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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">ymj</journal-id><journal-title-group><journal-title xml:lang="ru">Якутский медицинский журнал</journal-title><trans-title-group xml:lang="en"><trans-title>Yakut Medical Journal</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1813-1905</issn><issn pub-type="epub">2312-1017</issn><publisher><publisher-name>ЯНЦ КМП</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.25789/YMJ.2018.64.21</article-id><article-id custom-type="elpub" pub-id-type="custom">ymj-1152</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>АКТУАЛЬНАЯ ТЕМА</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ACTUAL TOPIC</subject></subj-group></article-categories><title-group><article-title>Выявляемость Нelicobacter pylori штамма CAGA у взрослых и детей хроническим гастритом по данным РБ №1-НЦМ</article-title><trans-title-group xml:lang="en"><trans-title>The detectability of Helicobacter pylori CAGA strain in adults and children according to the data of RH№1-NCM</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сосина</surname><given-names>С. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Sosina</surname><given-names>S. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Сосина Светлана Степановна – к.м.н. доцент </p></bio><bio xml:lang="en"><p>Sosina Svetlana S., Associate professor NEFU </p><p>Yakutsk </p></bio><email xlink:type="simple">sosinasveta@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Винокурова</surname><given-names>Ж. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Vinokurova</surname><given-names>Zh.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Винокурова Жанна Валерьевна – зав. клинико-диагностич. лаб. </p></bio><bio xml:lang="en"><p>Zhanna Vinokurova, RH №1 – NCM, chief of clinical and diagnostic laboratory </p><p>Yakutsk </p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Яковлева</surname><given-names>Е. П.</given-names></name><name name-style="western" xml:lang="en"><surname>Yakovleva</surname><given-names>E.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Яковлева Екатерина Петровна – зав. клинико-иммунологич. лаб. </p></bio><bio xml:lang="en"><p>Ekaterina Yakovleva, RH№1 – NCM, chief of clinical and immunological laboratory</p><p>Yakutsk </p></bio><email xlink:type="simple">sosinasveta@gmail.com</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Николаева</surname><given-names>И. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Nikolaeva</surname><given-names>I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Николаева Ирина Николаевна – врач иммунолог  </p></bio><bio xml:lang="en"><p>Irina Nikolaeva, RH№1 – NCM, doctor of clinical and immunological laboratory</p><p> Yakutsk </p></bio><email xlink:type="simple">sosinasveta@gmail.com</email><xref ref-type="aff" rid="aff-4"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Слепцов</surname><given-names>А. П.</given-names></name><name name-style="western" xml:lang="en"><surname>Sleptsov</surname><given-names>A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Слепцов Александр Порфирьевич – к.м.н., доцент </p></bio><bio xml:lang="en"><p>Alexander Sleptsov, Associate professor </p><p>Yakutsk </p></bio><email xlink:type="simple">slepcv@gmail.com</email><xref ref-type="aff" rid="aff-5"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>МИ СВФУ им. М.К. Аммосова</institution><country>Россия</country></aff><aff xml:lang="en"><institution>NEFU, Institute of Medicine</institution><country>Russian Federation</country></aff></aff-alternatives><aff xml:lang="ru" id="aff-2"><institution>РБ №1-НЦМ МЗ РС(Я)</institution><country>Russian Federation</country></aff><aff xml:lang="en" id="aff-3"><institution>RH№1 – NCM</institution><country>Russian Federation</country></aff><aff xml:lang="ru" id="aff-4"><institution>РБ 1-НЦМ</institution><country>Russian Federation</country></aff><aff-alternatives id="aff-5"><aff xml:lang="ru"><institution>МИ СВФУ</institution><country>Россия</country></aff><aff xml:lang="en"><institution>NEFU, Institute of Medicine</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2018</year></pub-date><pub-date pub-type="epub"><day>29</day><month>08</month><year>2025</year></pub-date><volume>0</volume><issue>4</issue><fpage>71</fpage><lpage>72</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Сосина С.С., Винокурова Ж.В., Яковлева Е.П., Николаева И.Н., Слепцов А.П., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Сосина С.С., Винокурова Ж.В., Яковлева Е.П., Николаева И.Н., Слепцов А.П.</copyright-holder><copyright-holder xml:lang="en">Sosina S.S., Vinokurova Z., Yakovleva E., Nikolaeva I., Sleptsov A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://ymj.elpub.ru/jour/article/view/1152">https://ymj.elpub.ru/jour/article/view/1152</self-uri><abstract><p>В статье приведены данные исследования сыворотки крови пациентов взрослых и детей с хроническим гастритом на выявляемость Helicobacter pylori за 2012-2017 гг. Исследование проведено на базе клинико-иммунологической лаборатории республиканской больницы №1-Национальный центр медицины методом иммуноферментного анализа на антитела к антигену Cag A Helicobacter pylori. Отмечается отчетливое снижение выявляемости этих показателей среди взрослых и детей хроническим гастритом.</p></abstract><trans-abstract xml:lang="en"><p>The Republic of Sakha (Yakutia) belongs to Arctic territories. Hard social and economic conditions cause broad development of helicobacter infection in the republic. A comparative analysis of detectability of Helicobacter pylori CagA strain among adults and children with chronic gastritis since 2012 to 2016 according to Republic hospital №1 - National center of medicine (RH №1-NCM) revealed a distinct decrease in these indexes among adults and children with chronic gastritis. Thus it demands its further identification and treatment for prevention of stomach diseases of oncological risk group. This article presents research data of detectability of Helicobacter pylori among adults and children for 6 years in RH №1- NCM clinical-immunological laboratory by method of enzyme immunoassay on antibodies to antigen Cag A Helicobacter pylori. The blood serum of patients from the National center of medicine was the material for this research.</p><p>15868 patients were examined, 6993 of them were revealed Helicobacter pylori Cag A that made 44,1%. The detectability for the research period decreased from 49,6% to 40%. 3827 adults out of 8272 patients were revealed Нр (+) Cag A that made 46,3%, and detectability decreased from 52% to 42% for this period. Among 7596 sick children a decrease in detectability of Нр (+)CagA was from 47,4% to 39,1%. Thus, a comparative analysis of detectability of Нр (+)CagA for the reporting period proved a distinct decrease in indexes among adults and children with chronic gastritis.</p><p>Serological diagnostic methods for diagnosing the pathology of the upper digestive tract are of great importance for mass medical examinations. They allow diagnosing the disease in the early (asymptomatic) stage.</p><p>There is a tendency to reduce the rates of Helicobacter pylori infection among patients with chronic gastritis, which requires further identification, treatment and prevention among the population.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>Крайний Север</kwd><kwd>республика Саха (Якутия)</kwd><kwd>Нelicobacter pylori</kwd><kwd>клинико-иммунологическая лаборатория</kwd><kwd>скрининг</kwd><kwd>диагностика</kwd><kwd>иммуноферментный анализ</kwd><kwd>антитела к антигену Cag A Helicobacter pylori</kwd></kwd-group><kwd-group xml:lang="en"><kwd>Far North</kwd><kwd>Republic of Sakha (Yakutia)</kwd><kwd>Helicobacter pylori</kwd><kwd>Cag A antigen</kwd><kwd>clinical and immunological laboratory</kwd><kwd>RB N1-NCM (Yakutsk)</kwd><kwd>screening</kwd><kwd>diagnosis</kwd><kwd>immunoassay</kwd><kwd>antibodies to Cag A Helicobacter pylori antigen</kwd><kwd>treatment</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Лоскутова К.С. 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