Clinical case of acute myocardial infarction in the onset of chronic myeloproliferative disease
https://doi.org/10.25789/YMJ.2018.62.39
Abstract
The main clinical problem of patients with chronic myeloproliferative diseases are thrombotic complications causing death and invalidism. Possible long-term latent course of these diseases, comorbid cardiovascular pathology increases the risk of fatal complications. This article presents a clinical case of chronic myeloproliferative disease in a 57-aged man, who first manifested with acute Q-positive myocardial infarction. The patient successfully underwent recanalization, transluminal balloon angioplasty with stenting of the anterior descending coronary artery. Based on thrombocytosis and bone marrow examination he fulfill the diagnosis of essential thrombocythemia. During follow-up of three years, the progression of disease is observed with the development of secondary myelofibrosis. The diagnosis is confirmed by bone marrow histology and taking into account high risk of recurrent thrombotic complications, he administered with cytoreductive and antiplatelet therapy.
About the Authors
Kh. A. Kurtanov
YNC KMP
Russian Federation
Russian Federation
Kurtanov Khariton Alekseevich – PhD, Chief scientific officer - Head of the Department of Molecular Genetics
Tel.: +7 (914) 106 00 30
T. N. Alexandrova
YNC KMP
Russian Federation
Russian Federation
Aleksandrova Tuiara Nikonovna – junior researcher of the laboratory of heritable pathology
N. I. Pavlova
YNC KMP
Russian Federation
Russian Federation
Pavlova Nadezhda Ivanovna – PhD, temporary acting chief scientific officer - head of the laboratory of heritable pathology
I. I. Mulina
YNC KMP
Russian Federation
Russian Federation
Mulina Inna Ivanovna – Head of the Department of hematology National Centre of Medicine
I. E. Solovyeva
YNC KMP
Russian Federation
Russian Federation
Solovieva Irina Eremeevna – hematologist of National Centre of Medicine
M. A. Varlamova
YNC KMP
Russian Federation
Russian Federation
Varlamova Marina Alekseevna – junior researcher of the laboratory of heritable pathology;
L. M. Neustroeva
YNC KMP
Russian Federation
Russian Federation
Neustroeva Lena Mikhaylovna – junior researcher of the laboratory of the Laboratory of Population Genetics
A. T. Dyakonova
YNC KMP
Russian Federation
Russian Federation
D’yakonova Aleksandra Timofeevna – junior researcher of the laboratory of heritable pathology
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Review
For citations:
Kurtanov Kh.A., Alexandrova T.N., Pavlova N.I., Mulina I.I., Solovyeva I.E., Varlamova M.A., Neustroeva L.M., Dyakonova A.T. Clinical case of acute myocardial infarction in the onset of chronic myeloproliferative disease. Yakut Medical Journal. 2018;(2):120-122. https://doi.org/10.25789/YMJ.2018.62.39
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