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Use of phyto-adaptogens to correct cold effects on the body

https://doi.org/10.25789/YMJ.2018.62.06

Abstract

The purpose of this research was to study the possibility of using a mixture of phytoadaptogens for the correction of the body’s compensatory responses to the conditions of low temperatures.Experiments have been conducted on experimental animals (50 white mongrel rats-males weighing 180-200 g) in accordance with generally accepted methodological approaches. Research of cold adaptation reactions of experimental animals have been conducted by using the model of a long cold action with appropriate climatic chamber.It was established experimentally that in doses of 150-300 mg/kg daily of the studied mixture has a strong antioxidant effect in the conditions of cold stress on warm-blooded organism. The research allowsusing a mixture of phytoadaptogens as а regulator of adaptive reactions of the organism when exposed to low temperatures.

About the Authors

E. V. Slobodenyuk
Far Eastern State Medical University
Russian Federation

Elena V. Slobodenyuk, Dean of the faculty of pharmacy, Doctor of Biological Sciences, Associate Professor, Head of the Department of Pharmacology and Clinical Pharmacology

Khabarovsk



E. A. Litovchenko
Amur State Medical Academy
Russian Federation

Ekaterina A. Litovchenko, MD, Postgraduate student of Department of General Hygiene

95 Gor’kogo Str., Blagoveshchensk, 675000



N. V. Korshunova
Amur State Medical Academy
Russian Federation

Natalia V. Korshunova, MD, PhD, DSc, Professor, Head of Department of General Hygiene

95 Gor’kogo Str., Blagoveshchensk, 675000

mob. 89246729557



M. A. Shtarberg
Amur State Medical Academy
Russian Federation

Mikhail A. Shtarberg, candidate of medical Sciences, senior researcher 

95 Gor’kogo Str., Blagoveshchensk, 675000



References

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2. Dorovskikh V.A., Simonova N.V., Korshunova N.V. Adaptogeny v regulyatsii kholodovogo stressa [Adaptogens in the regulation of cold stress]. Saabrucken: Palmarium academic publishing, 2013, 248 p.

3. Kim L.B. Transport kisloroda pri adaptacii cheloveka k uslovijam Arktiki i kardiorespiratornoj patologii [The transport of oxygen in human adaptation to Arctic conditions and cardiorespiratory diseases]. Novosibirsk: NII jeksperimental’noj i klinicheskoj mediciny [Novosibirsk: Scientific research Institute of experimental and clinical medicine], 2015, 216 p.

4. Korshunova N.V. Toksikologogigienicheskoe obosnovanie ispol’zovanija produktov pererabotki pantov dlja povyshenija rezistentnosti organizma k holodu [Toxicological and hygienic justification of using products of processing of antlers for increase of resistance of an organism to cold]. SanktPeterburg [Saint-Petersburg], 2001, 39 p.


Review

For citations:


Slobodenyuk E.V., Litovchenko E.A., Korshunova N.V., Shtarberg M.A. Use of phyto-adaptogens to correct cold effects on the body. Yakut Medical Journal. 2018;(2):21-22. https://doi.org/10.25789/YMJ.2018.62.06

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ISSN 1813-1905 (Print)
ISSN 2312-1017 (Online)