The analysis of associations of Helicobacter pylori babA gene in patients with clinical outcomes of gastroduodenal diseases in Yakutia
https://doi.org/10.25789/YMJ.2019.68.02
Abstract
In this paper we presented the results of the analysis of associations of the Helicobacter pylori babA gene variants with gastroduodenal diseases (erosive and chronic gastritis) of patients in Yakutia. It was shown that babA2 prevailed in patients with erosive gastritis than in patients with chronic gastritis, while babA1 was more common in patients with chronic gastritis, than in patients with erosive gastritis. In addition, it was shown that babA2 was more common in men than in women and it is indicating that the infection of men with the H. pylori strain with a babA2 gene variant may be an additional risk factor for more severe gastroduodenal diseases.
About the Authors
N. N. GotovtsevRussian Federation
Gotovtsev Nyurgun Naumovich – Scientific researcher, Laboratory of Molecular Genetics
677010, Sakha Republic, Yakutsk, Sergelyakhskoye Shosse, 4. Phone: 89141062015
N. A. Barashkov
Russian Federation
Barashkov Nikolay Alekseevich – Candidate of biological sciences, Head of laboratory of Molecular genetics
677010, Sakha Republic, Yakutsk, Sergelyakhskoye Shosse, 4. Phone: 8-(4112) 32-19-81
T. V. Borisova
Russian Federation
Borisova Tuyara Valerievna – student, Institute of Natural Sciences
677000, Yakutsk, Kulakovsky st. 48. Phone: 89644290223
M. V. Pak
Russian Federation
Pak Maria Vladimirovna – endoscopist of the endoscopic department
677010, Sakha Republic, Yakutsk, Sergelyakhskoye Shosse, 4
M. P. Alexeeva
Russian Federation
Alexeeva Mavra Pavlovna – endoscopist of the endoscopic department
677010, Sakha Republic, Yakutsk, Sergelyakhskoye Shosse, 4
N. N. Innokentyeva
Russian Federation
Innokentyeva Natalya Nikolaevna – Post-graduate student, Medical Institute
677010, Yakutsk, Oyunsky st. 27. Phone: 8-(4112) 36-30-46
K. S. Loskutova
Russian Federation
Loskutova Kiunniai Savvichna – Candidate of Medical Science, Head of the Pathoanatomical department
677010, Sakha Republic, Yakutsk, Sergelyakhskoye Shosse, 4
V. G. Pshennikova
Russian Federation
Pshennikova Vera Gennadievna – Candidate of Biological Sciences, Head of laboratory of Populational Genetics
677010, Sakha Republic, Yakutsk, Sergelyakhskoye Shosse, 4. Phone: 8-(4112) 32-19-81
A. M. Rafailov
Russian Federation
Rafailov Adum Mikhailovich – Candidate of Biological Sciences, Associate Professor, Department of Biology, Institute of Natural Sciences
677010, Sakha Republic, Yakutsk, Kulakovsky st. 48. Phone: 8-(4112) 49-68-42
S. N. Lekhanova
Russian Federation
Lekhanova Sargylana Nikolaevna – Candidate of Medical Science, Associate Professor, Medical Institute
677010, Yakutsk, Oyunsky st. 27. Phone: 8-(4112) 36-30-46
S. A. Fedorova
Russian Federation
Fedorova Sardana Arkadievna – Doctor of biological sciences, Head of the Research Laboratory of Molecular Biology Institute of Natural Sciences
677010, Sakha Republic, Yakutsk, Kulakovsky st. 46.
M. N. Sidorov
Russian Federation
Sidorov Mikhail Nikolaevich – candidate of veterinary sciences, Associate Professor, Department of veterinary and sanitary examination and hygiene
Yakutsk, Kalandarashvili, 21, building 2, sq. 20 Republic of Sakha (Yakutia), 677013
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Review
For citations:
Gotovtsev N.N., Barashkov N.A., Borisova T.V., Pak M.V., Alexeeva M.P., Innokentyeva N.N., Loskutova K.S., Pshennikova V.G., Rafailov A.M., Lekhanova S.N., Fedorova S.A., Sidorov M.N. The analysis of associations of Helicobacter pylori babA gene in patients with clinical outcomes of gastroduodenal diseases in Yakutia. Yakut Medical Journal. 2019;(4):11-14. https://doi.org/10.25789/YMJ.2019.68.02