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The analysis of associations of Helicobacter pylori babA gene in patients with clinical outcomes of gastroduodenal diseases in Yakutia

https://doi.org/10.25789/YMJ.2019.68.02

Abstract

In this paper we presented the results of the analysis of associations of the Helicobacter pylori babA gene variants with gastroduodenal diseases (erosive and chronic gastritis) of patients in Yakutia. It was shown that babA2 prevailed in patients with erosive gastritis than in patients with chronic gastritis, while babA1 was more common in patients with chronic gastritis, than in patients with erosive gastritis. In addition, it was shown that babA2 was more common in men than in women and it is indicating that the infection of men with the H. pylori strain with a babA2 gene variant may be an additional risk factor for more severe gastroduodenal diseases.

About the Authors

N. N. Gotovtsev
Federal State Budgetary Scientific Institution "Yakut Science Center of Complex Medical Problems"
Russian Federation

Gotovtsev Nyurgun Naumovich – Scientific researcher, Laboratory of Molecular Genetics

677010, Sakha Republic, Yakutsk, Sergelyakhskoye Shosse, 4. Phone: 89141062015



N. A. Barashkov
Federal State Budgetary Scientific Institution "Yakutsk Scientific Center of Complex Medical Problems"
Russian Federation

Barashkov Nikolay Alekseevich – Candidate of biological sciences, Head of laboratory of Molecular genetics

677010, Sakha Republic, Yakutsk, Sergelyakhskoye Shosse, 4. Phone: 8-(4112) 32-19-81



T. V. Borisova
Federal State Autonomous Educational Institution of Higher Education "North-Eastern Federal University. M.K. Ammosov "
Russian Federation

Borisova Tuyara Valerievna – student, Institute of Natural Sciences

677000, Yakutsk, Kulakovsky st. 48. Phone: 89644290223



M. V. Pak
Republican Hospital No. 1 National Center of Medicine
Russian Federation

Pak Maria Vladimirovna – endoscopist of the endoscopic department

677010, Sakha Republic, Yakutsk, Sergelyakhskoye Shosse, 4



M. P. Alexeeva
Republican Hospital No. 1 National Center of Medicine
Russian Federation

Alexeeva Mavra Pavlovna – endoscopist of the endoscopic department

677010, Sakha Republic, Yakutsk, Sergelyakhskoye Shosse, 4



N. N. Innokentyeva
Federal State Autonomous Educational Institution of Higher Education "North-Eastern Federal University M.K. Ammosov "
Russian Federation

Innokentyeva Natalya Nikolaevna – Post-graduate student, Medical Institute

677010, Yakutsk, Oyunsky st. 27. Phone: 8-(4112) 36-30-46



K. S. Loskutova
Republican Hospital No. 1 National Center of Medicine
Russian Federation

Loskutova Kiunniai Savvichna – Candidate of Medical Science, Head of the Pathoanatomical department

677010, Sakha Republic, Yakutsk, Sergelyakhskoye Shosse, 4



V. G. Pshennikova
Federal State Budgetary Scientific Institution "Yakutsk Scientific Center for Complex Medical Problems"
Russian Federation

Pshennikova Vera Gennadievna – Candidate of Biological Sciences, Head of laboratory of Populational Genetics

677010, Sakha Republic, Yakutsk, Sergelyakhskoye Shosse, 4. Phone: 8-(4112) 32-19-81



A. M. Rafailov
Federal State Autonomous Educational Institution of Higher Education "North-Eastern Federal University. M.K. Ammosov "
Russian Federation

Rafailov Adum Mikhailovich – Candidate of Biological Sciences, Associate Professor, Department of Biology, Institute of Natural Sciences

677010, Sakha Republic, Yakutsk, Kulakovsky st. 48. Phone: 8-(4112) 49-68-42



S. N. Lekhanova
Federal State Autonomous Educational Institution of Higher Education "North-Eastern Federal University M.K. Ammosov"
Russian Federation

Lekhanova Sargylana Nikolaevna – Candidate of Medical Science, Associate Professor, Medical Institute

677010, Yakutsk, Oyunsky st. 27. Phone: 8-(4112) 36-30-46



S. A. Fedorova
Federal State Autonomous Educational Institution of Higher Education "North-Eastern Federal University M.K. Ammosov"
Russian Federation

Fedorova Sardana Arkadievna – Doctor of biological sciences, Head of the Research Laboratory of Molecular Biology Institute of Natural Sciences

677010, Sakha Republic, Yakutsk, Kulakovsky st. 46.



M. N. Sidorov
Yakut State Agricultural Academy
Russian Federation

Sidorov Mikhail Nikolaevich – candidate of veterinary sciences, Associate Professor, Department of veterinary and sanitary examination and hygiene

Yakutsk, Kalandarashvili, 21, building 2, sq. 20 Republic of Sakha (Yakutia), 677013



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Review

For citations:


Gotovtsev N.N., Barashkov N.A., Borisova T.V., Pak M.V., Alexeeva M.P., Innokentyeva N.N., Loskutova K.S., Pshennikova V.G., Rafailov A.M., Lekhanova S.N., Fedorova S.A., Sidorov M.N. The analysis of associations of Helicobacter pylori babA gene in patients with clinical outcomes of gastroduodenal diseases in Yakutia. Yakut Medical Journal. 2019;(4):11-14. https://doi.org/10.25789/YMJ.2019.68.02

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ISSN 1813-1905 (Print)
ISSN 2312-1017 (Online)