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The study of immunity in children with multiple papillomas

https://doi.org/10.25789/YMJ.2018.63.35

Abstract

In order to study the features of immunity in children with multiple papillomas and the effectiveness of therapy with groprinosin and lycopid drugs, a group of children with multiple papillomas and a group of healthy children, comparable in age, were examined. All children showed a positive PCR for HPV, a histological examination of the papillomas, as well as an examination of the immune status were done. It was revealed that in children with papillomas the content of IgA, CD19 + and CD16 + lymphocytes was reduced. The therapy with groprinosin and lycopid medications leads to normalization of the lowered immune status indicators, as well as to the cessation of the appearance of new papillomas in children.

About the Authors

O. N. Ivanova
NEFU
Russian Federation

Ivanova Olga Nikolaevna -doctor of medical sciences, Professor of Pediatrics and pediatric surgery Department



E. F. Argunova
MI NEFU
Russian Federation

Argunova Elena Filippovna – candidate of medical Sciences, associate Professor of Pediatrics and pediatric surgery



T. G. Dmitrieva
NEFU
Russian Federation

Dmitrieva Tatyana Gennadievna - doctor of medical sciences, Professor of Pediatrics and pediatric surgery Department



Ya. A. Munchalova
Medical Institute of NEFU
Russian Federation

Munkhalova Yana Afanasievna - Candidate of Medical Sciences, Head of the Department of Pediatrics and Pediatric Surgery



V. B. Egorova
Medical Institute of NEFU
Russian Federation

Egorova Vera Borisovna - Candidate of Medical Sciences, Associate Professor of the Department of Pediatrics and Pediatric Surgery



S. N. Alekseeva
Medical Institute of NEFU
Russian Federation

Alekseeva Sargylana Nikolaevna - Candidate of Medical Sciences, Associate Professor of the Department of Pediatrics and Pediatric Surgery



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Review

For citations:


Ivanova O.N., Argunova E.F., Dmitrieva T.G., Munchalova Ya.A., Egorova V.B., Alekseeva S.N. The study of immunity in children with multiple papillomas. Yakut Medical Journal. 2018;(3):107-109. https://doi.org/10.25789/YMJ.2018.63.35

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ISSN 1813-1905 (Print)
ISSN 2312-1017 (Online)