Some bioethical issues of molecular genetic diagnosis of autosomal recessive deafness of 1 A type common in the Yakut population
https://doi.org/10.25789/YMJ.2018.62.23
Abstract
Autosomal recessive deafness 1A is one of the most frequent hereditary diseases in the Republic Sakha (Yakutia). The diagnosed features of spectrum and frequency of pathogenic variants in the GJB2 gene by the patients with congenital hearing loss allow applying routine DNA diagnostics in medical practice. In the article some bioethical issues of DNA testing of autosomal recessive deafness-1A are discussed.
About the Authors
S. K. Kononova
Yakut Scientific Centre of Complex Medical Problems
Russian Federation
Russian Federation
Kononova Sardana Kononova - senior researcher of the laboratory of molecular genetics
Yakutsk
N. A. Barashkov
Yakut Scientific Centre of Complex Medical Problems
Russian Federation
Russian Federation
Barashkov Nikolay Alekseevich -head of the laboratory of molecular genetics
Yakutsk
V. G. Pshennikova
Yakut Scientific Centre of Complex Medical Problems
Russian Federation
Russian Federation
Pshennikova Vera Gennadevna - researcher of the laboratory of molecular genetics
Yakutsk
A. V. Solovyev
Yakut Scientific Centre of Complex Medical Problems
Russian Federation
Russian Federation
Solovyev Aysen Vasilevich - researcher of the laboratory of molecular biology
Yakutsk
A. M. Cherdonova
M.K. Ammosov North-Eastern Federal University
Russian Federation
Russian Federation
Cherdonova Alexandra Matveevna – student
Yakutsk
A. A. Nikanorova
Yakut Scientific Centre of Complex Medical Problems
Russian Federation
Russian Federation
Nikanorova Alena Aphanasevna - researcher of the laboratory of molecular genetics
Yakutsk
G. P. Romanov
M.K. Ammosov North-Eastern Federal University
Russian Federation
Russian Federation
Romanov Georgy Prokopevich - researcher of the laboratory of molecular biology
Yakutsk
E. K. Khusnutdinova
Institute of biochemistry and genetics, Ufa Federal Research Center
Russian Federation
Russian Federation
Khusnutdinova Elsa Kamilevna - doctor of biological sciences , professor, academician of the Academy of Sciences of the Republic of Bashkortostan, Director
Ufa
S. A. Fedorova
M.K. Ammosov North-Eastern Federal University
Russian Federation
Russian Federation
Fedorova Sardana Arkadyevna - doctor of biological sciences, head of the laboratory of molecular biology
Yakutsk
F. M. Teryutin
M.K. Ammosov NorthEastern Federal University
Russian Federation
Russian Federation
Teryutin Fedor Michaylovich - senior researcher of the laboratory of molecular biology
Yakutsk
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Review
For citations:
Kononova S.K., Barashkov N.A., Pshennikova V.G., Solovyev A.V., Cherdonova A.M., Nikanorova A.A., Romanov G.P., Khusnutdinova E.K., Fedorova S.A., Teryutin F.M. Some bioethical issues of molecular genetic diagnosis of autosomal recessive deafness of 1 A type common in the Yakut population. Yakut Medical Journal. 2018;(2):79-82. https://doi.org/10.25789/YMJ.2018.62.23
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