth in extragenital diseases / ed. V.E. Radzinsky. 2nd ed., revised. and additional M.: GEOTAR-Media, 2015; 536 p.
2. Bondarenko K.R. The leading role of infection in the formation of placental insufficiency / Bondarenko K.R., Mavzyutov A.R., Ozolinya L.A. // Journal of microbiology, epidemiology and immunobiology. 2013; 4:3-9.
3. Bushtyreva I.O. Uteroplacental blood flow during the first wave of cytotrophoblast invasion in pathological pregnancy / Bushtyreva I.O., Kuznetsova N.B., Levchenko M.V. // Issues of gynecology, obstetrics and perinatology. 2012; 11(6): 30-33.
4. Voevodin S.M. Ultrasound and clinical and morphological assessment of placental dysfunction in critical conditions in the fetus / Voevodin S.M., Shemanaeva T.V., Dubova E.A. // Gynecology. 2013;15(5):65–69.
5. Kuznetsov R.A. Morphological criteria for primary placental insufficiency / Kuznetsov R.A., Peretyatko L.P., Rachkova O.V. // Bulletin of RUDN University. Series “Medicine. Obstetrics and gynecology". 2011; 5:34-39.
6. Prediction and early diagnosis of placental insufficiency in women of late reproductive age / Kryukova NI, Kulavsky V.A., Kryukov A.A., Frolov A.L. // Russian Bulletin of an obstetrician-gynecologist. 2013; 4:45-49.
7. Radzinsky V.E. Early pregnancy. From preconception preparation to healthy gestation / Radzinsky V.E., Orazmuradov A.A. // 3rd ed., rev. and additional M., Status Praesens. 2018; 800 p.
8. Contemporary characteristics of etiology and pathogenesis of fetal loss syndrome / Tirskaya YuI, Rudakova E.B., Shakina I.A. et al. // Ural Medical Journal. 2010;1(66):100-106. (In Russ.)
9. Tayupova I.M. The role of iron deficiency in the occurrence of infectious complications during pregnancy / Tayupova I.M., Sakhautdinova I.V., Almukhametova L.D. // Bulletin of RUDN University, Medicine series. Obstetrics and gynecology. 2012; 5:54-59.
10. Asymptomatic pyuria in pregnant women during the first trimester is associated with an increased risk of adverse obstetrical outcomes / Lai Y.J., Hsu T.Y., Lan K.C., et al. // Taiwan J Obstet Gynecol. 2017;56(2):192-195.
11. Cheesbrough M. District Laboatory Practice in Tropical Countries. Part 2. United States of America by Cambridge University Press. New York: Cambridge university press; 2006. Examinnation of urine; 105–15.
12. Hypertension in response to placental ischemia during pregnancy: role of B lymphocytes. LaMarca B, Wallace K, Herse F, et al. // Hypertension. 2011; 57(4):865–71.
13. Localization of cathepsins D and В at the maternalfetal interface and the invasiveness of the trophoblast during the postimplantation period in the mouse / Amarante-Paffaro A.M., Hoshida M.S., Yokota S, et al. // Cells Tissues Organs. 2011. 193 (6). 417-25.
14. Maternal and fetal outcome in women with hypertensive disorders of pregnancy: the impact of prenatal care / Barbosa I.R., Silva W.B., Cerqueira G.S., et al. // Ther Adv Cardiovasc Dis. 2015;9(4):140-6.
15. Matuszkiewicz-Rowińska J. Urinary tract infections in pregnancy: old and new unresolved diagnostic and therapeutic problems / Matuszkiewicz-Rowińska J, Małyszko J, Wieliczko M. // Arch Med Sci. 2015;11(1):67-77.
16. Moreno Santillan A.A. Uric Acid in Pregnancy: New Concepts / Moreno Santillan A.A., Briones Garduño JC, Diaz de Leon Ponce M.A. // Contrib Nephrol. 2018;192:110-115.
17. Naresh A, Simhan H.N. Association of polymicrobial growth from urine culture with adverse pregnancy outcomes. Am J Perinatol. 2011;28(7):537-42.
18. Placental changes in pregnancy induced hypertension / Nahar L, Nahar K, Hossain M.I, et al. // Mymensingh Med J. 2013;22(4):684-93.
19. Viral infection of the placenta leads to fetal inflammation and sensitization to bacterial products predisposing to preterm labor // Cardenas I, Means R.E., Aldo P, et al. // J Immunol. 2010; 185:1248–1257.
Review
For citations:
Gasanova B.M., Polina M.L., Douglas N.I. Improvement of perinatal reserves in women with extragenital diseases. Yakut Medical Journal. 2022;(1):75-79. https://doi.org/10.1234/YMJ.2022.77.19
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