The detectability of Helicobacter pylori CAGA strain in adults and children according to the data of RH№1-NCM

The Republic of Sakha (Yakutia) belongs to Arctic territories. Hard social and economic conditions cause broad development of helicobacter infection in the republic. A comparative analysis of detectability of Helicobacter pylori CagA strain among adults and children with chronic gastritis since 2012 to 2016 according to Republic hospital №1 - National center of medicine (RH №1-NCM) revealed a distinct decrease in these indexes among adults and children with chronic gastritis. Thus it demands its further identification and treatment for prevention of stomach diseases of oncological risk group. This article presents research data of detectability of Helicobacter pylori among adults and children for 6 years in RH №1- NCM clinical-immunological laboratory by method of enzyme immunoassay on antibodies to antigen Cag A Helicobacter pylori. The blood serum of patients from the National center of medicine was the material for this research.

15868 patients were examined, 6993 of them were revealed Helicobacter pylori Cag A that made 44,1%. The detectability for the research period decreased from 49,6% to 40%. 3827 adults out of 8272 patients were revealed Нр (+) Cag A that made 46,3%, and detectability decreased from 52% to 42% for this period. Among 7596 sick children a decrease in detectability of Нр (+)CagA was from 47,4% to 39,1%. Thus, a comparative analysis of detectability of Нр (+)CagA for the reporting period proved a distinct decrease in indexes among adults and children with chronic gastritis.

Serological diagnostic methods for diagnosing the pathology of the upper digestive tract are of great importance for mass medical examinations. They allow diagnosing the disease in the early (asymptomatic) stage.

There is a tendency to reduce the rates of Helicobacter pylori infection among patients with chronic gastritis, which requires further identification, treatment and prevention among the population.

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