The correlation between collagen and lipid metabolisms in residents of the Arctic Zone of the Russian Federation
Abstract
We represent the results of the study of apparently healthy men, the overweight northerners. We observed increased fibrosis, combined with local regulation system activation, which was manifested as an increase in the content of matrix metalloproteinases (MMP-1 and MMP-9) and tissue inhibitors of matrix metalloproteinases (TIMP-1 and TIMP-4). The revealed correlations between forms of hydroxyproline and cardiovascular risk factors indicate the relationship of collagen metabolism and atherogenesis.
About the Authors
E. B. Kim
FGBNU «Institute of Experimental and Clinical Medicine»
Russian Federation
Russian Federation
Kim Elena Borisovna - Chief Researcher, Head of the connective tissue biochemistry group, MD, Associate Professor
630117, Timakov Street, 2, Novosibirsk
A. N. Putiatina
FGBNU «Institute of Experimental and Clinical Medicine»
Russian Federation
Russian Federation
Putiatina Anna Nikolaevna - Researcher, PhD
630117, Timakov Street, 2, Novosibirsk
P. M. Kozhin
FGBNU «Institute of Experimental and Clinical Medicine»
Russian Federation
Russian Federation
Kozhin Pyotr Mikhailovich – researcher
630117, Timakov Street, 2, Novosibirsk
M. M. Gevorgyan
FGBNU «Institute of Experimental and Clinical Medicine»
Russian Federation
Russian Federation
Gevorgyan Margarita Mailovna - Head of clinical and diagnostic department, PhD
630117, Timakov Street, 2, Novosibirsk
G. S. Russkikh
FGBNU «Institute of Experimental and Clinical Medicine»
Russian Federation
Russian Federation
Russkikh Galina Sergeevna - researcher; PhD
630117, Timakov Street, 2, Novosibirsk
N. P. Voronina
FGBNU «Institute of Experimental and Clinical Medicine»
Russian Federation
Russian Federation
Voronina Natalia Petrovna - doctor of clinical laboratory diagnostics; PhD (Biology)
630117, Timakov Street, 2, Novosibirsk
T. V. Kozaruk
FGBNU «Institute of Experimental and Clinical Medicine»
Russian Federation
Russian Federation
Kozaruk Tatiana Vladimirovna - doctor of clinical laboratory diagnostics
630117, Timakov Street, 2, Novosibirsk
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Review
For citations:
Kim E.B., Putiatina A.N., Kozhin P.M., Gevorgyan M.M., Russkikh G.S., Voronina N.P., Kozaruk T.V. The correlation between collagen and lipid metabolisms in residents of the Arctic Zone of the Russian Federation. Yakut Medical Journal. 2016;(2):5-8.
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