The association of insulin resistance and visceral adipose tissue dysfunction with components of metabolic syndrome in men of Western-Yakut industrial region
Abstract
We have compared the association of parameters of insulin resistance and visceral fat dysfunction with the main and additional components of metabolic syndrome in men who permanently reside in West Yakutia industrial region and work in mining company. There was a close connection between insulin resistance and analyzed main and additional components of metabolic syndrome. However, we have found no association between the dysfunction of visceral fat tissue and disorders of carbohydrate metabolism, which is the principal component of metabolic syndrome. Cardiometabolic risk assessment using the criteria of visceral fat dysfunction can therefore result in underestimated contribution of carbohydrate metabolism disorder to cardiometabolic risk. Thus, insulin resistance criteria are more informative in population studies of metabolic syndrome epidemiology and pathogenesis than the criterion of visceral fat tissue dysfunction.
About the Authors
Yu. V. Lutov
Research Institute of Experimental and Clinical Medicine
Russian Federation
Russian Federation
PhD, Senior Researcher of Laboratory of Endocrinology
630117, Novosibirsk, Timakov st., 2
V. G. Selyatitskaya
Research Institute of Experimental and Clinical Medicine
Russian Federation
Russian Federation
Doctor of Biological Sciences, Professor, Chief Researcher of Laboratory of Endocrinology
630117, Novosibirsk, Timakov st., 2
D. A. Deev
Research Institute of Experimental and Clinical Medicine
Russian Federation
Russian Federation
Junior Researcher of Laboratory of Endocrinology
630117, Novosibirsk, Timakov st., 2
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Review
For citations:
Lutov Yu.V., Selyatitskaya V.G., Deev D.A. The association of insulin resistance and visceral adipose tissue dysfunction with components of metabolic syndrome in men of Western-Yakut industrial region. Yakut Medical Journal. 2016;(2):32-34.
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