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Early diagnosis of necrotizing enterocolitis in the newborns

Abstract

At present, necrotizing enterocolitis (NEC) hasn’t objective reliable markers for its early determination. This article presents results of studying of the structural and functional properties of the erythrocyte membranes with original method of automatic registration of the acid and osmotic erythrograms in 50 healthy and 90 newborns with NEC. As a result of our research we received two reliable markers changing their values, depending on the NEC stages.

About the Authors

R. L. Shcherbinin
БУЗ ВО ВОДКБ №1
Russian Federation


V. A. Vecherkin
ФГБОУ ВО «ВГМУ им .Н.Н. Бурденко»
Russian Federation


S. G. Rezvan
ФГБОУ ВО «ВГУ»
Russian Federation


V. A. Ptitsyn
ФГБОУ ВО «ВГМУ им. Н.Н. Бурденко»
Russian Federation


References

1. Gitelzon I.I. The composition of red blood in normal and pathology / I.I. Gitelzon. – Tomsk, I960. – P. 187.

2. Gitelzon, I.A. Terskov // Voprosyi biofiziki, biohimii i patologii eritrotsitov. – Krasnoyarsk, 1960. – P. 85 -99.

3. Karavaeva S.A. Diagnostics and features of the clinical course of necrotizing enterocolitis in children / S.A. Karavaeva // Vestnik hirurgii. – 2002. – V.161. – №4.-P.41-46.

4. Karavaeva S.A. Surgical treatment of necrotic enterocolitis: author’s abstract. dis. Dr. med. Sciences / S.A. Karavaeva. – SPb., 2002. – 291 p.

5. Karavaeva S.A. Tissue hypoxia as the cause of necrotizing enterocolitis in newborns / S.A. Karavaeva, V.G. Bairov, T.K. Nemilova // Materials of the III International Congress of Nordic Countries and Regions. – PetrozavodskParis, 1999. – P. 154.

6. Treatment of ulcerative-necrotic enterocolitis in newborns with low and extreme body weight at birth / O.G. Mokrushina [et al.] //Modern technologies in pediatrics and children’s surgery: materials of the VIII Russian congress. – M., 2009.

7. Necrotizing enterocolitis as a problem of surgical neonotology: a 19-year experience of treatment / S.A. Karavaeva, V.G. Bairov, T.K. Nemilova [et al.]. – The II International Congress of the Nordic Countries and Regions. – Kondopoga, 1998. – P. 74-75.

8. Necrotizing enterocolitis in newborns: new views and trends Yu.A. / Kozlov, V.A. Novozhilov, K.A. Kovalkov [et al.] // Detskaya hirurgiya. – 2016. – №20 (4). – P.188-194.

9. Neonatology. National guide / ed. N.N. Volodin. – M.: GEOTAR-Media, 2008. – 451 p.

10. Rezvan S.G. Analysis of molecular mechanisms of interaction of synthetic homologs of retinol with components of the erythrocyte membrane and free hemoglobin: dis. cand. biol. sciences / S.G. Rezvan. -Voronezh, 1996. – 240 p.

11. The role of laparoscopy in the diagnosis of enterocolitis in newborns / O.G. Mokrushina, A.F. Dronov, A.N. Smirnov [et al.] // Materials of the VI Russian Congress Modern technologies in pediatrics and pediatric surgery, M., 2007. – P.280.

12. Studenikin M.Ya. Hemolitic anemia in children / M.Ya. Studenikin, A.I. Evdokimova. – Tashkent: Medicine, 1979. – 285 p.

13. Shabalov N.P. Neonatology: textbook. 2 vol. / N.P. Shabalov. – 3rd ed., rev. and add. – M.: MEDPress-Inform, 2004. – 608 p.

14. Shumikhin V.S. Modern Technologies in Pediatrics and Pediatric Surgery: // Proceedings of the VIII Russian Congress. – M., 2009. – P.307 – 308.

15. Epidemiology of infections in very low birth weight infants. Polish Neonatology Network research / E.Helwich [et al.] // Med Wieku Rozwoj. – 2013. – Vol. 17. – №3. –P. 224-231.

16. Necrotizing Enterocolitis in Full Term Neonates: Is There Always an Underlying Cause? /O. Abbo, L. Harper, J.-L. Michel [et al.] //Journal of Neonatal Surgery. – 2013. –Vol. 2. – №3.

17. Pandey A. Conservative Management of Pneumoperitoneum in Necrotising Enterocolitis – Is it Possible? /A. Pandey, S.P. Singh, V. Gupta, R. Verma //Journal of Neonatal Surgery. – 2016. – Vol. 5. – №2.

18. Phad N. Intestinal Strictures Post-Necrotising Enterocolitis: Clinical Profile and Risk Factors / N. Phad, A. Trivedi, D. Todd, A. Lakkundi // Journal of Neonatal Surgery. – 2014. – Vol 3. – №4.


Review

For citations:


Shcherbinin R.L., Vecherkin V.A., Rezvan S.G., Ptitsyn V.A. Early diagnosis of necrotizing enterocolitis in the newborns. Yakut Medical Journal. 2017;(4):34-37.

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ISSN 1813-1905 (Print)
ISSN 2312-1017 (Online)