Subjective cognitive and subtle cognitive impairments
https://doi.org/10.25789/YMJ.2022.79.21
Abstract
Cognitive impairments are one of the leading problems of neurology and psychiatry due to their wide prevalence, especially in the elderly and senile age, the difficulty in diagnosis and treatment. In addition, the increase in life expectancy of the population in Russia and in the world will undoubtedly cause a rapid increase in patients with dementia and other cognitive impairments. However, dementia in most cases does not develop overnight; its development is preceded by a long period of time when the existing cognitive impairments do not yet disrupt the patient's household and professional activity. Cognitive impairment of this degree is called "pre-dementia" and is divided into subjective cognitive decline, subtle and mild cognitive impairments. This article discusses the key problems of subjective cognitive decline and subtle cognitive impairment, the interpretation and diagnosis of which raises the most frequent questions among clinicians. So, based on a review of Russian and foreign literature, the authors substantiate how it is possible to distinguish between subjective cognitive decline and subtle cognitive impairment, and discuss where the line with moderate cognitive impairment is. Separately, diagnostic algorithms and treatment tactics for subjective cognitive decline and subtle cognitive impairment are presented.
About the Authors
A. A. Tappakhov
Medical Institute, M.K. Ammosov North-Eastern Federal University
Russian Federation
Russian Federation
Tappakhov Alexey A – PhD, Associate Professor at the Department of Neurology and Psychiatry
Т. Е. Popova
Scientific Center for Complex Medical Problems
Russian Federation
Russian Federation
Popova Tatyana E – MD, deputy Director for Science
Yakutsk
References
1. Vakhnina N.V. Vascular cognitive impairments / N.V. Vakhnina // Neurology, neuropsychiatry, psychosomatics. – 2014. – Vol. 1. – P. 74-79. DOI:10.14412/2074-2711-2014-1-74-79
2. Zakharov V.V. Non-demented cognitive impairment: subjective, subtle and mild / V.V. Zakharov, Kabaeva A.R. // Nervous diseases. – 2017. – Vol. 4. – P. 3-9.
3. Zakharov V.V. Prevention of dementia in patients with mild cognitive impairment / V.V. Zakharov, M.S. Novikova, A.R. Kabaeva // S.S. Korsakov Journal of Neurology and Psychiatry. – 2020. – T. 120, Vol. 8. – P. 167-174. DOI:10.17116/jnevro2020120081167
4. Clinical guidelines “Cognitive disorders in elderly and senile patients” / A.N. Bogolepova, E.E. Vasenina, A.A. Gomzyakova [et al.] // S.S. Korsakov Journal of Neurology and Psychiatry. – 2021. – T. 121, Vol. 10. – 141 p.. DOI:10.17116/jnevro20211211036
5. Koberskaya N.N. Modern concept of cognitive reserve / N.N. Koberskaya, G.R. Tabeeva // Neurology, neuropsychiatry, psychosomatics. – 2019. – Vol. 11(1). – P. 96-102. DOI:10.14412/2074-2711-2019-1-96-102
6. Levin O.S. Pre-dementia neurocognitive disorders in the elderly / O.S. Levin // S.S. Korsakov Journal of Neurology and Psychiatry. – 2019. – T. 119, Vol. 9. – P. 10-17. DOI:10.17116/jnevro201911909210
7. Lobzin V.Yu. A new look at the pathogenesis of Alzheimer's disease: modern ideas about amyloid clearance / V.Yu. Lobzin, K.A. Kolmakova, A.Yu. Emelin // Review of Psychiatry and Medical Psychology. - 2018. - No. 2. - P. 22-28. doi :10.31363/2313-7053-2018-2-22-28
8. Pre-dementia conditions and dementia in young people / A.A. Smirnov, A.V. Gustov, S.V. Kopishinskaya [et al.] // Neurology, neuropsychiatry, psychosomatics. – 2014. – Vol. 2. – P. 41- 43. DOI:10.14412/2074-2711-2014-2-41-43
9. Pre-mild (subjective and subtle) cognitive impairments / N.N. Yakhno, V.V. Zakharov, N.N. Koberskaya [et al.] // Neurological journal. – 2017. – Vol. 4. – P. 198 - 204. DOI:10.18821/1560-9545-2017-22-4-198-204
10. Starchina Yu.A. Non-demented cognitive impairment: a modern view of the problem / Yu.A. Starchina // Neurology, neuropsychiatry, psychosomatics. – 2017. – Vol. 9 (2). – P. 71-76. DOI:10.14412/2074-2711-2017-2-71-76
11. Yakupov E.Z. Subtle cognitive impairment – more questions than answers / E.Z. Yakupov, R.A. Zhamieva // Neurological Bulletin. – 2021. – T. LIII, Vol. 2. – P. 71-80. DOI:10.17186/nb71485
12. Yakhno N.N. Cognitive disorders in the neurological clinic / N.N. Yakhno // Neurological journal. – 2006. – Vol. 11, Appendix No. 1. – P. 4 - 12.
13. A conceptual framework for research on subjective cognitive decline in preclinical Alzheimer’s disease / F. Jessen, R. Amariglio, M. Van Boxtel [et al.] // Alzheimer’s Dement. – 2014. – Vol. 10(6). – P. 844 - 852. doi:10.1016/j.jalz.2014.01.001
14. Alzheimer’s disease: clinical update on epidemiology, pathophysiology and diagnosis / D. Eratne, S.M. Loi, S. Farrand [et al.] // Australas Psychiatry. – 2018. – Vol. 26(4). – P. 347-357. doi:10.1177/1039856218762308
15. Cognitive reserve, Alzheimer’s neuropathology, and risk of dementia: a systematic review and meta-analysis / M.E. Nelson, D.J. Jester, A.J. Petkus [et al.] // Neuropsychol Rev. – 2021. – Vol. 31(2). – P. 233-250. doi:10.1007/s11065-021-09478-4
16. Comparison of the short test of mental status and the Mini-mental state examination in mild cognitive impairment / D.F. Tang-Wai, D.S. Knopman, Y.E. Geda [et al.] // Arch Neurol. – 2003. – Vol. 60(12). – P. 1777. doi:10.1001/archneur.60.12.1777
17. Is the Montreal Cognitive Assessment (MoCA) test better suited than the Mini-Mental State Examination (MMSE) in mild cognitive impairment (MCI) detection among people aged over 60? Meta-analysis / N. Ciesielska, R. Sokołowski, E. Mazur [et al.] // Psychiatr Pol. – 2016. – Vol. 50(5). – P. 1039-1052. doi:10.12740/pp/45368
18. Lancu I. The minimental state examination--an up-to-date review / I. Lancu, A. Olmer // Harefuah. – 2006. – Vol. 145(9). – P. 687-690.
19. Subjective cognitive decline and risk of MCI: The Mayo Clinic Study of Aging / A.C. van Harten, M.M. Mielke, D.M. Swenson-Dravis [et al.] // Neurology. – 2018. – Vol. 91(4). – P. e300-e312. doi:10.1212/WNL.0000000000005863
20. Subjective cognitive decline: preclinical manifestation of Alzheimer’s disease / L. Yan, S. Pei, J. Wen [et al.] // Neurol Sci. – 2019. – Vol. 40(1). – P. 41-49.
21. The Global Deterioration Scale for assessment of primary degenerative dementia / B. Reisberg, S.H. Ferris, M.J. De Leon [et al.] // Am J Psychiatry. – 1982. – Vol. 139(9). – P. 1136- 1139. doi:10.1176/ajp.139.9.1136
22. The global prevalence of dementia: A systematic review and metaanalysis / M. Prince, R. Bryce, E. Albanese [et al.] // Alzheimer’s Dement. – 2013. – Vol. 9(1). – P. 63-75. doi:10.1016/j.jalz.2012.11.007.
Review
For citations:
Tappakhov A.A., Popova Т.Е. Subjective cognitive and subtle cognitive impairments. Yakut Medical Journal. 2022;(3):81-85. https://doi.org/10.25789/YMJ.2022.79.21
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