Capabilities of Graphene Oxide Application as a Nanostructured Quencher at the Development of New Fluorescent Test Systems for DNA-Diagnostics
Abstract
Review is devoted to the description of the world’s approaches of using graphene oxide as a nanostructured quencher for DNA diagnostics of SNPs. The unique properties of graphene oxide with respect to DNA and detailed options for its use as a replacement for molecular quenchers in classical test systems are described. The potential for adaptation of existing approaches for the laboratory DNA-diagnostic is considered.
Supporting agencies: This work was supported by the Federal Program "Research and development on priority directions of scientific-technological complex of Russia in 2014 - 2020 years" of Russian Ministry of Education and Science (grant № 14.575.21.0015).
About the Authors
A. A. Kuznetsov
Medical Institute, NEFU named after M.K. Ammosov; YSC CMP SB RAMS
Russian Federation
Russian Federation
Kuznetsov Artem Aleksandrovich –engineer-researcher of Laboratory of Genome Medicine, Clinics, research associate
N. R. Maksimova
Clinics of Medical Institute, NEFU named after M.K. Ammosov
Russian Federation
Russian Federation
Maksimova Nadezda Romanovna, Head of Laboratory of Genome Medicine
G. N. Aleksandrov
NEFU named after M.K. Ammosov
Russian Federation
Russian Federation
Alexandrov Grigory Nikolaevich, research associate of Graphene Nanotechnology Laboratory
S. A. Smagulova
NEFU named after M.K. Ammosov
Russian Federation
Russian Federation
Smagulova Svetlana Afanasievna, Head of Graphene Nanotechnology Laboratory
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Review
For citations:
Kuznetsov A.A., Maksimova N.R., Aleksandrov G.N., Smagulova S.A. Capabilities of Graphene Oxide Application as a Nanostructured Quencher at the Development of New Fluorescent Test Systems for DNA-Diagnostics. Yakut Medical Journal. 2014;(4):74-78.
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