The frequency of lipid metabolism disorders among the indigenous population of the Arctic zone of Yakutia
https://doi.org/10.25789/YMJ.2018.62.10
Abstract
One-stage population studies of biochemical markers of the lipid transport function of the indigenous population in the Arctic, Central and Southern zones of Yakutia have been carried out. An increase in the content of triglycerides and cholesterol and atherogenic fractions of lipids in the population from the north to the south was noted. Atherogenic changes in lipid metabolism are more pronounced in the arctic Yakuts, than in Dolgans, living in the same zone, and Evens of the Southern zone, which indicates a lower susceptibility to a disadaptive change in lipid metabolism in the Dolgans and the Evens.
About the Authors
L. D. Olesova
FSBSI «Yakut Scientific Center of Complex Medical Problems»
Russian Federation
Russian Federation
Olesova Ljubov’ Dygynovna, PhD (Biology), head of Laboratory of Biochemical Research
677010, Yakutsk, Sergelyakhskoye shosse, 4
G. E. Mironova
North-Eastern Federal University. M.K. Ammosov
Russian Federation
Russian Federation
Mironova Galina Egorovna, Doctor of Biological Sciences, Professor of Biological Branch of Institute of Natural Sciences
Yakutsk, Belinskogo, 58
Z. N. Krivoshapkina
FSBSI «Yakut Scientific Center of Complex Medical Problems»
Russian Federation
Russian Federation
Krivoshapkina Zoya Nikolaevna, PhD (Biology), Senior Researcher, Department for studying adaptation mechanisms
677010, Yakutsk, Sergelyakhskoye shosse, 4
E. I. Semenova
FSBSI «Yakut Scientific Center of Complex Medical Problems»
Russian Federation
Russian Federation
Semenova Evgenija Ivanovna, PhD (Biology), Senior Researcher, Department of the study of adaptation mechanisms
677010, Yakutsk, Sergelyakhskoye shosse, 4
S. I. Sofronova
FSBSI «Yakut Scientific Center of Complex Medical Problems»
Russian Federation
Russian Federation
Sofronova Sargylana Ivanovna, PhD (Medicine), head of Scientific-organizational and information publishing Department
677010, Yakutsk, Sergelyakhskoye shosse, 4
A. I. Yakovleva
FSBSI «Yakut Scientific Center of Complex Medical Problems»
Russian Federation
Russian Federation
Yakovleva Alexandra Ivanovna, Senior Researcher, Department of the study of adaptation mechanisms
677010, Yakutsk, Sergelyakhskoye shosse, 4
A. V. Efremova
FSBSI «Yakut Scientific Center of Complex Medical Problems»
Russian Federation
Russian Federation
Efremova Agrafena Vladimirovna, PhD (Biology), Department for studying adaptation mechanisms
677010, Yakutsk, Sergelyakhskoye shosse, 4
L. I. Konstantinova
FSBSI «Yakut Scientific Center of Complex Medical Problems»
Russian Federation
Russian Federation
Konstantinova Lena Ivanovna, Researcher, Department for studying adaptation mechanisms
677010, Yakutsk, Sergelyakhskoye shosse, 4
E. D. Okhlopkova
FSBSI «Yakut Scientific Center of Complex Medical Problems»
Russian Federation
Russian Federation
Okhlopkova Elena Dmitrievna - PhD (Biology), Leading researcherhead of the laboratory of immunological studies, Department for studying adaptation mechanisms
677010, Yakutsk, Sergelyakhskoye shosse, 4
References
1. Bojko E.R. Fiziologo-biohimicheskie i antropoehkologicheskie osnovy zhiznedeyatel’nosti cheloveka na Severe [Physiological, biochemical and anthropoecological basics of human activity in the North]. Ekaterinburg: NISO UrO RAN, 2005, 189 p.
2. Gafarov V. V. et al. Lichnostnaya trevozhnost’ i ishemicheskaya bolezn’ serdca [Personal anxiety and coronary heart disease] Ter. Arhiv [Ther. archive]. Moscow, 2005, № 12, p. 25 – 29.
3. Ivanova A.A. Sravnitel’nyj analiz obshchej smertnosti naseleniya razlichnyh grupp rajonov Respubliki Saha (YAkutiya) v 2010 g [Comparative analysis of the overall mortality of the population of various groups of the Sakha (Yakutia) regions in 2010] Dal’nevostochnyj medicinskij zhurnal [Far Eastern Medical Journal]. Khabarovsk, 2012, № 4, p.109.
4. Kaznacheev V.P. Sovremennye aspekty adaptacii [Modern aspects of adaptation]. Novosibirsk: Nauka, 1980, 191 p.
5. Kolesnikova L. I., Darenskaya M. A., Grebenkina L. A. et al. Problemy jetnosa v medicinskih issledovanijah [Ethnos problems in medical researches] Bjulleten’ VSNC SO AN [Bulletin of the East Siberian Scientific Center SB RAMS]. Novosibirsk, 2013, № 4 (92), p. 153–171.
6. Klimov A. N., Nikul’cheva N. G. Obmen lipidov i lipoproteidov i ego narusheniya : rukovodstvo dlya vrachej [Metabolism of the lipids and lipoproteins and its disorders]. SPb. : Piter Kom, 1999, p. 365.
7. Manchuk V. T. Ehtnicheskie i ehkologicheskie faktory v razvitii patologii u korennogo naseleniya Severa i Sibiri [Ethnic and environmental factors in the development of pathology in the indigenous population of the North and Siberia] Byulleten’ SO RAMN [Bulletin of the SB RAMS]. 2012, № 1, p. 93–98.
8. Panin L.E. Ehnergeticheskie aspekty adaptacii [Energy aspects of adaptation]. Leningrad, 1978, 190 p.
9. Panin L.E. Gomeostaz i problemy pripolyarnoj mediciny (metodologicheskie aspekty adaptacii) [A homeostasis and problems of subpolar medicine (methodological aspects of adaptation)] Byulleten’ SO RAMN [Bulletin of the Russian Academy of Medical Science]. Novosibirsk, 2010, V. 30, № 3, p. 6-11.
10. Egorova A.G., Krivoshapkina Z.N., Matveeva N.P. et al. Psihoehmocional’nye faktory i ih svyaz’ s dislipidemiej u trudosposobnogo naseleniya [Psychoemotional factors and their relationship with dyslipidemia in the able-bodied population].Yakutskij medicinskij zhurnal [Yakut medical journal]. Yakutsk, 2009, № 4. p. 57-60.
11. Savvinov G. N. Jekosistemy yakutskoj Arktiki v usloviyah sovremennogo prirodopol’zovaniya i transformacii klimata [Ecosystems of the Yakutian Arctic in conditions of modern nature management and climate transformation]. Vestnik SVFU [Herald NEFU]. Yakutsk, 2017, № 1 (57), p. 354- 43.
12. Strategiya razvitiya Arkticheskoj zony Rossijskoj Federacii i obespecheniya nacional’noj bezopasnosti na period do 2020 goda [Strategy for the development of the Arctic zone of the Russian Federation and ensuring national security for the period until 2020] (utv. Prezidentom RF) [ehlektronnyj dokument] URL: http//government.ru/ info/18360/ (data obrashcheniya [date of the application] 01.03.2018).
13. Tihonov D.G. Arkticheskaya medicina [Arctic medicine]. Yakutsk: Izdvo YANC SO RAN [Yakutsk: Publishing House of the Yakut Scientific Center SB RAS], Yakutsk, 2010, 317p.
14. Cukanov V.V., Tonkih Yu.L., Kupershtejn E.Yu. Rasprostranennost’ holelitiaza u mongoloidov i evropeoidov Sibiri [Cholelithiasis prevalence in Mongoloids and Caucasians] Voprosy sohraneniya i razvitiya zdorov’ya naseleniya Severa i Sibiri: mat. itogovoj nauch.-prakt. konf. Vyp. 5 [Problems of prevention and development of population health in the North and Siberia: proceedings of overall scientific-practical conference. Issue № 5]. Krasnoyarsk, 2006, p. 210–215.
15. Chashchin V. P. et al. Harakteristika osnovnyh faktorov riska narushenij zdorov’ya naseleniya, prozhivayushchego na territoriyah aktivnogo prirodopol’zovaniya v Arktike [Characteristics of the main risk factors of health disorders of the population living in the territories of active wildlife management in the Arctic] Jekologija cheloveka [Human Ecology]. Arhangel’sk, 2014, №1, p. 3-12.
16. Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults: Executive summary of the Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III). JAMA. 2001, 285 (19), pp. 2486-2497.
17. Friedwald W.T., Levy R.I., Fredrickson D.S. (1972) Estimation of the concentration of low-density lipoprotein cholesterol in plasma without use of preparative ultracentrifuge. Clin. Chem., 18(6): 499–502.
Review
For citations:
Olesova L.D., Mironova G.E., Krivoshapkina Z.N., Semenova E.I., Sofronova S.I., Yakovleva A.I., Efremova A.V., Konstantinova L.I., Okhlopkova E.D. The frequency of lipid metabolism disorders among the indigenous population of the Arctic zone of Yakutia. Yakut Medical Journal. 2018;(2):30-34. https://doi.org/10.25789/YMJ.2018.62.10
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