The Prevalence of HPV Infection in Patients with Cervical Cancer and Dysplasia in Yakutia
Abstract
The research was conducted among 164 women from the Sakha Republic (Yakutia) (of average age of 44.6+/- 0.82) diagnosed with histologically verified IIIrd degree dysplasia (CIN III) and uterine neck cancer. Analysis of HPV-contamination of high oncogenous risk among women with uterine neck cancer pathologies showed 78.10 % of HPV DNA detected from the total of 164 female patients. Genotyping assay of HPV-positive samples showed that Type 16 HPV is the most common one (82.81 %).
About the Authors
N. N. Makarova
YSC CMP SB RAMS; NEFU named after M.K. Ammosov
Russian Federation
Russian Federation
Makarova Natalia N., PhD, Senior Scientist YSC CMP SB RAMS, Head of Yakut Repub. Oncology Center, Associate Professor MI NEFU named after M.K. Ammosov
L. N. Urazova
Tomsk Cancer Research Center of SB RAMS
Russian Federation
Russian Federation
Urazova Lyudmila N., Biology Dr., prof., Head of lab.
L. F. Pisareva
Tomsk Cancer Research Center of SB RAMS
Russian Federation
Russian Federation
Pisareva Lyubov’ F. – MD, prof., chief researcher
P. M. Ivanov
YSC CMP SB RAMS; MI NEFU named after M.K. Ammosov
Russian Federation
Russian Federation
Ivanov Pyotr M. - MD. prof., head of the laboratory YSC CMP SB RAMS, Head of oncology course MI NEFU named after M.K. Ammosov
S. A. Myreeva
YSC CMP SB RAMS; YAROD
Russian Federation
Russian Federation
Myreeva Svetlana A., PhD, research assistant YSC CMP SB RAMS, gynecologist-oncologist YAROD
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Review
For citations:
Makarova N.N., Urazova L.N., Pisareva L.F., Ivanov P.M., Myreeva S.A. The Prevalence of HPV Infection in Patients with Cervical Cancer and Dysplasia in Yakutia. Yakut Medical Journal. 2014;(2):93-95.
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